Organization
Institute of Integrated Research Research Center for Autonomous Systems Materialogy Specially Appointed Junior Associate Professor
Title
Specially Appointed Junior Associate Professor
External link
SUGAI HIROKA
Degree
-
Doctor of Science ( 2018.3 Tohoku University )
Research Areas
-
Nanotechnology/Materials / Analytical chemistry
-
Nanotechnology/Materials / Bio chemistry
Education
-
Tohoku University Graduate School of Science Department of Chemistry
2015.4 - 2018.3
-
Tohoku University Graduate School of Science Department of Chemistry
2013.4 - 2015.3
-
Tohoku University Faculty of Science Department of Chemistry
2009.4 - 2013.3
Research History
-
Institute of Science Tokyo Institute of Integrated Research Specially Appointed Assistant Professor
2024.10
-
Tokyo Institute of Technology Institute of Innovative Research Specially Appointed Assistant Professor
2024.4 - 2024.9
-
Tokyo Institute of Technology International Research Frontiers Initiative Specially Appointed Assistant Professor
2022.12 - 2024.3
-
University of Tsukuba Faculty of Pure and Applied Sciences Assistant Professor
2021.3 - 2022.11
-
National Institute of Advanced Industrial Science and Technology Health and Medical Research Institute Research Fellow
2020.4 - 2021.2
-
National Institute of Advanced Industrial Science and Technology Biomedical Research Institute Postdoctoral fellow
2018.4 - 2020.3
-
Japan Society for the Promotion of Science Research Fellow
2016.4 - 2018.3
Professional Memberships
-
The Japan Society for Analytical Chemistry
-
The Biophysical Society of Japan
-
The Chemical Society of Japan
Papers
-
Emergence of Anisotropic Subcompartments via Coassembly of Hierarchically Ordered G-Quadruplexes and Fluid Polylysine in Droplet-Based Compartments Reviewed
Hiroka Sugai, Shunsuke Tomita, Mariko Toyoda, Kota Watanuki, Mao Fukuyama, Takashi Kajitani, Kazushi Kinbara
ACS Nano 2026.4
-
Reproducible Fabrication of a Chamber for Birefringence Imaging: Experimental Test with Temperature-Controlled Liquid-Crystalline DNA Assemblies
Hiroka Sugai, Kota Watanuki, Mariko Toyoda, Ayaka Yamazaki, Natsuki Yoshida, Shingo Maeda, Hiroaki Ando, Shogo Hamada, Kazushi Kinbara
2026.2
-
Effect of PEG Chain Length on the Water Solubility of Monodisperse PEG-Appended Molecules
Rei Hamaguchi, Ai Kohata, Mafumi Hishida, Hiroka Sugai, Mitsunori Ikeguchi, Kazushi Kinbara
2026.1
-
Elucidation of the Mutual Solubility of Amino Acids for the Rational Control of Phase-Separating Sequences Reviewed
Akira Nomoto, Hiroka Sugai, Kentaro Shiraki, Shunsuke Tomita
The Journal of Physical Chemistry B 129 ( 28 ) 7099 - 7107 2025.7
-
Masahiro Mimura, Hiroka Sugai, Tomoshi Kameda, Ryo Kitahara, Soichiro Kitazawa, Yoichi Shinkai, Ryoji Kurita, Shunsuke Tomita
2024.10
-
Chemical Tongues as Multipurpose Bioanalytical Tools for the Characterization of Complex Biological Samples Invited Reviewed
Shunsuke Tomita, Hiroka Sugai
Biophysics and Physicobiology 21 ( 3 ) e210017 2024.9
-
Miki Mori, Hiroka Sugai, Kohei Sato, Asuki Okada, Takashi Matsuo, Kazushi Kinbara
Chemical Communications 60 ( 62 ) 7979 - 7982 2024.8
-
Nanako Sakakibara, Tomoto Ura, Tsutomu Mikawa, Hiroka Sugai, Kentaro Shiraki
Soft Matter 19 ( 25 ) 4642 - 4650 2023.6
-
Junya Adachi, Haruka Oda, Toshiaki Fukushima, Beni Lestari, Hiroshi Kimura, Hiroka Sugai, Kentaro Shiraki, Rei Hamaguchi, Kohei Sato, Kazushi Kinbara
Analytical Chemistry 95 ( 12 ) 5196 - 5204 2023.3
-
Phase-Separation Propensity of Non-ionic Amino Acids in Peptide-Based Complex Coacervation Systems Reviewed
Yuto Akahoshi, Hiroka Sugai, Masahiro Mimura, Yoichi Shinkai, Ryoji Kurita, Kentaro Shiraki, Shunsuke Tomita
Biomacromolecules 24 ( 2 ) 704 - 713 2023.1
-
Damage-Free Evaluation of Cultured Cells Based on Multivariate Analysis with a Single-Polymer Probe Reviewed
Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihar, Kentaro Shirakia, Ryoji Kurita
Chemical Communications 58 ( 79 ) 11083 - 11086 2022.10
-
Masahiro Mimura, Shunsuke Tomita, Hiroka Sugai, Yoichi Shinkai, Sayaka Ishihara, Ryoji Kurita
Frontiers in Cell and Developmental Biology 9 710729 2021.8
-
Shunsuke Tomita, Hiroka Sugai, Sayaka Ishihara, Takuya Hosokai, Ryoji Kurita
Chemistry Letters 49 ( 12 ) 1447 - 1451 2020.12
-
Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihara, Kyoko Yoshioka, Ryoji Kurita
Analytical Chemistry 92 ( 22 ) 14939 - 14946 2020.10
-
Mari Okada, Hiroka Sugai, Shunsuke Tomita, Ryoji Kurita
Sensors 20 ( 18 ) 5110 - 5110 2020.9
-
Hiroka Sugai, Shunsuke Tomita, Ryoji Kurita
Analytical Sciences 36 ( 8 ) 923 - 934 2020.8
-
Shunsuke Tomita, Hiroka Sugai, Masahiro Mimura, Sayaka Ishihara, Kentaro Shiraki, Ryoji Kurita
ACS Applied Materials & Interfaces 11 ( 50 ) 47428 - 47436 2019.12
-
Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihara, Ryoji Kurita
ACS Sensors 4 ( 4 ) 827 - 831 2019.4
-
Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihara, Ryoji Kurita
Sensors and Materials 31 ( 1 ) 1 - 11 2019.1
-
Hiroka Sugai, Ikuhiko Nakase, Seiji Sakamoto, Akihiro Nishio, Masahito Inagaki, Masak Nishijimai, Asako Yamayoshi, Yasuyuki Araki, Satoru Ishibashi, Takanori Yokota, Yoshihisa Inoue, Takehiko Wada
Chemistry Letters 47 ( 3 ) 381 - 384 2018.3
-
Ryohei Uematsu, Masahito Inagaki, Mitsuo Asai, Hiroka Sugai, Yoshiki Maeda, Akira Nagami, Hirofumi Sato, Seiji Sakamoto, Yasuyuki Araki, Masaki Nishijima, Yoshihisa Inoue, Takehiko Wada
Chemistry Letters 45 ( 3 ) 350 - 352 2016.3
Books
-
界面制御による革新的生体適合性材料の開発最前線
冨田 峻介, 菅井 祥加（ Role： Contributor合成高分子–生体分子間の相互作用メカニズム：多点相互作用を基盤とする認識原理）
高井 まどか, 三浦 佳子 監修, エヌ・ティー・エス, 2025.12 （ ISBN:9784860437824 ）
-
相分離生物学の全貌
菅井 祥加, 冨田 峻介（ Role： Contributor特徴パターンの認識）
白木 賢太郎編, 東京化学同人 2020.11 （ ISBN:9784807913466 ）
MISC
-
On-chip Sensing Technology; Micro Bio Sensing Invited
Ryoji KURITA, Hiroka SUGAI, Syunsuke TOMITA
The Journal of The Institute of Electrical Engineers of Japan 144 ( 4 ) 205 - 208 2024.4
-
Characterization of cell culture media by chemical tongue Invited
Hiroka Sugai, Shunsuke Tomita, Ryoji Kurita
55 ( 5 ) 347 - 351 2023.3
-
Molecular array device and multivariate analysis for biological fluids Invited
Shunsuke Tomita, Hiroka Sugai, Tsukuru Minamiki, Ryoji Kurita
Denki Kagaku 88 ( 3 ) 262 - 271 2020.9
-
生体試料の特徴情報を出力する交差反応性ポリマーアレイを利用したバイオメトリクス Invited
菅井 祥加, 冨田 峻介, 栗田 僚二
ケミカルエンジニヤリング 63 ( 11 ) 842 - 849 2018.11
Awards
-
Editors' Choice Award 2025
2025.4 Biophysics and Physicobiology Chemical Tongues as Multipurpose Bioanalytical Tools for the Characterization of Complex Biological Samples
Shunsuke Tomita, Hiroka Sugai
-
Hot Article Award
2020.8 Analytical Sciences Pattern-recognition-based Sensor Arrays for Cell Characterization: From Materials and Data Analyses to Biomedical Applications
Hiroka Sugai, Shunsuke Tomita, Ryoji Kurita
Research Projects
-
バイオ高分子が織りなす異方形状メゾスケール構造体の創成
Grant number：25K18125 2025.4 - 2027.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grants-in-Aid for Early-Career Scientists
Hiroka Sugai
Authorship：Principal investigator
Grant amount：\4810000 （ Direct Cost: \3700000 、 Indirect Cost：\1110000 ）
-
Development of peptide tags for controlling the reversible assembly of proteins
2022.10 - 2026.3
Japan Science and Technology Agency Strategic Basic Research Programs PRESTO
Hiroka Sugai
Authorship：Principal investigator
-
短鎖ペプチドによるタンパク質不溶化の理解と精製技術への応用
Grant number：22K14777 2022.4 - 2025.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists
Hiroka Sugai
Authorship：Principal investigator
Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）
-
タンパク質液滴の特徴パターンを捉える蛍光色素修飾ペプチド群の開発
Grant number：21K20622 2021.8 - 2023.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up
Hiroka Sugai
Authorship：Principal investigator
Grant amount：\3120000 （ Direct Cost: \2400000 、 Indirect Cost：\720000 ）
-
グアニン四重鎖RNAに着目した相分離液滴の構造解析
2026.3 - 2027.4
上原記念生命科学財団 研究奨励金
菅井 祥加
Authorship：Principal investigator
-
グアニン四重鎖が織りなす液滴内ドメインの解明
2025.4 - 2026.3
Toyota Physical and Chemical Research Institute Toyota Riken Scholar
Hiroka Sugai
Authorship：Principal investigator
-
Structural Analysis of Quadruplex-Forming Oligonucleotides in a Biomolecular Condensate
2025.1 - 2025.12
Institute of Science Tokyo Yoshinori Ohsumi Award for Fundamental Research
Hiroka Sugai
Authorship：Principal investigator
-
Multi-step kinetic analysis of protein condensate aging using microfluidics
Grant number：24KK0104 2024.9 - 2028.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (International Collaborative Research)
Mao Fukuyama, Hiroka Sugai, Kichitaro Nakajima, Yoshiyuki Soeda
Authorship：Coinvestigator(s)
Grant amount：\20930000 （ Direct Cost: \16100000 、 Indirect Cost：\4830000 ）
-
Characterization of cultured cells based on pattern recognition using a set of fluorophores
2024.9 - 2025.8
Tokyo Institute of Technology Suematsu Award “Fundamentals and Developments of Innovative Value Creation"
Hiroka Sugai
Authorship：Principal investigator
-
バイオ高分子の階層的自己組織化に基づく細胞様構造体の創成
2024.4 - 2025.3
The Kao Foundation for Arts and Sciences Kao Crescent Award
Hiroka Sugai
Authorship：Principal investigator
-
Stratification of Protein Aggregation States based on Pattern Recognition for Screening Factors Controlling Phase Separation
Grant number：23H01995 2023.4 - 2026.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
Shunsuke Tomita, Eiichiro Mori, Tomohide Saio, Hiroka Sugai
Authorship：Coinvestigator(s)
Grant amount：\18980000 （ Direct Cost: \14600000 、 Indirect Cost：\4380000 ）
-
アミロイド形成を理解する相分離仮説の実証と共溶質の開発
Grant number：22K19284 2022.6 - 2024.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory)
Kentaro Shiraki, Hiroka Sugai
Authorship：Coinvestigator(s)
Grant amount：\6500000 （ Direct Cost: \5000000 、 Indirect Cost：\1500000 ）
-
タンパク質集合体制御タグに関する探索的研究
2021.10 - 2022.3
Japan Science and Technology Agency Strategic Basic Research Programs
Hiroka Sugai
Authorship：Principal investigator
-
大規模ポリマーライブラリを利用した細菌叢メトリクス
Grant number：20H02774 2020.4 - 2023.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
Shunsuke Tomita, Koyomi Miyazaki, Isao Yumoto, Hiroka Sugai
Authorship：Coinvestigator(s)
Grant amount：\18070000 （ Direct Cost: \13900000 、 Indirect Cost：\4170000 ）
-
安全性の高いがん細胞選択的核酸医薬システムの創成
Grant number：16J06422 2016.4 - 2018.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows
Hiroka Sugai