記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1021/acsanm.5c01034

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1039/d5ra08200e

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

While the utility of supported metal and alloy clusters as catalytic materials is widely recognized, their precise synthesis remains a challenge. Here, we demonstrate the precise synthesis of these clusters via metallopeptides. This technique is characterized by its ability to be automated using Merrifield's solid-phase peptide synthesis (SPPS). Metallopeptides with iron and platinum complexes in their side chains have been prepared using this SPPS. These metallopeptides were successfully transformed into the corresponding supported metal clusters by heating in a hydrogen atmosphere.

DOI： 10.1039/d4sc04400b

PubMed

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

Migrasomes are extracellular vesicles that form on the retraction fibers of migrating cells. In this study, we report the formation of migrasome-like vesicles enriched in tetraspanin 4 and containing cytoplasmic components in response to hypoosmotic stress. When migrating cells were subjected to hypoosmotic stress, vesicles with a size distribution of 0.5 to 2 μm formed on the retraction fibers, and vanished in a few minutes. The vesicles are rich in cholesterol, and their number was reduced when cells were pretreated with lipoprotein-deficient serum. The formation of migrasome-like vesicles upon hypoosmotic stress may provide biophysical cues regarding the cellular response to this external stimulus in cells and tissues.

DOI： 10.1002/1873-3468.14816

PubMed

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記述言語：日本語   掲載種別：学位論文（博士）  

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