The Japanese Biochemical Society

Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells 査読

Fumimasa Kubo, Donna Maretta Ariestanti, Souta Oki, Taku Fukuzawa, Ryotaro Demizu, Tomoya Sato, Rahmaningsih Mara Sabirin, Shigehisa Hirose, Nobuhiro Nakamura

Respiratory Research   20 ( 1 )   2019年12月

Ubiquitin System 招待 査読

Nobuhiro Nakamura

International Journal of Molecular Sciences   19 ( 4 )   1080 - 1080   2018年4月

Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear 査読

Hiroko Matsumoto, Shoko Fujiwara, Hisako Miyagi, Nobuhiro Nakamura, Yasuhiro Shiga, Toshihiro Ohta, Mikio Tsuzuki

MARINE BIOTECHNOLOGY   19 ( 5 )   430 - 440   2017年10月

Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression. 査読

Miyagi, Hisako, Nag, Kakon, Sultana, Naznin, Munakata, Keijiro, Hirose, Shigehisa, Nakamura, Nobuhiro

Gene   577 ( 2 )   265 - 274   2016年

USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase. 査読

Harada, Kumi, Kato, Masako, Nakamura, Nobuhiro

International journal of molecular sciences   17 ( 11 )   2016年

Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation 査読

Ariestanti, Donna Maretta, Ando, Hikaru, Hirose, Shigehisa, Nakamura, Nobuhiro

Journal of Biological Chemistry   290 ( 17 )   11032 - 11040   2015年

Ligand-induced internalization, recycling, and resensitization of adrenomedullin receptors depend not on CLR or RAMP alone but on the receptor complex as a whole 査読

Nag, Kakon, Sultana, Naznin, Kato, Akira, Dranik, Anna, Nakamura, Nobuhiro, Kutsuzawa, Koichi, Hirose, Shigehisa, Akaike, Toshihiro

General and Comparative Endocrinology   212   156 - 162   2015年

Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6 査読

Nakamura, Nobuhiro, Harada, Kumi, Kato, Masako, Hirose, Shigehisa

Experimental Cell Research   328 ( 1 )   207 - 216   2014年

Close association of carbonic anhydrase (CA2a and CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake 査読

Ito, Yusuke, Kobayashi, Sayako, Nakamura, Nobuhiro, Miyagi, Hisako, Esaki, Masahiro, Hoshijima, Kazuyuki, Hirose, Shigehisa

Frontiers in Physiology   4   2013年

Identification and properties of a novel variant of NBC4 (Na+/HCO3- co-transporter 4) that is predominantly expressed in the choroid plexus 査読

Fukuda, Hidekazu, Hirata, Taku, Nakamura, Nobuhiro, Kato, Akira, Kawahara, Katsumasa, Wakabayashi, Shigeo, Chang, Min-Hwang, Romero, Michael F., Hirose, Shigehisa

Biochemical Journal   450   179 - 187   2013年

Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D 査読

Fukuzawa, Taku, Ishida, Junji, Kato, Akira, Ichinose, Taro, Ariestanti, Donna Maretta, Takahashi, Tomoya, Ito, Kunitoshi, Abe, Jumpei, Suzuki, Tomohiro, Wakana, Shigeharu, Fukamizu, Akiyoshi, Nakamura, Nobuhiro, Hirose, Shigehisa

Plos One   8 ( 7 )   2013年

MARCH7 E3 ubiquitin ligase is highly expressed in developing spermatids of rats and its possible involvement in head and tail formation 査読

Zhao, Boqiang, Ito, Kunitoshi, Iyengar, Prasanna Vasudevan, Hirose, Shigehisa, Nakamura, Nobuhiro

Histochemistry and Cell Biology   139 ( 3 )   447 - 460   2013年

Ubiquitination regulates the morphogenesis and function of sperm organelles. 査読

Nakamura, Nobuhiro

Cells   2 ( 4 )   732 - 50   2013年

Identification of SAMT family proteins as substrates of MARCH11 in mouse spermatids 査読

Yogo, Keiichiro, Tojima, Hidehiro, Ohno, Jun-ya, Ogawa, Takuya, Nakamura, Nobuhiro, Hirose, Shigehisa, Takeya, Tatsuo, Kohsaka, Tetsuya

Histochemistry and Cell Biology   137 ( 1 )   53 - 65   2012年

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound beta(2)-adrenergic receptors 査読

Han, Sang-oh, Xiao, Kunhong, Kim, Jihee, Wu, Jiao-Hui, Wisler, James W., Nakamura, Nobuhiro, Freedman, Neil J., Shenoy, Sudha K.

Journal of Cell Biology   199 ( 5 )   817 - 830   2012年

Membrane-associated RING-CH 10 (MARCH10 Protein) Is a Microtubule-associated E3 Ubiquitin Ligase of the Spermatid Flagella 査読

Iyengar, Prasanna Vasudevan, Hirota, Tsuyoshi, Hirose, Shigehisa, Nakamura, Nobuhiro

Journal of Biological Chemistry   286 ( 45 )   39082 - 39090   2011年

The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function. 査読

Nakamura, Nobuhiro

Membranes   1 ( 4 )   354 - 393   2011年

Rhesus Glycoprotein P2 (Rhp2) Is a Novel Member of the Rh Family of Ammonia Transporters Highly Expressed in Shark Kidney 査読

Nakada, Tsutomu, Westhoff, Connie M., Yamaguchi, Yoko, Hyodo, Susumu, Li, Xiaojin, Muro, Takayuki, Kato, Akira, Nakamura, Nobuhiro, Hirose, Shigehisa

Journal of Biological Chemistry   285 ( 4 )   2653 - 2664   2010年

Identification of zebrafish Fxyd11a protein that is highly expressed in ion-transporting epithelium of the gill and skin and its possible role in ion homeostasis 査読

Saito, Kaori, Nakamura, Nobuhiro, Ito, Yusuke, Hoshijima, Kazuyuki, Esaki, Masahiro, Zhao, Boqiang, Hirose, Shigehisa

Frontiers in Physiology   1   2010年

A Novel Potential Role for Gametogenetin-Binding Protein 1 (GGNBP1) in Mitochondrial Morphogenesis During Spermatogenesis in Mice 査読

Aihara, Takeshi, Nakamura, Nobuhiro, Honda, Shinji, Hirose, Shigehisa

Biology of Reproduction   80 ( 4 )   762 - 770   2009年

Mechanism of development of ionocytes rich in vacuolar-type H+-ATPase in the skin of zebrafish larvae 査読

Esaki, Masahiro, Hoshijima, Kazuyuki, Nakamura, Nobuhiro, Munakata, Keijiro, Tanaka, Mikiko, Ookata, Kayoko, Asakawa, Kazuhide, Kawakami, Koichi, Wang, Weiyi, Weinberg, Eric S., Hirose, Shigehisa

Developmental Biology   329 ( 1 )   116 - 129   2009年

Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane 査読

Nakamura, Nobuhiro, Hirose, Shigehisa

Molecular Biology of the Cell   19 ( 5 )   1903 - 1911   2008年

MARCH-XI, a novel transmembrane ubiquitin ligase implicated in ubiquitin-dependent protein sorting in developing spermatids 査読

Morokuma, Yuri, Nakamura, Nobuhiro, Kato, Akira, Notoya, Michitaka, Yamamoto, Yoko, Sakai, Yasuhiro, Fukuda, Hidekazu, Yamashina, Shohei, Hirata, Yukio, Hirose, Shigehisa

Journal of Biological Chemistry   282 ( 34 )   24806 - 24815   2007年

MARCH-V is a novel mitofusin 2-and Drp1-binding protein able to change mitochondrial morphology 査読

Nakamura, Nobuhiro, Kimura, Yasuo, Tokuda, Masaki, Honda, Shinji, Hirose, Shigehisa

Embo Reports   7 ( 10 )   1019 - 1022   2006年

MARCH-III is a novel component of endosomes with properties similar to those of MARCH-II 査読

Fukuda, H, Nakamura, N, Hirose, S

Journal of Biochemistry   139 ( 1 )   137 - 145   2006年

Role of C-terminus of Kir7.1 potassium channel in cell-surface expression 査読

Tateno, T, Nakamura, N, Hirata, Y, Hirose, S

Cell Biology International   30 ( 3 )   270 - 277   2006年

MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking 査読

Nakamura, N, Fukuda, H, Kato, A, Hirose, S

Molecular Biology of the Cell   16 ( 4 )   1696 - 1710   2005年

腎K+分泌能の発達における内向き整流性K+チャネル(ROMK,Kir7.1)の発現

鈴木 喜郎, 安岡 有紀子, 中村 信大, 広瀬 茂久, 河原 克雅

発達腎研究会誌   12 ( 1 )   13 - 15   2004年9月

Expression of the K+ channel Kir7.1 in the developing rat kidney: Role in K+ excretion 査読

Suzuki, Y, Yasuoka, Y, Shimohama, T, Nishikitani, M, Nakamura, N, Hirose, S, Kawahara, K

Kidney International   63 ( 3 )   969 - 975   2003年

RING finger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica 査読

Miyamoto, K, Nakamura, N, Kashiwagi, M, Honda, S, Kato, A, Hasegawa, S, Takei, Y, Hirose, S

European Journal of Biochemistry   269 ( 24 )   6152 - 6161   2002年

Complex structure and regulation of expression of the rat gene for inward rectifier potassium channel Kir7.1 査読

Nakamura, N, Suzuki, Y, Ikeda, Y, Notoya, M, Hirose, S

Journal of Biological Chemistry   275 ( 36 )   28276 - 28284   2000年

Localization of inward rectifier potassium channel Kir7.1 in the basolateral membrane of distal nephron and collecting duct 査読

Ookata, K, Tojo, A, Suzuki, Y, Nakamura, N, Kimura, K, Wilcox, CS, Hirose, S

Journal of the American Society of Nephrology   11 ( 11 )   1987 - 1994   2000年

Inward rectifier potassium channel Kir7.1 is highly expressed in the ion-transporting epithelial cells: implication for a functional coupling with Na+,K+-ATPase

Nakamura, N., Suzuki, Y., Sakuta, H., Ookata, K., Kawahara, K., Hirose, S., Suketa, Y., Carafoli, E., Lazdunski, M., Mikoshiba, K., Okada, Y., Wright, EM

Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels   1208   2000年

Na,K-ATPaseとの機能共役が期待されるKチャネル(Kir7.1)の細胞局在とTSH応答

中村 信大, 鈴木 喜郎, 池田 雄吾, 大方 香代子, 河原 克雅, 広瀬 茂久

生化学   71 ( 8 )   807 - 807   1999年8月

新しいカリウムチャネルKir7.1の遠位側ネフロンの基底膜における局在

大方 香代子, 藤乗 嗣泰, 中村 信大, 鈴木 喜郎, 木村 健二郎, 後藤 淳郎, 藤田 敏郎, 広瀬 茂久

日本腎臓学会誌   41 ( 3 )   275 - 275   1999年5月

Inwardly rectifying K+ channel Kir7.1 is highly expressed in thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase 査読

Nakamura, N., Suzuki, Y., Sakuta, H., Ookata, K., Kawahara, K., Hirose, S.

Biochemical Journal   342 ( 2 )   329 - 336   1999年

Identification by differential display of a hypertonicity-inducible inward rectifier potassium channel highly expressed in chloride cells 査読

Suzuki, Y, Itakura, M, Kashiwagi, M, Nakamura, N, Matsuki, T, Sakuta, H, Naito, N, Takano, K, Fujita, T, Hirose, S

Journal of Biological Chemistry   274 ( 16 )   11376 - 11382   1999年

Molecular characterization and immunohistochemical localization of a bicarbonate transporter highly and predominantly expressed in rat choroid plexus epithelial cells

Fukuda, H, Hirata, T, Nakamura, N, Wakabayashi, S, Romero, MF, Hirose, S

Faseb Journal   19 ( 5 )   A1645 - A1645   2005年

Identification of a novel syntaxin-6-binding protein

Nakamura, Nobuhiro, Fukuda, Hidekazu, Kato, Akira, Hirose, Shigehisa

Cell Structure and Function   30   20 - 20   2005年

Kdg2, a novel multidomain protein involved in the regulation of recycling endosomal trafficking.

Fukuda, H., Nakamura, N., Kato, A., Hirose, S.

Molecular & Cellular Proteomics   2 ( 9 )   753 - 753   2003年

Kdg1, a novel RING-finger membrane protein that localizes in the recycling endosome compartment

Nakamura, N, Fukuda, H, Ikeda, Y, Hirose, S

Molecular Biology of the Cell   13   397A - 398A   2002年

Inwardly rectifying potassium channel Kir7.1 is highly expressed in the thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase

N Nakamura, Y Suzuki, H Sakuta, K Ookata, K Kawahara, S Hirose

Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels   Vol. ( No. )   39 - 40   2000年

Cloning and properties of a hypertonicity-inducible inward rectifier K+ channel from euryhaline eels

Suzuki, Y, Nakamura, N, Sakuta, H, Takano, K, Fujita, T, Hirose, S, Okada, Y

Cell Volume Regulation   1160   159 - 166   1998年

E3ユビキチンリガーゼMARCH2によるSyntaxin-6のユビキチン化の解析

菊地 英一, 加藤 真子, 安濃 卓人, 中村 信大

第93回日本生化学会大会  2020年9月 

Increased expression of polyamine biosynthetic and catabolic enzymes in alveolar macrophages of Ig-Hepta knockout mice

Hikaru ANDO, Donna Maretta Ariestanti, Shigehisa HIROSE, Nobuhiro NAKAMURA

The 9th TOIN International Symposium on Biomedical Engineering 2014  2014年11月 

Early cardiac connexin acts as a Ca2+ hemichannel that regulates heart morphogenesis via NFATc4 activation

Naznin Sultana, Kakon Nag, Akira Kato, Atsushi Kawakami, Koichi Kutsuzawa, Toshihiro Akaike, Shigehisa Hirose, Nobuhiro Nakamura

The ISSCR 12th Annual Meeting  2014年6月 

Regulation of mitochondrial morphology by ubiquitination

Nobuhiro Nakamura

International Marine Biotechnology Symposium  2013年5月 

USP19 deubiquitinating enzyme regulates stability of TEB4 ubiquitin ligase

Nobuhiro NAKAMURA, Yuki EBISAWA, Shigehisa HIROSE

Joint Meeting of JSDB 45th and JSCB 64th  2012年5月 

Regulation of mitochondrial morphology by ubiquitination 招待

Nobuhiro Nakamura

5th Conference of Korean Society for Mitochondrial Research and Medicine  2011年6月 

ミトコンドリア形態制御因子に相互作用する新規ユビキチン化酵素 MARCH-V の同定 招待

中村信大

第30回日本分子生物学会年会・第80回日本生化学会大会合同大会  2007年12月 

Cloning and properties of a hypertonicity-inducible inward rectifier K+ channel from euryhaline eels

Proceedings of the 23rd Taniguchi Foundation Biophysics Symposium  1998年 

Kdg1, a novel RING-finger membrane protein that localizes in the recycling endosome compartment.

42nd american society for cell biology annual meeting  2002年 

Kdg1, a novel RING-finger membrane protein that localizes in the recycling endosome compartment.

42nd american society for cell biology annual meeting  2002年 

Intracellular signaling Mechanism of G-protein coupled receptor ADGRF5

Tomoya Sato, Masako Kato, Humimasa Kubo, Nobuhiro Nakamura

13th Toin International Symposium on Biomedical Engineering  2018年10月 

ヒトGタンパク質共役型受容体ADGRF5のタンパク質発現調節機構の解析

永沢 佑陽, 加藤 真子, 中村 信大

第93回日本生化学会大会  2020年9月 

Gタンパク質共役型受容体Adgrf5の欠損による腎糸球体濾過障壁の構造異常

別府 義彬, 長瀬 美樹, 安東 輝, 栗原 秀剛, 久保 文雅, 沖 颯太, 坂井 健雄, 広瀬 茂久, 中村 信大

第93回日本生化学会大会  2020年9月 

A549細胞におけるUSP30-AS1の発現制御とUSP30の発現への影響の解析

松本 聖慈, 加藤 真子, 中村 信大

第９４回日本生化学大会  2021年11月 

The expression of zebrafish cx36.7 gene is regulated by GATA4 in early heart development

Hisako Miyagi, Ippei Kasajima, Yumiko Tanaka, Keijiro Munakata, Kakon Nag, Naznin Sultana, Shigehisa Hirose, Nobuhiro Nakamura

第47回発生生物学会  2014年5月 

Emphysema-like symptoms in lungs of Ig-Hepta/GPR116-deficient mice

Donna Maretta Ariestanti, Akira Kato, Tomoya Takahashi, Shigehisa Hirose, Nobuhiro Nakamura

7th international adhesion GPCR workshop  2014年6月 

Emphysema-like symptom in Ig-Hepta/Gpr116 knockout mice associated to alveolar macrophage activation

Donna Maretta Ariestanti, Hikaru Ando, Shigehisa Hirose, Nobuhiro Nobuhiro Nakamura

10th Toin International Symposium on Biomedical Engineering  2015年11月 

Regulation of cardiac-specific expression of the zebrafish cx36.7 gene

Hisako Miyagi, Kakon Nag, Naznin Sultana, Keijiro Munakata, Shigehisa Hirose, Nobuhiro Nakamura

Toin International Symposium on Biomedical Engineering  2015年11月 

A novel mechanism for the regulation of the expression of the mitochondrial deubiquitinating enzyme USP30

Mizuho Muto, Masako Kato, Nobuhiro Nakamura

11th Toin International Symposium on Biomedical Engineering  2016年10月 

Adgrf5 deficient mice exhibit bronchial asthma- and fibrosis-like phenotypes

Fumimasa Kubo, Donna Maretta Ariestanti, Souta Oki, Rahmaningsih Mara Sabirin, Ryotarou Demizu, Nobuhiro Nakamura

12th Toin International Symposium on Biomedical Engineering  2017年11月 

Adgrf5欠損マウスは気管支喘息および肺線維症様の表現型を現す

久保 文雅, Donna Ariestanti, 沖 颯太, Rahmaningsih Sabirin, 出水 遼太郎, 中村 信大

2017年度生命科学系学会合同年次大会  2017年12月 

Gタンパク質共役型受容体ADGRF5の欠損は肺血管内皮細胞における炎症性分子の発現と喘息に似た表現型を誘導する

久保 文雅, Donna Ariestanti, 沖 颯太, 福澤拓, 出水 遼太郎, 佐藤朋哉, Rahmaningsih Sabirin, 広瀬茂久, 中村 信大

第91回日本生化学会大会  2018年9月 

Kdg2, a novel multidomain protein involved in the regulation of recycling endosomal trafficking.

HUPO 2nd & IUBMB XIX World Congress  2003年 

Kdg2, a novel multidomain protein involved in the regulation of recycling endosomal trafficking.

HUPO 2nd & IUBMB XIX World Congress  2003年 

Cardiac expression of zebrafish connexin 36.7 is regulated by GATA4 transcription factor

Hisako Miyagi, Ippei Kasajima, Yumiko Tanaka, Keijiro Munakata, Kakon Nag, Naznin Sultana, Shigehisa Hirose, Nobuhiro Nakamura

8th International Symposium on Biomedical Engineering  2013年10月 

The deubiquitinating enzyme USP19 regulates the ERAD pathway by stabilizing the E3 ubiquitin ligases

Kumi Harada, Shigehisa Hirose, Nobuhiro Nakamura

8th International Symposium on Biomedical Engineering  2013年10月 

Regulation of the activity of USP19 deubiquitinating enzyme.

Yuki Ebisawa, Nobuhiro Nakamura

8th International Symposium on Biomedical Engineering  2013年10月 

Control of mitochondrial morphology by ubiquitination and deubiquitination 招待

Nobuhiro NAKAMURA

8th International Symposium on Biomedical Engineering  2013年10月 

Cloning and properties of a hypertonicity-inducible inward rectifier K+ channel from euryhaline eels

Proceedings of the 23rd Taniguchi Foundation Biophysics Symposium  1998年 

ゼブラフィッシュの心筋細胞分化の鍵を担う新規コネキシン分子の機能解析

2013年4月 - 2014年3月

武田科学振興財団  武田科学振興財団ライフサイエンス研究奨励 

中村信大

タンパク質分解にはたらくオルガネラ特異的なユビキチン化制御分子の機能解析

研究課題/領域番号：24570209  2012年4月 - 2015年3月

日本学術振興会  科学研究費助成事業  基盤研究(C)

中村 信大

細胞内Ｃａシグナルのスイッチとなる新発見のコネキシンの生理機能と発現制御機構

研究課題/領域番号：12F02392  2012年4月 - 2015年3月

日本学術振興会  科学研究費助成事業  特別研究員奨励費

中村 信大, SULTANA Naznin, SULTANA N.

コネキシンを介したカルシウムシグナリングによる筋原繊維形成の分子機構の解析

2012年4月 - 2013年3月

倉田記念日立科学技術財団  倉田奨励金 

中村 信大

新型の小胞体脱ユビキチン化酵素の細胞機能と制御機構

研究課題/領域番号：22770123  2010年 - 2011年

日本学術振興会  科学研究費助成事業  若手研究(B)

中村 信大

ミトコンドリア形態制御に関与する新しい分子の分子細胞生物学的な解析

研究課題/領域番号：20770156  2008年 - 2009年

日本学術振興会  科学研究費助成事業  若手研究(B)

中村 信大

細胞内輸送システムに関与する新しい分子の細胞生物学的研究

2004年 - 2005年

Cell biological study for novel molecules involved in intracellular trafficking

2004年 - 2005年