Updated on 2026/03/12

写真a

 
SAITO SHOGO
 
Organization
School of Materials and Chemical Technology Assistant Professor
Title
Assistant Professor
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Research Interests

  • 生物化学工学

  • ペプチド

Research Areas

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering

  • Life Science / Cell biology

Papers

  • Integration of Peptide Array Screening and Machine Learning for the Discovery of Peptides Directing Triangular Gold Nanoplate Formation

    Saito, S., Oka, R., Ikuta, T., Abe, Y., Choi, Y., Ohashi, T., Critchley, K., Choi, J., Evans, S.D., Tanaka, M., Okochi, M.

    ACS Applied Nano Materials   8 ( 26 )   2025.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsanm.5c01034

    Scopus

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  • Non-erythrocyte spectrin network preferentially stabilizes flat membrane and enhances cell stiffness

    Komikawa, T., Miyake, T., Morooka, M., Kawakami, R., Saito, S., Critchley, K., Evans, S.D., Okochi, M., Tanaka, M.

    Rsc Advances   15 ( 58 )   2025

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d5ra08200e

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  • Synthesis of atom-precise supported metal clusters via solid-phase peptide synthesis. International journal

    Takane Imaoka, Nanami Antoku, Yusuke Narita, Kazuki Nishiyama, Kenji Takada, Shogo Saito, Masayoshi Tanaka, Mina Okochi, Miftakhul Huda, Makoto Tanabe, Wang-Jae Chun, Kimihisa Yamamoto

    Chemical science   15 ( 36 )   14931 - 7   2024.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    While the utility of supported metal and alloy clusters as catalytic materials is widely recognized, their precise synthesis remains a challenge. Here, we demonstrate the precise synthesis of these clusters via metallopeptides. This technique is characterized by its ability to be automated using Merrifield's solid-phase peptide synthesis (SPPS). Metallopeptides with iron and platinum complexes in their side chains have been prepared using this SPPS. These metallopeptides were successfully transformed into the corresponding supported metal clusters by heating in a hydrogen atmosphere.

    DOI: 10.1039/d4sc04400b

    PubMed

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  • Osmotic stress induces the formation of migrasome-like vesicles. International journal

    Koki Yoshikawa, Shogo Saito, Tetsuya Kadonosono, Masayoshi Tanaka, Mina Okochi

    FEBS letters   2024.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    Migrasomes are extracellular vesicles that form on the retraction fibers of migrating cells. In this study, we report the formation of migrasome-like vesicles enriched in tetraspanin 4 and containing cytoplasmic components in response to hypoosmotic stress. When migrating cells were subjected to hypoosmotic stress, vesicles with a size distribution of 0.5 to 2 μm formed on the retraction fibers, and vanished in a few minutes. The vesicles are rich in cholesterol, and their number was reduced when cells were pretreated with lipoprotein-deficient serum. The formation of migrasome-like vesicles upon hypoosmotic stress may provide biophysical cues regarding the cellular response to this external stimulus in cells and tissues.

    DOI: 10.1002/1873-3468.14816

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  • 細胞外小胞ミグラソームを捕捉するペプチド界面の開発と小胞による炎症反応の誘導

    齊藤彰吾

    2023.3

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    Language:Japanese   Publishing type:Doctoral thesis  

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Awards

  • 小澤・吉川記念賞

    2024   公益信託小澤・吉川エレクトロニクス研究助成基金   ペプチド修飾グラフェン電界効果トランジスタを用いたがん細胞由来エクソソームの検出

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Research Projects

  • 細胞遊走により形成される生体膜小胞ミグラソームを介した炎症反応の誘導

    Grant number:24K01266  2024.4 - 2027.3

    日本学術振興会  科学研究費助成事業  基盤研究(B)

    大河内 美奈, 齊藤 彰吾

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    Grant amount:\18590000 ( Direct Cost: \14300000 、 Indirect Cost:\4290000 )

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