The University of Tokyo   The Faculty of Engineering

- 1989

Shinshu University

1998 - 2001

ルーベン大学（ベルギー） 博士研究員

1997 - 1998

University of Leuven Postdoctral Fellow

1997 - 1998

University of Tokyo Assistant Researcher

1994 - 1997

The University of Tokyo

1994 - 1997

internathional society ofinterferon and cytokine research

internathional society ofinterferon and cytokine research

日本インターフェロン・サイトカイン学会   学会賞選考委員  

日本インターフェロン・サイトカイン学会   ニュースレター委員  

肝細胞研究会   世話人  

Study of time-dependent pharmacokinetics of mouse embryonic stem cell-derived cardiomyocytes for drug screening Reviewed

Yoh-ichi Tagawa

Translational and Regulatory Sciences   2 ( 1 )   7 - 13   2020

MazF activation causes ACA sequence-independent and selective alterations in RNA levels in Escherichia coli Reviewed International journal

Akiyama, Kentaro, Fujisawa, Kazuki, Kondo, Hiro, Netsu, Yuya, Nishikawa, Koji, Takata, Yoshio, Nakamura, Yuya, Kino, Yuta, Ayukawa, Shotaro, Yamamura, Masayuki, Hayashi, Nobuhiro, Tagawa, Yoh-ichi, Nakashima, Nobutaka

Archives of Microbiology   202 ( 1 )   105 - 114   2020

Acetaminophen-induced hepatotoxicity of cultured hepatocytes depends on timing of isolation from light-cycle controlled mice Reviewed International journal

Moriya, Koji, Tamai, Miho, Koga, Takumi, Tanaka, Toshiaki, Tagawa, Yoh-ichi

Genes to Cells   25 ( 4 )   257 - 269   2020

A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-alpha2b. Reviewed

Imada, Takashi, Moriya, Koji, Uchiyama, Masahiko, Inukai, Naoto, Hitotsuyanagi, Mitsuhiro, Masuda, Akiko, Suzuki, Takehiro, Ayukawa, Shotaro, Tagawa, Yo-Ichi, Dohmae, Naoshi, Kohara, Michinori, Yamamura, Masayuki, Kiga, Daisuke

ACS synthetic biology   2018

Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation. Reviewed International journal

Okumura, Hiroki, Nakanishi, Anna, Toyama, Satoshi, Yamanoue, Mai, Yamada, Kana, Ukai, Akane, Hashita, Tadahiro, Iwao, Takahiro, Miyamoto, Tomomi, Tagawa, Yoh-Ichi, Hirabayashi, Masumi, Miyoshi, Ichiro, Matsunaga, Tamihide

Xenotransplantation   26 ( 1 )   e12468   2018

Inhibitory effect of the extract of rhizome of Curcuma longa L in gelatinase activity and its effect on human skin. Reviewed

Muta, Keiko, Inomata, Shinji, Fukuhara, Tadao, Nomura, Junko, Nishiyama, Toshio, Tagawa, Yoh-Ichi, Amano, Satoshi

Journal of bioscience and bioengineering   125 ( 3 )   2018

Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation Reviewed

Masahiko Ito, Suofeng Sun, Takasuke Fukuhara, Ryosuke Suzuki, Miho Tamai, Toyohiko Yamauchi, Kenji Nakashima, Yoh-Ichi Tagawa, Shigetoshi Okazaki, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki

ONCOTARGET   8 ( 33 )   53899 - 53915   2017.8

Metabolomics of an in vitro liver model containing primary hepatocytes assembling around an endothelial cell network: comparative study on the metabolic stability and the effect of acetaminophen treatment

Toyoda Yu, Kashikura Kasumi, Soga Tomoyoshi, Tagawa Yoh-ichi

The Journal of Toxicological Sciences   42 ( 4 )   445 - 454   2017

A novel aldosterone synthase inhibitor ameliorates mortality in pressure-overload mice with heart failure Reviewed

Furuzono, Shinji, Meguro, Masaki, Miyauchi, Satoru, Inoue, Shinichi, Homma, Tsuyoshi, Yamada, Keisuke, Tagawa, Yoh-ichi, Nara, Futoshi, Nagayama, Takahiro

European Journal of Pharmacology   795   58 - 65   2017

Nitric oxide is critical for avoiding hepatic lipid overloading via IL6 induction during liver regeneration after partial hepatectomy in mice. Reviewed

Yu, Yue, Tamai, Miho, Tagawa, Yoh-Ichi

Experimental animals   66 ( 4 )   293 - 302   2017

Optimized Ultrasonic Irradiation Finds Out Ultrastable A beta(1-40) Oligomers Reviewed

Nakajima, Kichitaro, So, Masatomo, Takahashi, Kazuma, Tagawa, Yoh-ichi, Hirao, Masahiko, Goto, Yuji, Ogi, Hirotsugu

Journal of Physical Chemistry B   121 ( 12 )   2603 - 2613   2017

Transdifferentiation of mouse visceral yolk sac cells into parietal yolk sac cells in vitro Reviewed

Yagi, Shinomi, Tagawa, Yoh-ichi, Shiojiri, Nobuyoshi

Biochemical and Biophysical Research Communications   470 ( 4 )   917 - 923   2016

Innate immunity in an in vitro murine blastocyst model using embryonic and trophoblast stem cells Reviewed

Aikawa, Hiroaki, Tamai, Miho, Mitamura, Keisuke, Itmainati, Fakhria, Barber, Glen N., Tagawa, Yoh-ichi

Journal of Bioscience and Bioengineering   117 ( 3 )   358 - 365   2014

An in vitro liver model consisting of endothelial vascular networks surrounded by human hepatoma cell lines allows for improved hepatitis B virus replication Reviewed

Ahn, Sungho, Tamai, Miho, Nakashima, Kenji, Ito, Masahiko, Suzuki, Tetsuro, Tagawa, Yoh-ichi

Journal of Bioscience and Bioengineering   118 ( 1 )   107 - 111   2014

Dynamic chemotactic response of fibroblasts to local stimulation using EGF-immobilized microbeads Reviewed

Aratsu, Fumihiro, Harada, Ichiro, Yoshimura, Soichiro, Cho, Chong-Su, Akaike, Toshihiro, Tagawa, Yoh-ichi

Biomaterials   35 ( 8 )   2471 - 2476   2014

Hybrid sponge comprised of galactosylated chitosan and hyaluronic acid mediates the co-culture of hepatocytes and endothelial cells Reviewed

Shang, Yi, Tamai, Miho, Ishii, Ryusei, Nagaoka, Noriyuki, Yoshida, Yasuhiro, Ogasawara, Masamichi, Yang, Jun, Tagawa, Yoh-ichi

Journal of Bioscience and Bioengineering   117 ( 1 )   99 - 106   2014

Characterization of a Liver Organoid Tissue Composed of Hepatocytes and Fibroblasts in Dense Collagen Fibrils Reviewed

Tamai, Miho, Adachi, Eijiro, Tagawa, Yoh-ichi

Tissue Engineering Part a   19 ( 21-22 )   2527 - 2535   2013

Chimeric analysis of EGFP and DsRed2 transgenic mice demonstrates polyclonal maintenance of pancreatic acini Reviewed

Ryu, Je-Young, Siswanto, Antoni, Harimoto, Kenichi, Tagawa, Yoh-ichi

Transgenic Research   22 ( 3 )   549 - 556   2013

Expression of the rodent-specific alternative splice variant of tryptophanyl-tRNA synthetase in murine tissues and cells Reviewed

Miyanokoshi, Miki, Tanaka, Tomoaki, Tamai, Miho, Tagawa, Yoh-ichi, Wakasugi, Keisuke

Scientific Reports   3   3477   2013

In vitro recapitulation of the urea cycle using murine embryonic stem cell-derived in vitro liver model Reviewed

Tamai, Miho, Aoki, Mami, Nishimura, Akihito, Morishita, Koji, Tagawa, Yoh-ichi

Amino Acids   45 ( 6 )   1343 - 1351   2013

Characterization and neural differentiation of mouse embryonic and induced pluripotent stem cells on cadherin-based substrata Reviewed

Haque, Amranul, Yue, Xiao-Shan, Motazedian, Ali, Tagawa, Yoh-ichi, Akaike, Toshihiro

Biomaterials   33 ( 20 )   5094 - 5106   2012

Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis

Harimoto, Kenichi, Yoshida, Yasuhiro, Yoshihara, Kumiko, Nagaoka, Noriyuki, Matsumoto, Takuya, Tagawa, Yoh-ichi

Dental Materials Journal   31 ( 4 )   674-680 (J-STAGE) - 680   2012

Acetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell Network Reviewed International journal

Toyoda, Yu, Tamai, Miho, Kashikura, Kasumi, Kobayashi, Shunsuke, Fujiyama, Yoichi, Soga, Tomoyoshi, Tagawa, Yoh-ichi

Drug Metabolism and Disposition   40 ( 1 )   169 - 77   2012

Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy

Hayashi, Takuma, Horiuchi, Akiko, Sano, Kenji, Hiraoka, Nobuyoshi, Kasai, Mari, Ichimura, Tomoyuki, Sudo, Tamotsu, Tagawa, Yoh-ichi, Nishimura, Ryuichiro, Ishiko, Osamu, Kanai, Yae, Yaegashi, Nobuo, Aburatani, Hiroyuki, Shiozawa, Tanri, Konishi, Ikuo

Scientific Reports   1   180 - 180   2011

Mitochondrial development of the in vitro hepatic organogenesis model with simultaneous cardiac mesoderm differentiation from murine induced pluripotent stem cells Reviewed

Tamai, Miho, Yamashita, Arisa, Tagawa, Yoh-ichi

Journal of Bioscience and Bioengineering   112 ( 5 )   495 - 500   2011

Expression of human factors CD81, claudin-1, scavenger receptor, and occludin in mouse hepatocytes does not confer susceptibility to HCV entry

Hikosaka, Keisuke, Noritake, Hidenao, Kimura, Wataru, Sultana, Nishat, Sharkar, Mohammad T. K., Tagawa, Yoh-ichi, Uezato, Tadayoshi, Kobayashi, Yoshimasa, Wakita, Takaji, Miura, Naoyuki

Biomedical Research-Tokyo   32 ( 2 )   143 - 150   2011

Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor

Denda, Kimitoshi, Nakao-Wakabayashi, Kanako, Okamoto, Naoki, Kitamura, Naomi, Ryu, Je-Young, Tagawa, Yoh-ichi, Ichisaka, Tomoko, Yamanaka, Shinya, Komada, Masayuki

Journal of Biological Chemistry   286 ( 33 )   2011

Polymeric Membranes for Chiral Separation of Pharmaceuticals and Chemicals

Higuchi, Akon, Tamai, Miho, Ko, Yi-An, Tagawa, Yoh-Ichi, Wu, Yuan-Hsuan, Freeman, Benny D., Bing, Jun-Tang, Chang, Yung, Ling, Qing-Dong

Polymer Reviews   50 ( 2 )   2010

Surface modification of polymeric membranes for low protein binding Reviewed

Higuchi, Akon, Tamai, Miho, Tagawa, Yoh-ichi, Chang, Yung, Ling, Qing-Dong

Membrane Water Treatment   1 ( 2 )   103 - 120   2010

Direct ex vivo expansion of hematopoietic stem cells from umbilical cord blood on membranes Reviewed

Higuchi, Akon, Yang, Siou-Ting, Li, Pei-Tsz, Tamai, Miho, Tagawa, Yoh-ichi, Chang, Yung, Chang, Yu, Ling, Qing-Dong, Hsu, Shih-Tien

Journal of Membrane Science   351 ( 1-2 )   104 - 111   2010

Carbonate apatite-facilitated intracellularly delivered siRNA for efficient knockdown of functional genes Reviewed

Hossain, Sharif, Stanislaus, Anthony, Chua, Ming Jang, Tada, Seiichi, Tagawa, Yoh-ichi, Chowdhury, Ezharul Hogue, Akaike, Toshihiro

Journal of Controlled Release   147 ( 1 )   101 - 108   2010

Adrenomedullin in sinusoidal endothelial cells play protective roles against cold injury of liver International journal

Iinuma, Nobuyoshi, Iinuma, Nobuyoshi, Sakurai, Takayuki, Sakurai, Takayuki, Kamiyoshi, Akiko, Kamiyoshi, Akiko, Ichikawa-Shindo, Yuka, Ichikawa-Shindo, Yuka, Arai, Takuma, Arai, Takuma, Yoshizawa, Takahiro, Yoshizawa, Takahiro, Koyama, Teruhide, Koyama, Teruhide, Uetake, Ryuichi, Uetake, Ryuichi, Kawate, Hisaka, Kawate, Hisaka, Muto, Shin-ichi, Muto, Shin-ichi, Tagawa, Yoh-ichi, Tagawa, Yoh-ichi, Miyagawa, Shinichi, Miyagawa, Shinichi, Shindo, Takayuki, Shindo, Takayuki

Peptides   31 ( 5 )   865 - 71   2010

Characterization of a Variant Virus from Ascitic Fluid of Subacute Granulomatous Serositis in Interferon-gamma-Deficient C57BL/6 Mice Persistently Infected with Murine Coronavirus Strain JHM International journal

Kyuwa, Shigeru, Takagaki, Satoshi, Matsuyama, Shutoku, Taguchi, Fumihiro, Saegusa, Junzo, Iwakura, Yoichiroh, Tagawa, Yoh-Ichi, Yoshikawa, Yasuhiro

Viral Immunology   23 ( 4 )   437 - 42   2010

Isolation and characterization of portal branch ligation-stimulated Hmga2-positive bipotent hepatic progenitor cells International journal

Sakai, Hiroshi, Tagawa, Yoh-ichi, Tamai, Miho, Motoyama, Hiroaki, Ogawa, Shinichiro, Soeda, Junpei, Nakata, Takenari, Miyagawa, Shinichi

Biochemical and Biophysical Research Communications   403 ( 3-4 )   298 - 304   2010

IFN-gamma deficiency worsen Pneumocystis pneumonia with Th17 development in nude mice International journal

Hu, Tao, Takamoto, Masaya, Hida, Sigeaki, Tagawa, Yoh-ichi, Sugane, Kazuo

Immunology Letters   127 ( 1 )   55 - 9   2009

In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors

Motoyama, Hiroaki, Ogawa, Shinichiro, Kubo, Atsushi, Miwa, Shiro, Nakayama, Jun, Tagawa, Yoh-ichi, Miyagawa, Shinichi

Biochemical and Biophysical Research Communications   385 ( 1 )   2009

Hepatoprotective effect of vitamin B-12 on dimethylnitrosamine-induced liver injury

Isoda, Katsuhiro, Kagaya, Noritaka, Akamatsu, Soichiro, Hayashi, Shinji, Tamesada, Makoto, Watanabe, Aiko, Kobayashi, Masakazu, Tagawa, Yoh-ichi, Kondoh, Masuo, Kawase, Masaya, Yagi, Kiyohito

Biological & Pharmaceutical Bulletin   31 ( 2 )   309 - 311   2008

Deficiency of tumour necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury International journal

Murayama, Hideki, Takahashi, Masafumi, Takamoto, Masaya, Shiba, Yuji, Ise, Hirohiko, Koyama, Jun, Tagawa, Yoh-ichi, Iwakura, Yoichiro, Ikeda, Uichi

Cardiovascular Research   80 ( 2 )   175 - 80   2008

Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling Reviewed

Hoshiba, Takashi, Nagahara, Hikaru, Cho, Chong-Su, Tagawa, Yoh-ichi, Akaike, Toshihiro

Biomaterials   28 ( 6 )   1093 - 1104   2007

The role of gamma interferon in acquired host resistance against Staphylococcus aureus infection in mice

Sasaki, S, Tagawa, YI, Iwakura, Y, Nakane, A

Fems Immunology and Medical Microbiology   46 ( 3 )   2006

Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system

Tsutsui, M, Ogawa, S, Inada, Y, Tomioka, E, Kamiyoshi, A, Tanaka, S, Kishida, T, Nishiyama, M, Murakami, M, Kuroda, J, Hashikura, Y, Miyagawa, S, Satoh, F, Shibata, N, Tagawa, YI

Drug Metabolism and Disposition   34 ( 4 )   2006

Collagen synthesis is required for ascorbic acid-enhanced differentiation of mouse embryonic stem cells into cardiomyocytes

Sato, H, Takahashi, M, Ise, H, Yamada, A, Hirose, S, Tagawa, Y, Morimoto, H, Izawa, A, Ikeda, U

Biochemical and Biophysical Research Communications   342 ( 1 )   2006

Effect of surface pre-treatment on durability of resin-based cements bonded to titanium

Tsuchimoto, Y, Yoshida, Y, Takeuchi, M, Mine, A, Yatani, H, Tagawa, Y, Van Meerbeek, B, Suzuki, K, Kuboki, T

Dental Materials   22 ( 6 )   2006

Endogenous alpha CGRP protects against concanavalin A-induced hepatitis in mice

Kainiyoshi, A, Sakurai, T, Ichikawa-Shindo, Y, Fukuchi, J, Kawate, H, Muto, S, Tagawa, Y, Shindo, T

Biochemical and Biophysical Research Communications   343 ( 1 )   2006

The ICOS-ligand K-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system

Qian, XS, Agematsu, K, Freeman, GJ, Tagawa, Y, Sugane, K, Hayashi, T

European Journal of Immunology   36 ( 4 )   2006

Liver Organogenesis from Murine Embryonic Stem Cells(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)

Tagawa Yoh-ichi, Ogawa Shinichiro, Tsutsui Masaru, Kamiyoshi Akiko, Tomioka Eisuke, Kobayashi Shunsuke, Miki Kenji, Isi Ryusei, Nakayama Jun, Hashikura Yasuhiko, Sato Fumiyasu, Nishiyama Masahiko, Akaike Toshihiro, Miyagawa Shinichi

Journal of hard tissue biology   14 ( 2 )   263 - 264   2005.10

Tea catechin epigallocatechin-3-gallate, inhibits rubratoxin B-induced apoptosis of hepatocytes through MAPK p38 pathway

KAGAYA Noritaka, KAMIYOSHI Akiko, TAGAWA Yoh-ichi, NAGASHIMA Hitoshi, KAWASE Masaya, YAGI Kiyohito

JSM Mycotoxins   55 ( 1 )   17 - 22   2005.1

Interaction of rubratoxin B with serum albumin

KAGAYA Noritaka, KAMIYOSHI Akiko, TAGAWA Yoh-ichi, NAGASHIMA Hitoshi, KAWASE Masaya, YAGI Kiyohito

JSM Mycotoxins   55 ( 1 )   23 - 26   2005.1

Suppression of cell death in primary rat hepatocytes by alpha(1)-acid glycoprotein

Kagaya, N, Kamiyoshi, A, Tagawa, YI, Akamatsu, S, Isoda, K, Kawase, M, Yagi, K

Journal of Bioscience and Bioengineering   99 ( 1 )   81 - 83   2005

Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system

Ogawa, S, Tagawa, Y, Kamiyoshi, A, Suzuki, A, Nakayama, J, Hashikura, Y, Miyagawa, S

Stem Cells   23 ( 7 )   2005

Expression of Fas ligand by hepatic macrophages in patients with fulminant hepatic failure

Mita, A, Hashikura, Y, Tagawa, Y, Nakayama, J, Kawakubo, M, Miyagawa, S

American Journal of Gastroenterology   100 ( 11 )   2005

IFN-gamma and TNF-alpha are involved in urushiol-induced contact hypersensitivity in mice

Wakabayashi, T, Hu, DL, Tagawa, YI, Sekikawa, K, Iwakura, Y, Hanada, K, Nakane, A

Immunology and Cell Biology   83 ( 1 )   18 - 24   2005

Tumor necrosis factor-alpha is required for gastritis induced by Helicobacter felis infection in mice International journal

Hasegawa, S, Nishikawa, S, Miura, T, Saito, Y, Madarame, H, Sekikawa, K, Tagawa, Y, Iwakura, Y, Nakane, A

Microbial Pathogenesis   37 ( 3 )   119 - 24   2004

Comparative study on adhesive performance of functional monomers

Yoshida, Y, Nagakane, K, Fukuda, R, Nakayama, Y, Okazaki, M, Shintani, H, Inoue, S, Tagawa, Y, Suzuki, K, De Munck, J, Van Meerbeek, B

Journal of Dental Research   83 ( 6 )   2004

Liver protection by bis(maltolato)zinc(II) complex

Kawase, M, Kagaya, N, Akamatsu, S, Kamiyoshi, A, Muto, S, Tagawa, Y, Yagi, K

Experimental Animals   53 ( 1 )   1 - 9   2004

Transforming growth factor-beta regulates susceptibility of epithelial apoptosis in murine model of colitis International journal

Sakuraba, H, Ishiguro, Y, Yamagata, K, Tagawa, YI, Iwakura, Y, Sekikawa, K, Munakata, A, Nakane, A

Annals of the New York Academy of Sciences   1029   382 - 4   2004

Novel function of rare catechin, epigallocatechin-3-(3 ''-O-methyl)gallate, against cold injury in primary rat hepatocytes

Kagaya, N, Hara, Y, Saijo, R, Kamiyoshi, A, Tagawa, YI, Kawase, M, Yagi, K

Journal of Bioscience and Bioengineering   96 ( 6 )   559 - 563   2003

マウスコロナウイルス感染に対するIFN-γ欠損マウスの感受性のマウス系統差

久和 茂, 田川 陽一, 町井 研士, 柴田 進和, 岩倉 洋一郎

日本臨床免疫学会会誌   ( 26回抄録集 )   183 - 183   1998.10

マウスコロナウイルス感染に対するIFN-γ欠損マウスの感受性のマウス系統差

久和 茂, 河村 清次, 田川 陽一, 町井 研士, 柴田 進和, 土井 邦雄, 吉川 泰弘, 岩倉 洋一郎

日本獣医学会学術集会講演要旨集   126回   60 - 60   1998.8

EXTRAORDINARILY STABLE MINI-HAIRPINS - ELECTROPHORETICAL AND THERMAL-PROPERTIES OF THE VARIOUS SEQUENCE VARIANTS OF D(GCGAAAGC) AND THEIR EFFECT ON DNA SEQUENCING

HIRAO, I, NISHIMURA, Y, TAGAWA, Y, WATANABE, K, MIURA, K

Nucleic Acids Research   20 ( 15 )   1992

2P-190 Observation of adhesion and extension of cell types various by QCM-D

Takeshita Yuji, Harimoto Kenichi, Tamai Miho, Minami Takayuki, Ogi Hirotsugu, Nagaoka Noriyuki, Matsukawa Akihiro, Yoshida Yasuhiro, Tagawa Yohichi

66   154 - 154   2014

1S-Ep04 Strategy for construction of minimal mammal in vitrosystem and its applications

Tagawa Yoh-ichi, Tamai Miho, Fujiyama Yoichi

66   16 - 16   2014

Embryonic stem cell-derived hepatic tissue micro-culture system

AHN Sungho, TAMAI Miho, TOYODA Yu, OKUYAMA Hisashi, AKAIKE Toshihiro, SHINDO Takayuki, FUJIYAMA Yoichi, OZEKI Eiichi, TAGAWA Yoh-ichi

14   1035 - 1035   2009.12

OE-237 Deficiency of Tumour Necrosis Factor-alpha and Interferon-gamma in Bone Marrow Cells Synergistically Inhibits Neointimal Formation following Vascular Injury(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Murayama Hideki, Takahashi Masafumi, Shiba Yuji, Ise Hirohiko, Takamoto Masaya, Tagawa Yoh-ichi, Iwakura Yoichirou, Ikeda Uichi

Circulation journal : official journal of the Japanese Circulation Society   73   234 - 234   2009.3

Role of Interleukin-6 and its Crosstalk with AT1R in Acute and Chronic Rejection of Murine Cardiac Allografts

Atsushi Izawa, Masafumi Takahashi, Hlrohiko Ise, Hajime Morimoto, Noriyuld Yajima, Yoh-ichi Tagawa, Yoichiro Iwakura, Uichi Ikeda

CIRCULATION   118 ( 18 )   S1015 - S1015   2008.10

Biomaterial technology for embryonic stem cell research : super liver model having high performance and multiple hepatic functions

TAGAWA Yoh-ichi

Journal of Japanese Society for Biomaterials   26 ( 4 )   325 - 329   2008.7

Interleukin-6 blockade attenuates the development of both acute and chronic rejection of murine cardiac allografts: A potential crosstalk between interleukin-6 and signaling through angiotensin II type 1 receptor.

Atsushi Izawa, Masafumi Takahashi, Hirohiko Ise, Hajime Morimoto, Noriyuki Yajima, Yoh-Ichi Tagawa, Yoichiro Iwakura, Uichi Ikeda

AMERICAN JOURNAL OF TRANSPLANTATION   7   426 - 426   2007.5

PE-269 Critical Role of Interleukin-6 and its Crosstalk with AT1R Signaling in Acute Rejection of Murine Cardiac Allografts(Transplantation/LVAD-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Izawa Atsushi, Takahashi Masafumi, Ise Hirohiko, Morimoto Hajime, Yajima Noriyuki, Tagawa Yoh-ichi, Iwakura Yoichiro, Ikeda Uichi

Circulation journal : official journal of the Japanese Circulation Society   71   392 - 392   2007.3

Effect of zinc on hepatoprotectivity of α1-acid glycoprotein

KAWASE Masaya, KAGAYA Noritaka, KAMIYOSHI Akiko, TAGAWA Yoh-ichi, YAGI Kiyohito

Biomedical research on trace elements   16 ( 4 )   299 - 301   2005.12

Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma

S Sehra, G Pynaert, K Tournoy, A Haegeman, P Matthys, Y Tagawa, R Pauwels, J Grooten

JOURNAL OF IMMUNOLOGY   171 ( 4 )   2080 - 2089   2003.8

Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants

K Johkura, L Cui, A Suzuki, RF Teng, A Kamiyoshi, S Okamura, S Kubota, Zhao, X, K Asanuma, Y Okouchi, N Ogiwara, Y Tagawa, K Sasaki

CARDIOVASCULAR RESEARCH   58 ( 2 )   435 - 443   2003.5

IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response

S Nakae, Y Komiyama, S Narumi, K Sudo, R Horai, Y Tagawa, K Sekikawa, K Matsushima, M Asano, Y Iwakura

INTERNATIONAL IMMUNOLOGY   15 ( 2 )   251 - 260   2003.2

Differences between BALB/c and C57BL/6 mice in mouse hepatitis virus replication in primary hepatocyte culture

S Kyuwa, S Kawamura, Y Tagawa, Y Iwakura, T Urano, Y Yoshikawa

EXPERIMENTAL ANIMALS   52 ( 1 )   81 - 84   2003.1

IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response

Nakae, S, Komiyama, Y, Narumi, S, Sudo, K, Horai, R, Tagawa, Y, Sekikawa, K, Matsushima, K, Asano, M, Iwakura, Y

International Immunology   15 ( 2 )   251 - 260   2003

特集「発生工学」 分担執筆として、 ・田川陽一：特集によせて． ・小川真一郎、田川陽一：ＥＳ細胞を用いた再生医療

生物工学会誌   81   343 - 360   2003

Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants

Johkura, K, Cui, L, Suzuki, A, Teng, RF, Kamiyoshi, A, Okamura, S, Kubota, S, Zhao, X, Asanuma, K, Okouchi, Y, Ogiwara, N, Tagawa, Y, Sasaki, K

Cardiovascular Research   58 ( 2 )   435 - 443   2003

Differences between BALB/c and C57BL/6 mice in mouse hepatitis virus replication in primary hepatocyte culture

Kyuwa, S, Kawamura, S, Tagawa, Y, Iwakura, Y, Urano, T, Yoshikawa, Y

Experimental Animals   52 ( 1 )   81 - 84   2003

コンディショナル ノックアウトマウス

分子呼吸器病   7   59 - 62   2003

再生医療の展望：再生医学と胚性幹細胞.

信州医学雑誌   51   107 - 108   2003

再生医療の展望：再生医療と遺伝子工学―ＥＳ細胞の利用を例にー.

信州医学雑誌   51   361 - 362   2003

Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma

Sehra, S, Pynaert, G, Tournoy, K, Haegeman, A, Matthys, P, Tagawa, Y, Pauwels, R, Grooten, J

Journal of Immunology   171 ( 4 )   2080 - 2089   2003

Enhancing effect of zinc on hepatoprotectivity of epigallocatechin gallate in isolated rat hepatocytes

N Kagaya, M Kawase, H Maeda, YI Tagawa, H Nagashima, H Ohmori, K Yagi

BIOLOGICAL & PHARMACEUTICAL BULLETIN   25 ( 9 )   1156 - 1160   2002.9

Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes

M Mizuki, A Nakane, K Sekikawa, Y Tagawa, Y Iwakura

INFECTION AND IMMUNITY   70 ( 9 )   4805 - 4811   2002.9

Suppression of cytotoxin-induced cell death in isolated hepatocytes by tea catechins

N Kagaya, Y Tagawa, H Nagashima, R Saijo, M Kawase, K Yagi

EUROPEAN JOURNAL OF PHARMACOLOGY   450 ( 3 )   231 - 236   2002.8

Roles of gamma interferon and tumor necrosis factor-alpha in shiga toxin lethality

S Sasaki, K Omoe, Y Tagawa, Y Iwakura, K Sekikawa, K Shinagawa, A Nakane

MICROBIAL PATHOGENESIS   33 ( 1 )   43 - 47   2002.7

Acute hepatic failure in IFN-gamma-deficient BALB/c mice after murine coronavirus infection

S Kyuwa, S Shibata, Y Tagawa, Y Iwakura, K Machii, T Urano

VIRUS RESEARCH   83 ( 1-2 )   169 - 177   2002.2

Inhibition of B16 melanoma experimental metastasis by interferon-gamma through direct inhibition of cell proliferation and activation of antitumour host mechanisms

S Kakuta, Y Tagawa, S Shibata, M Nanno, Y Iwakura

IMMUNOLOGY   105 ( 1 )   92 - 100   2002.1

Acute hepatic failure in IFN-gamma-deficient BALB/c mice after murine coronavirus infection

Kyuwa, S, Shibata, S, Tagawa, Y, Iwakura, Y, Machii, K, Urano, T

Virus Research   83 ( 1-2 )   169 - 177   2002

Suppression of cytotoxin-induced cell death in isolated hepatocytes by tea catechins

Kagaya, N, Tagawa, Y, Nagashima, H, Saijo, R, Kawase, M, Yagi, K

European Journal of Pharmacology   450 ( 3 )   231 - 236   2002

Enhancing effect of zinc on hepatoprotectivity of epigallocatechin gallate in isolated rat hepatocytes

Kagaya, N, Kawase, M, Maeda, H, Tagawa, YI, Nagashima, H, Ohmori, H, Yagi, K

Biological & Pharmaceutical Bulletin   25 ( 9 )   1156 - 1160   2002

1138 Protection of hepatocytes from cytotoxin by a_1-acid glycoprotein

Akamatu Souichirou, Kagaya Noritaka, Oyagi Suguru, Tagawa Yoh-ichi, Kawase Masaya, Yagi Kiyohito

14   208 - 208   2002

1137 Enhancing effect of zinc on hepatoprotectivity of epigallocatechin gallate in isolated rat hepatocytes

Kagaya Noritaka, Akamatsu Soh-ichiro, Oyagi Suguru, Kawase Masaya, Yagi Kiyohito, Tagawa Yoh-ichi, Saijo Ryoyasu

14   208 - 208   2002

Inhibition of B16 melanoma experimental metastasis by interferon-gamma through direct inhibition of cell proliferation and activation of antitumour host mechanisms

Kakuta, S, Tagawa, Y, Shibata, S, Nanno, M, Iwakura, Y

Immunology   105 ( 1 )   92 - 100   2002

Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes

Mizuki, M, Nakane, A, Sekikawa, K, Tagawa, Y, Iwakura, Y

Infection and Immunity   70 ( 9 )   4805 - 4811   2002

Roles of gamma interferon and tumor necrosis factor-alpha in shiga toxin lethality

Sasaki, S, Omoe, K, Tagawa, Y, Iwakura, Y, Sekikawa, K, Shinagawa, K, Nakane, A

Microbial Pathogenesis   33 ( 1 )   43 - 47   2002

Effect of 6-hydroxydopamine on host resistance against Listeria monocytogenes infection

T Miura, T Kudo, A Matsuki, K Sekikawa, YI Tagawa, Y Iwakura, A Nakane

INFECTION AND IMMUNITY   69 ( 12 )   7234 - 7241   2001.12

A critical role of Fc receptor-mediated antibody-dependent phagocytosis in the host resistance to blood-stage Plasmodium berghei XAT infection

T Yoneto, S Waki, T Takai, Y Tagawa, Y Iwakura, J Mizuguchi, H Nariuchi, T Yoshimoto

JOURNAL OF IMMUNOLOGY   166 ( 10 )   6236 - 6241   2001.5

Organ infectivity of Toxoplasma gondii in interferon-gamma knockout mice

K Norose, HS Mun, F Aosai, M Chen, H Hata, Y Tagawa, Y Iwakura, A Yano

JOURNAL OF PARASITOLOGY   87 ( 2 )   447 - 452   2001.4

The severity of hepatic lesion after intraperitoneal JHMV infection in IFN-gamma deficient mice is parallel to viral replication in hepatocytes in vitro

Kyuwa, S, Kawamura, S, Shibata, S, Machii, K, Tagawa, YI, Iwakura, Y, Urano, T, Lavi, E, Weiss, SR, Hingley, ST

Nidoviruses (Coronaviruses and Arteriviruses)   494   95 - 99   2001

A critical role of Fc receptor-mediated antibody-dependent phagocytosis in the host resistance to blood-stage Plasmodium berghei XAT infection

Yoneto, T, Waki, S, Takai, T, Tagawa, Y, Iwakura, Y, Mizuguchi, J, Nariuchi, H, Yoshimoto, T

The Journal of Immunology   166 ( 10 )   6236 - 6241   2001

Organ infectivity of Toxoplasma gondii in interferon-gamma knockout mice

Norose, K, Mun, HS, Aosai, F, Chen, M, Hata, H, Tagawa, Y, Iwakura, Y, Yano, A

Journal of Parasitology   87 ( 2 )   447 - 452   2001

The severity of hepatic lesion after intraperitoneal JHMV infection in IFN-gamma deficient mice is parallel to viral replication in hepatocytes in vitro

S Kyuwa, S Kawamura, S Shibata, K Machii, YI Tagawa, Y Iwakura, T Urano

NIDOVIRUSES (CORONAVIRUSES AND ARTERIVIRUSES)   494   95 - 99   2001

P69 Analysis of genetically controlled organ-specific infectivity of Toxoplasma gondii by using IFN-γ KO mice and parabiosed rat

NOROSE Kazumi, YANO Akihiko, AOSAI Fumie, HATA Hidekazu, MUN Hye-Seong, CHEN Mei, KOBAYASHI Masashi, RIKIHISA Naoaki, TAGAWA Yohichi, IWAKURA Yohichiroh

Med. Entomol. Zool.   52 ( 0 )   95 - 95   2001

Effect of 6-hydroxydopamine on host resistance against Listeria monocytogenes infection

Miura, T, Kudo, T, Matsuki, A, Sekikawa, K, Tagawa, YI, Iwakura, Y, Nakane, A

Infection and Immunity   69 ( 12 )   7234 - 7241   2001

Toxoplasma gandii Hsp70 as a danger signal in Toxoplasma gondii-infected mice

HS Mun, F Aosai, K Norose, M Chen, H Hata, Y Tagawa, Y Iwakura, DS Byun, A Yano

CELL STRESS & CHAPERONES   5 ( 4 )   328 - 335   2000.10

Roles of endogenous cytokines in liver apoptosis of mice in lethal Listeria monocytogenes infection

T Miura, S Nishikawa, S Sasaki, K Yamada, S Hasegawa, D Mizuki, M Mizuki, Hatayama, I, K Sekikawa, Y Tagawa, Y Iwakura, A Nakane

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY   28 ( 4 )   335 - 341   2000.8

Hematological characteristics of rats spontaneously developing eosinophilia

K Matsumoto, N Matsushita, H Tomozawa, Y Tagawa

EXPERIMENTAL ANIMALS   49 ( 3 )   211 - 215   2000.7

Lipopolysaccharide-induced HIV-1 expression in transgenic mice is mediated by tumor necrosis factor-alpha and interleukin-1, but not by interferon-gamma nor interleukin-6

J Tanaka, H Ozaki, J Yasuda, R Horai, Y Tagawa, M Asano, S Saijo, M Imai, K Sekikawa, M Kopf, Y Iwakura

AIDS   14 ( 10 )   1299 - 1307   2000.7

Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon

S Sasaki, S Nishikawa, T Miura, M Mizuki, K Yamada, H Madarame, Y Tagawa, Y Iwakura, A Nakane

INFECTION AND IMMUNITY   68 ( 5 )   2424 - 2430   2000.5

Interferon gamma priming is not critical for IL-12 production of murine spleen cells

A Hino, O Igarashi, Y Tagawa, Y Iwakura, H Nariuchi

CYTOKINE   12 ( 1 )   12 - 20   2000.1

Bimodal role of endogenous interleukin-6 in concanavalin A-induced hepatitis in mice

YI Tagawa, P Matthys, H Heremans, C Dillen, Z Zaman, Y Iwakura, A Billiau

JOURNAL OF LEUKOCYTE BIOLOGY   67 ( 1 )   90 - 96   2000.1

Roles of endogenous cytokines in liver apoptosis of mice in lethal Listeria monocytogenes infection

Miura, T, Nishikawa, S, Sasaki, S, Yamada, K, Hasegawa, S, Mizuki, D, Mizuki, M, Hatayama, I, Sekikawa, K, Tagawa, Y, Iwakura, Y, Nakane, A

Fems Immunology and Medical Microbiology   28 ( 4 )   335 - 341   2000

Bimodal role of endogenous interleukin-6 in concanavalin A-induced hepatitis in mice

Tagawa, YI, Matthys, P, Heremans, H, Dillen, C, Zaman, Z, Iwakura, Y, Billiau, A

Journal of Leukocyte Biology   67 ( 1 )   90 - 96   2000

Lipopolysaccharide-induced HIV-1 expression in transgenic mice is mediated by tumor necrosis factor-alpha and interleukin-1, but not by interferon-gamma nor interleukin-6

Tanaka, J, Ozaki, H, Yasuda, J, Horai, R, Tagawa, Y, Asano, M, Saijo, S, Imai, M, Sekikawa, K, Kopf, M, Iwakura, Y

Aids   14 ( 10 )   1299 - 1307   2000

Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon

Sasaki, S, Nishikawa, S, Miura, T, Mizuki, M, Yamada, K, Madarame, H, Tagawa, Y, Iwakura, Y, Nakane, A

Infection and Immunity   68 ( 5 )   2424 - 2430   2000

Hematological characteristics of rats spontaneously developing eosinophilia

Matsumoto, K, Matsushita, N, Tomozawa, H, Tagawa, Y

Experimental Animals   49 ( 3 )   211 - 215   2000

Toxoplasma gandii Hsp70 as a danger signal in Toxoplasma gondii-infected mice

Mun, HS, Aosai, F, Norose, K, Chen, M, Hata, H, Tagawa, Y, Iwakura, Y, Byun, DS, Yano, A

Cell Stress & Chaperones   5 ( 4 )   328 - 335   2000

Interferon gamma priming is not critical for IL-12 production of murine spleen cells

Hino, A, Igarashi, O, Tagawa, Y, Iwakura, Y, Nariuchi, H

Cytokine   12 ( 1 )   12 - 20   2000

Generation of polymeric immunoglobulin receptor-deficient mouse with marked reduction of secretory IgA

S Shimada, M Kawaguchi-Miyashita, A Kushiro, T Sato, M Nanno, T Sako, Y Matsuoka, K Sudo, Y Tagawa, Y Iwakura, M Ohwaki

JOURNAL OF IMMUNOLOGY   163 ( 10 )   5367 - 5373   1999.11

Toxoplasma gondii: Difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-gamma in mice inoculated with the cysts perorally

M Kobayashi, F Aosai, H Hata, HS Mun, Y Tagawa, Y Iwakura, A Yano

JOURNAL OF PARASITOLOGY   85 ( 5 )   973 - 975   1999.10

Roles of CD4+ T cells and gamma interferon in protective immunity against Babesia microti infection in mice

Igarashi, I, R Suzuki, S Waki, Y Tagawa, S Seng, S Tum, Y Omata, A Saito, H Nagasawa, Y Iwakura, N Suzuki, T Mikami, Y Toyoda

INFECTION AND IMMUNITY   67 ( 8 )   4143 - 4148   1999.8

IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor

Y Hyodo, K Matsui, N Hayashi, H Tsutsui, S Kashiwamura, H Yamauchi, K Hiroishi, K Takeda, Y Tagawa, Y Iwakura, N Kayagaki, M Kurimoto, H Okamura, T Hada, H Yagita, S Akira, K Nakanishi, K Higashino

JOURNAL OF IMMUNOLOGY   162 ( 3 )   1662 - 1668   1999.2

Role of gamma interferon in Helicobacter pylori-induced gastric inflammatory responses in a mouse model

N Sawai, M Kita, T Kodama, T Tanahashi, Y Yamaoka, YI Tagawa, Y Iwakura, J Imanishi

INFECTION AND IMMUNITY   67 ( 1 )   279 - 285   1999.1

Involvement of autoimmunity against type II collagen in the development of arthritis in mice transgenic for the human T cell leukemia virus type I tax gene

M Kotani, Y Tagawa, Y Iwakura

EUROPEAN JOURNAL OF IMMUNOLOGY   29 ( 1 )   54 - 64   1999.1

Alleviation of lipopolysaccharide-induced acute liver injury in Propionibacterium acnes-primed IFN-gamma-deficient mice by a concomitant reduction of TNF-alpha, IL-12, and IL-18 production

H Tsuji, N Mukaida, A Harada, S Kaneko, E Matsushita, Y Nakanuma, H Tsutsui, H Okamura, K Nakanishi, Y Tagawa, Y Iwakura, K Kobayashi, K Matsushima

JOURNAL OF IMMUNOLOGY   162 ( 2 )   1049 - 1055   1999.1

Toxoplasma gondii: Difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-gamma in mice inoculated with the cysts perorally

Kobayashi, M, Aosai, F, Hata, H, Mun, HS, Tagawa, Y, Iwakura, Y, Yano, A

Journal of Parasitology   85 ( 5 )   973 - 975   1999

Interferon-gamma-dependent/independent expression of indoleamine 2,3-dioxygenase - Studies with interferon-gamma-knockout mice

O Takikawa, Y Tagawa, Y Iwakura, R Yoshida, RJW Truscott

TRYPTOPHAN, SEROTONIN AND MELATONIN   467   553 - 557   1999

トランスジェニック動物とノックアウト動物.

信州医学雑誌   47   445 - 446   1999

IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor

Hyodo, Y, Matsui, K, Hayashi, N, Tsutsui, H, Kashiwamura, S, Yamauchi, H, Hiroishi, K, Takeda, K, Tagawa, Y, Iwakura, Y, Kayagaki, N, Kurimoto, M, Okamura, H, Hada, T, Yagita, H, Akira, S, Nakanishi, K, Higashino, K

Journal of Immunology   162 ( 3 )   1662 - 1668   1999

Alleviation of lipopolysaccharide-induced acute liver injury in Propionibacterium acnes-primed IFN-gamma-deficient mice by a concomitant reduction of TNF-alpha, IL-12, and IL-18 production

Tsuji, H, Mukaida, N, Harada, A, Kaneko, S, Matsushita, E, Nakanuma, Y, Tsutsui, H, Okamura, H, Nakanishi, K, Tagawa, Y, Iwakura, Y, Kobayashi, K, Matsushima, K

Journal of Immunology   162 ( 2 )   1049 - 1055   1999

Role of gamma interferon in Helicobacter pylori-induced gastric inflammatory responses in a mouse model

Sawai, N, Kita, M, Kodama, T, Tanahashi, T, Yamaoka, Y, Tagawa, YI, Iwakura, Y, Imanishi, J

Infection and Immunity   67 ( 1 )   279 - 285   1999

Kinetics of cytokine production in the cornea and trigeminal ganglion of C57BL/6 mice after corneal HSV-1 infection

He, JC, Ichimura, H, Iida, T, Minami, M, Kobayashi, K, Kita, M, Sotozono, C, Tagawa, YI, Iwakura, Y, Imanishi, J

Journal of Interferon and Cytokine Research   19 ( 6 )   609 - 615   1999

Interferon-gamma-dependent/independent expression of indoleamine 2,3-dioxygenase - Studies with interferon-gamma-knockout mice

Takikawa, O, Tagawa, Y, Iwakura, Y, Yoshida, R, Truscott, RJW, Huether, G, Kochen, W, Simat, TJ, Steinhart, H

Tryptophan, Serotonin and Melatonin   467   553 - 557   1999

Involvement of autoimmunity against type II collagen in the development of arthritis in mice transgenic for the human T cell leukemia virus type I tax gene

Kotani, M, Tagawa, Y, Iwakura, Y

European Journal of Immunology   29 ( 1 )   54 - 64   1999

Generation of polymeric immunoglobulin receptor-deficient mouse with marked reduction of secretory IgA

Shimada S, Kawaguchi-Miyashita M, Kushiro A, Sato T, Nanno M, Sako T, Matsuoka Y, Sudo K, Tagawa Y, Iwakura Y, Ohwaki M

The Journal of Immunology   163 ( 10 )   5367 - 5373   1999

Roles of CD4+ T cells and gamma interferon in protective immunity against Babesia microti infection in mice

Igarashi, I, Suzuki, R, Waki, S, Tagawa, Y, Seng, S, Tum, S, Omata, Y, Saito, A, Nagasawa, H, Iwakura, Y, Suzuki, N, Mikami, T, Toyoda, Y

Infection and Immunity   67 ( 8 )   4143 - 4148   1999

Kinetics of cytokine production in the cornea and trigeminal ganglion of C57BL/6 mice after corneal HSV-1 infection

He, JC, Ichimura, H, Iida, T, Minami, M, Kobayashi, K, Kita, M, Sotozono, C, Tagawa, YI, Iwakura, Y, Imanishi, J

Journal of Interferon & Cytokine Research   19 ( 6 )   609 - 615   1999

Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis

Y Tagawa, S Kakuta, Y Iwakura

EUROPEAN JOURNAL OF IMMUNOLOGY   28 ( 12 )   4105 - 4113   1998.12

ノックアウトマウスを用いたIFN-γの抗腫瘍作用の解析

角田 茂, 田川 陽一, 柴田 進和, 南野 昌信, 岩倉 洋一郎

日本臨床免疫学会会誌   ( 26回抄録集 )   103 - 103   1998.10

Induction of granulomas in interferon-gamma gene-disrupted mice by avirulent but not by virulent strains of Mycobacterium tuberculosis

Sugawara, I, H Yamada, Y Kazumi, N Doi, K Otomo, T Aoki, S Mizuno, T Udagawa, Y Tagawa, Y Iwakura

JOURNAL OF MEDICAL MICROBIOLOGY   47 ( 10 )   871 - 877   1998.10

Development of rheumatoid-like chronic inflammatory arthropathy in HTLV-1 transgenic mice is suppressed by the deficiency of IL-1 or IL-6, but not IFN-G, IL-4, nor TNF-alpha

Y Iwakura, K Habu, M Kotani, R Horai, M Asano, Y Tagawa, C Ishitsuka, S Saijo

EUROPEAN CYTOKINE NETWORK   9 ( 3 )   409 - 409   1998.9

Relationships between IFN-gamma and IL-4 in the development of T-cell mediated hepatitis in mice.

Y Tagawa, P Matthys, Z Zaman, S Kakuta, Y Iwakura, A Billiau

EUROPEAN CYTOKINE NETWORK   9 ( 3 )   543 - 543   1998.9

ノックアウトマウスを用いたIFN-γの抗腫瘍作用の解析

角田 茂, 田川 陽一, 南野 昌信, 岩倉 洋一郎

日本癌学会総会記事   57回   190 - 190   1998.8

Cutting edge: CD40 ligation prevents neonatal induction of transplantation tolerance

Flamand, V, Donckier, V, FX Demoor, A Le Moine, P Matthys, ML Vanderhaeghen, Y Tagawa, Y Iwakura, A Billiau, D Abramowicz, M Goldman

JOURNAL OF IMMUNOLOGY   160 ( 10 )   4666 - 4669   1998.5

マウスコロナウイルス感染に対するIFN-γ欠損マウスの感受性のマウス系統差

久和茂, 田川陽一, 町井研士, 柴田進和, 岩倉洋一郎

日本免疫学会総会・学術集会記録   28   1998

MHV-induced fatal peritonitis in mice lacking IFN-gamma

S Kyuwa, Y Tagawa, K Machii, S Shibata, K Doi, K Fujiwara, Y Iwakura

CORONAVIRUSES AND ARTERIVIRUSES   440   445 - 450   1998

Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis

Tagawa, Y, Kakuta, S, Iwakura, Y

European Journal of Immunology   28 ( 12 )   4105 - 4113   1998

Murine coronavirus-induced subacute fatal peritonitis in C57BL/6 mice deficient in gamma interferon

Kyuwa, S, Tagawa, YI, Shibata, S, Doi, K, Machii, K, Iwakura, Y

Journal of Virology   72 ( 11 )   9286 - 9290   1998

Cutting edge: CD40 ligation prevents neonatal induction of transplantation tolerance

Flamand, V, Donckier, V, Demoor, FX, Le Moine, A, Matthys, P, Vanderhaeghen, ML, Tagawa, Y, Iwakura, Y, Billiau, A, Abramowicz, D, Goldman, M

Journal of Immunology   160 ( 10 )   4666 - 4669   1998

Induction of granulomas in interferon-gamma gene-disrupted mice by avirulent but not by virulent strains of Mycobacterium tuberculosis

Sugawara, I, Yamada, H, Kazumi, Y, Doi, N, Otomo, K, Aoki, T, Mizuno, S, Udagawa, T, Tagawa, Y, Iwakura, Y

Journal of Medical Microbiology   47 ( 10 )   871 - 877   1998

MHV-induced fatal peritonitis in mice lacking IFN-gamma

Kyuwa S, Tagawa Y, Machii K, Shibata S, Doi K, Fujiwara K, Iwakura Y

Advances in Experimental Medicine and Biology   440   445 - 450   1998

Role of IFN-.GAMMA. and IL-12 in Staphylococcus aureus infection.

佐々木早苗, 三浦富智, 平末麻唯子, 山田恭吾, 長谷川傑, 水木大介, 田川陽一, 岩倉洋一郎, 中根明夫

日本免疫学会総会・学術集会記録   27   268   1997.10

Cytokine response in Listeriolysin O lacking variant infection.

三浦富智, 山田恭吾, 佐々木早苗, 平末麻唯子, 長谷川傑, 水木大介, 田川陽一, 岩倉洋一郎, 中根明夫

日本免疫学会総会・学術集会記録   27   268   1997.10

Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice - Role for IFN-gamma in activating apoptosis of hepatocytes

Y Tagawa, K Sekikawa, Y Iwakura

JOURNAL OF IMMUNOLOGY   159 ( 3 )   1418 - 1428   1997.8

Experimental model with Helicobacter pylori infection in C57BL/6 mice

N Sawai, M Kita, Y Yamaoka, T Tanahashi, T Kodama, K Kashima, Y Tagawa, Y Iwakura, J Imanishi

GASTROENTEROLOGY   112 ( 4 )   A280 - A280   1997.4

Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells

T Yoshimoto, H Okamura, YI Tagawa, Y Iwakura, K Nakanishi

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   94 ( 8 )   3948 - 3953   1997.4

IL-18 together with IL-12 inhibits IgE synthesis by induction of IFN gamma production from activated B cells.

T Yoshimoto, H Okamura, Y Tagawa, Y Iwakura, K Nakanishi

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   99 ( 1 )   1894 - 1894   1997.1

Subacute peritonitis of an IFN-.GAMMA. knockout mouse by mouse hepatitis virus infection.

久和茂, 田川陽一, 町井研士, 柴田進和, 土井邦雄, 岩倉洋一郎

日本獣医学会学術集会講演要旨集   124th   1997

Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice - Role for IFN-gamma in activating apoptosis of hepatocytes

Tagawa, Y, Sekikawa, K, Iwakura, Y

Journal of Immunology   159 ( 3 )   1418 - 1428   1997

Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells

Yoshimoto, T, Okamura, H, Tagawa, YI, Iwakura, Y, Nakanishi, K

Proceedings of the National Academy of Sciences of the United States of America   94 ( 8 )   3948 - 3953   1997

IFN-γ欠損マウスにおけるインド-ルアミン酸素添加酵素活性

滝川 修, 刀禰 重信, 田川 陽一, 岩倉 洋一郎, 吉田 龍太郎

日本分子生物学会年会プログラム・講演要旨集   19   338 - 338   1996.8

IFN-γノックアウトマウスを用いたCon A誘導肝炎の解析

田川 陽一, 岩倉 洋一郎

日本分子生物学会年会プログラム・講演要旨集   19   338 - 338   1996.8

HTLV-Iトランスジェニックマウスを用いた慢性関節炎発症機構の解析

西城 忍, 板垣 経子, 小谷 素子, 田川 陽一, 浅野 雅秀, 岩倉 洋一郎

日本分子生物学会年会プログラム・講演要旨集   19   346 - 346   1996.8

Role of interferon - .GAMMA. in mouse hepatitis virus infection.

久和茂, 田川陽一, 町井研士, 柴田進和, 土井邦雄, 岩倉洋一郎

日本獣医学会学術集会講演要旨集   122nd   1996

Mouse hepatitis virus infection in IFN -.GAMMA. knockout mouse.

久和茂, 田川陽一, 町井研士, 柴田進和, 土井邦雄, 岩倉洋一郎

日本免疫学会総会・学術集会記録   26   1996

Development and pharmacokinetic application of an intestine and liver in vitro model derived from ES/iPS cells

Grant number：25242040  2013.4 - 2017.3

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

Tagawa Yoh-ichi, FUJIYAMA Yoichi

Analysis of the role of Pdx-1 gene in liver progenitor cells during liver regeneration and carcinogenesis.

Grant number：25430086  2013.4 - 2016.3

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

KOIKE Toru, SHIOJIRI Nobuyoshi, TAGAWA Yoh-ichi, ABE Naohiro, SUENAGA Koudai, Yamauchi Masashi

Construction of in vitro sytem of metabolism-associated organs and tissues

Grant number：24650254  2012.4 - 2014.3

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

TAGAWA Yoh-ichi, FUJIYAMA Yoichi

Construction of hepatic tissue model by developing synthetic biological systems

Grant number：23119003  2011.4 - 2016.3

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Tagawa Yoh-ichi, MIYAGAWA Shinichi

Synthetic Biology for the Comprehension of Biomolecular Networks

Grant number：23119001  2011.4 - 2016.3

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

OKAMOTO MASAHIRO, Hanai Taizo, Tagawa Yoichi, Tsuge Kenji, Kiga Daisuke, Rondelez Yannick, Suyama Akira, Yamamura Masayuki, Iba Hitoshi

Generating artificial parenchymal and hollow organs fabricated with collagen fibrils,various cells, and cytokines using a bioreactor that we have developed

Grant number：22300167  2010 - 2012

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

ADACHI Eijiro, AKAIKE Toshihiro, TAGAWA Youichi, NISHIYAMA Toshio, MATSUSHITA Osamu, HATTORI Masakazu

Construction of in vitro liver model using ES, iPS, or somatic stem cells, and its application for drug metabolism assay

Grant number：21300178  2009 - 2011

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

TAGAWA Yoh-ichi, OZEKI Eiichi, MIYAGAWA Shinichi

Generating transplantable artificial tissues composed of collagen fibrils and cells using a newly designed bioreactor

Grant number：19300174  2007 - 2009

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

ADACHI Eijiro, NISHIYAMA Toshio, TAGAWA Yoh-Ichi

The verification for plasticity of hepatic stem cell by using functional analysis of embryonic stem cell and organ-specific stem cell

Grant number：19591580  2007 - 2008

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

MIYAGAWA Shin-ichi, MIWA Siroh, TAGAWA Yoh-ichi, MARUTA Hukuto, TAGAWA Yoh-ichi

Development of super functional liver model based on developmental information

Grant number：18300161  2006 - 2008

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

TAGAWA Yoh-ichi, OZEKI Eiichi, MIYAGAWA Shinichi, NAGAOKA Masato

Establishment of Information Basis for Tooth Regeneration

Grant number：17209062  2005 - 2008

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

KUBOKI Takuo, UEDA Minoru, KANYAMA Manabu, TAKASHIBA Syogo, TSUJI Takashi, TAKIGAWA Masaharu, ASAHAR Hiroshi, TUCHIMOTO Youhei, SONOYAMA Wataru, TAGAWA Youichi

チタン表面への生体分子および細胞接着挙動のナノレベル・2次元・リアルタイム測定

Grant number：16659533  2004 - 2005

日本学術振興会  科学研究費助成事業  萌芽研究

吉田 靖弘, 鈴木 一臣, 窪木 拓男, 平田 伊左雄, 田川 陽一, 長岡 紀幸

Development of functional Ti implants with release of growth factors

Grant number：16390557  2004 - 2005

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

YOSHIDA Yasuhiro, SUZUKI Kazuomi, KUBOKI Takuo, HIRATA Isao, TAGAWA Yoh-ichi, NAGAOKA Noriyuki

肝臓の再生医学研究のためのモデル動物の開発とES細胞を用いた肝細胞の再生

Grant number：15700314  2003 - 2005

日本学術振興会  科学研究費助成事業  若手研究(B)

田川 陽一

Study on cardio-creation using vessels circumvalated by fetal or ES cell-derived cardiac tissues and their application for cardiac diseases

Grant number：13558107  2001 - 2003

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

AMANO Jun, JOHKURA Kohei, TAGAWA Yo-ichi, AMANO Jun

Establishment of a new inbred strain rat developing spontaneous eosinohilia (MES) and investigation of the pathogenesis.

Grant number：12680808  2000 - 2002

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

MATSUMOTO Kiyoshi, TAGAWA Yoich, TAKAMOTO Masaya

発生工学的手法を応用IFN-γおよびIL-6の肝炎における役割の解析

Grant number：11780603  1999 - 2000

日本学術振興会  科学研究費助成事業  奨励研究(A)

田川 陽一

サイトカイン研究のための遺伝子改変マウスライブラリーの作製

Grant number：08408037  1996 - 1998

日本学術振興会  科学研究費助成事業  基盤研究(A)

岩倉 洋一郎, 須藤 カツ子, 浅野 雅秀, 松澤 昭雄, 田川 陽一

標的遺伝子組み換え法によるサイトカインの炎症反応における役割の解析

Grant number：08252203  1996

日本学術振興会  科学研究費助成事業  重点領域研究

岩倉 洋一郎, 田川 陽一, 浅野 雅秀

遺伝子改変マウスを用いたインターフェロンの生理機能の解析

Grant number：08780798  1996

日本学術振興会  科学研究費助成事業  奨励研究(A)

田川 陽一

ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析

Grant number：08282212  1996

日本学術振興会  科学研究費助成事業  重点領域研究

岩倉 洋一郎, 田川 陽一, 浅野 雅秀

遺伝子改変マウスを用いたインターフェロンの生理機能解析

Grant number：07780751  1995

日本学術振興会  科学研究費助成事業  奨励研究(A)

田川 陽一

標的遺伝子組み換え法を用いたサイトカインの生理機能の解析

Grant number：07260204  1995

日本学術振興会  科学研究費助成事業  重点領域研究

岩倉 洋一郎, 田川 陽一, 浅野 雅秀

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