Updated on 2026/07/24

写真a

 
SAKAGUCHI TAKUYA
 
Organization
School of Engineering Professor for Institute Management
Title
Professor for Institute Management
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Papers

  • A Verification Study of a Computational Model for Simulating Transcatheter Edge-to-Edge Repair for Mitral Regurgitation Reviewed International coauthorship

    Fumimasa Shige, Junichi Ooida, Hironaga Noguchi, Koshiro Suzuki, Gakuto Aoyama, Takuya Sakaguchi

    Volume 4: Biomedical and Biotechnology   2025.11

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    Language：English   Publishing type：Research paper (international conference proceedings)   Publisher：American Society of Mechanical Engineers  

    Abstract

    In a previous study, we developed a one-way fluid-structure interaction (FSI) model to predict the effect of transcatheter edge-to-edge repair (TEER) on mitral regurgitation (MR). The FSI model consists of a valve deformation model (VDM) for valve dynamics and a lumped parameter model (LPM) for blood flow. For the clinical application of in silico models, it is necessary to verify their credibility to secure the safety. Many studies have been conducted on LPMs, few studies have discussed the patient dependence related to the discretization error. Therefore, as the first step in the credibility assessment, we perform a verification study considering the patient dependence on the error of the LPM. The VDM is compared with the analytical solutions by beam problems, and the LPM is verified using the data of 35 patients. The patient-specific LPMs are generated by parameter optimization with information obtained from medical images, and the behavior of discretization error is examined for MR. As a result, it is confirmed that the absolute value of the error and the dependence of the error on the time step are patient dependent. However, the patient dependence is small in both cases, and the behavior agrees qualitatively with that assumed from a numerical scheme. It is also found that the error of the regurgitation is suppressed to 0.1 ml or less when the time step is 5 μs or less.

    DOI： 10.1115/imece2025-163641

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  • Deep Learning-Based Fully Automated Aortic Valve Leaflets and Root Measurement From Computed Tomography Images ― A Feasibility Study ― Reviewed

    Haruo Yamauchi, Gakuto Aoyama, Hiroyuki Tsukihara, Kenji Ino, Naoki Tomii, Shu Takagi, Katsuhiko Fujimoto, Takuya Sakaguchi, Ichiro Sakuma, Minoru Ono

    Circulation Journal   2025.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1253/circj.cj-24-1031

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  • Development of myocardial perfusion imaging from coronary angiography for clinical application Reviewed

    Yuya Sekikawa, Yusuke Miyazaki, Takuya Sakaguchi

    Radiological Physics and Technology   2025.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s12194-025-00917-y

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  • Fully automatic fossa ovalis segmentation from computed tomography images using deep neural network with atlas-based localization Reviewed International coauthorship

    Gakuto Aoyama, Toru Tanaka, Yukiteru Masuda, Naoki Matsuki, Ryo Ishikawa, Masahiko Asami, Kiyohide Satoh, Takuya Sakaguchi

    Informatics in Medicine Unlocked   52   101613 - 101613   2025.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.imu.2025.101613

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Presentations

  • A verification study of a computational model for simulating transcatheter edge-to-edge repair for mitral regurgitation International conference

    2025.11 

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    Language：English   Presentation type：Oral presentation (general)  

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  • Evaluation of Myocardial Perfusion Images Generated from Coronary Angiography Compared to Nuclear Medicine Images International conference

    2025.11 

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    Language：English   Presentation type：Oral presentation (general)  

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  • そうだ、特許にしよう！ Invited

    坂口卓弥

    医療系産学連携ネットワーク協議会（medU-net）セミナー  2025.11 

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    Language：Japanese   Presentation type：Oral presentation (invited, special)  

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  • 最先端科学技術の学際的社会実装によるスマートヘルスケアの実現 Invited

    坂口卓弥

    分析機器・科学機器総合展セミナー  2025.9 

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    Language：Japanese   Presentation type：Oral presentation (invited, special)  

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  • Development of myocardial perfusion imaging from coronary angiography for clinical practice Invited International conference

    Yuya Sekikawa, Yusuke Miyazaki, Takuya Sakaguchi

    62nd International Scientific-Practical Conference  2025.4 

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    Language：English   Presentation type：Oral presentation (invited, special)  

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  • 冠動脈造影画像由来の心筋血流画像における最適な心位相の検討

    関川 祐矢, 宮崎勇輔, 坂口卓弥

    第81回日本放射線技術学会総会学術大会  2025.4 

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    Language：Japanese   Presentation type：Oral presentation (general)  

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Awards

  • 1st Place Award

    2025.4   Kyrgyz State Medical Academy   Development of myocardial perfusion imaging from coronary angiography for clinical practice

    Yuya Sekikawa, Yusuke Miyazaki, Takuya Sakaguchi

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    Award type：Award from international society, conference, symposium, etc.  Country：Kyrgyzstan

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