Organization
School of Computing Assistant Professor
Title
Assistant Professor
Homepage
External link
HAMADA SHOGO
Degree
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Dr. Eng. ( 2011.3 Tokyo Institute of Technology )
Research Interests
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分子ロボティクス
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Biorobotics
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DNA Nanoengineering
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DNA Nanotechnology
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DNAナノエンジニアリング
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DNAナノテクノロジー
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DNAハイドロゲル
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Molecular Robotics
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Nanorobotics
Research Areas
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Informatics / Intelligent robotics
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Informatics / Life, health and medical informatics
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Nanotechnology/Materials / Nanobioscience
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Nanotechnology/Materials / Polymer materials
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Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Control and system engineering
Research History
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Biomolecular Design Institute, Chem-Bio Informatics Society Director
2024.8
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Tokyo Institute of Technology School of Computing Assistant Professor (Tenure-track, PI)
2024.4
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Tokyo Institute of Technology School of Computing Assistant Professor
2023.7 - 2024.3
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Tohoku University Graduate School of Engineering Department of Robotics Specially Appointed Lecturer
2021.1 - 2023.6
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Cornell University Dept. of Biological and Environmental Engineering Lecturer
2018.1 - 2020.12
Country：United States
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Cornell University Dept. of Biological and Environmental Engineering Research Associate
2016.5 - 2020.12
Country：United States
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Cornell University Kavli Institute at Cornell for Nanoscale Science Kavli Postdoctoral Fellow
2013.4 - 2016.4
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Tohoku University Graduate School of Engineering, Department of Bioengineering and Robotics, Robotics,Molecular Robotics Assistant Professor
2011.4 - 2013.3
Committee Memberships
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文部科学省 科学技術・学術政策研究所 科学技術専門家ネットワーク・専門調査員
2025.6 - 2026.3
Committee type：Government
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Molecular Robotics Society Delegate
2025.4 - 2027.3
Committee type：Academic society
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Biomolecular Design Institute, CBI Research Institute Chair
2024.8
Committee type：Academic society
Papers
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Slime-type Molecular Robots and Their Applications
Shogo Hamada
The Journal of IEICE 108 ( 11 ) 1078 - 1085 2025.11
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Quasi-Phototaxis in Slime-Type Molecular Robots Reviewed
Shogo Hamada, Sota Kumagai, Shin-ichiro M. Nomura, Satoshi Murata
2025 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS) 1 - 6 2025.7
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Farhana Afroze, Richard Archer, Mahammad Mustakim, Rakesh Das, Arif Md. Rashedul Kabir, Yuuto Miura, Rubaya Rashid, Tetsuya Hiraiwa, Shin-ichiro M. Nomura, Shogo Hamada, Akira Kakugo
ChemRxiv 2025.6
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生体分子デザイン研究所が目指す多角的分野支援 Invited
浜田省吾
CBI学会誌 13 ( 2 ) 7 - 9 2025.6
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スライム型分子ロボット Reviewed
浜田 省吾, 平塚 祐一
ファルマシア 61 ( 4 ) 314 - 318 2025.4
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Micrometer‐Sized Liposome‐Based Systems: A Hierarchical Breakdown Reviewed
Shogo Hamada, Hironori Sugiyama, Yiting Zhang, Shoji Iwabuchi, Soichiro Hiroi, Toshiki Maruyama, Yuktesh Balaji, Sota Kumagai, Satoshi Murata, Taro Toyota
ChemSystemsChem 2025.1
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[Preprint] Transmembrane DNA Sequence Signaling via Hybridization
Kai Yoshida, Keita Abe, Yusuke Sato, Ibuki Kawamata, Richard James Archer, Hideaki T. Matsubayashi, Shogo Hamada, Satoshi Murata, Shin-ichiro Nomura
ChemRxiv 2024.7
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Development of DNA Gel Robots with “Artificial” Metabolism Reviewed
Shogo HAMADA
Seibutsu Butsuri 64 ( 1 ) 17 - 20 2024
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Scalable Synthesis of Planar Macroscopic Lipid-Based Multi-Compartment Structures. Reviewed International journal
Richard J Archer, Shogo Hamada, Ryo Shimizu, Shin-Ichiro M Nomura
Langmuir : the ACS journal of surfaces and colloids 2023.3
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Interfacing DNA hydrogels with ceramics for biofunctional architectural materials Reviewed
Yehudah A. Pardo, Kenneth G. Yancey, David S. Rosenwasser, David M. Bassen, Jonathan T. Butcher, Jenny E. Sabin, Minglin Ma, Shogo Hamada, Dan Luo
Materials Today 53 98 - 105 2022.3
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Molecular Robotics Reviewed
Shogo Hamada
Encyclopedia of Robotics 1 - 17 2021.2
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DNA-based engineering system for improving human and environmental health: Identification, detection, and treatment Reviewed
Renkuan Liao, Feng Zhao, Shogo Hamada, Peiling Yang, Huan Xu, Dan Luo, Dayong Yang
NANO TODAY 35 2020.12
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Enzyme-based fabrication of physical DNA hydrogels: new materials and applications Reviewed
Shogo Hamada, Dan Luo
POLYMER JOURNAL 52 ( 8 ) 891 - 898 2020.8
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Transformation of Biomass DNA into Biodegradable Materials from Gels to Plastics for Reducing Petrochemical Consumption Reviewed International journal
Dong Wang, Jinhui Cui, Mingzhe Gan, Zhaohui Xue, Jing Wang, Peifeng Liu, Yue Hu, Yehudah Pardo, Shogo Hamada, Dayong Yang, Dan Luo
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 142 ( 22 ) 10114 - 10124 2020.6
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Three-dimensional nanoparticle assemblies with tunable plasmonics via a layer-by-layer process Reviewed
Thomas L. Derrien, Shogo Hamada, Max Zhou, Detlef-M Smilgies, Dan Luo
NANO TODAY 30 2020.2
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Dynamic DNA material with emergent locomotion behavior powered by artificial metabolism Reviewed International journal
Shogo Hamada, Kenneth Gene Yancey, Yehudah Pardo, Mingzhe Gan, Max Vanatta, Duo An, Yue Hu, Thomas L. Derrien, Roanna Ruiz, Peifeng Liu, Jenny Sabin, Dan Luo
SCIENCE ROBOTICS 4 ( 29 ) 2019.4
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Reversible Gel-Sol Transition of a Photo-Responsive DNA Gel Reviewed International journal
Daisuke Kandatsu, Keitel Cervantes-Salguero, Ibuki Kawamata, Shogo Hamada, Shin-ichiro M. Nomura, Kenzo Fujimoto, Satoshi Murata
CHEMBIOCHEM 17 ( 12 ) 1118 - 1121 2016.6
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Self-replication of DNA rings Reviewed International journal
Junghoon Kim, Junwye Lee, Shogo Hamada, Satoshi Murata, Sung Ha Park
NATURE NANOTECHNOLOGY 10 ( 6 ) 528 - U102 2015.6
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Polymorphic Ring-Shaped Molecular Clusters Made of Shape-Variable Building Blocks Reviewed International journal
Keitel Cervantes-Salguero, Shogo Hamada, Shin-ichiro M. Nomura, Satoshi Murata
NANOMATERIALS 5 ( 1 ) 208 - 217 2015.3
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DNA Materials: Bridging Nanotechnology and Biotechnology Reviewed International journal
Dayong Yang, Mark R. Hartman, Thomas L. Derrien, Shogo Hamada, Duo An, Kenneth G. Yancey, Ru Cheng, Minglin Ma, Dan Luo
ACCOUNTS OF CHEMICAL RESEARCH 47 ( 6 ) 1902 - 1911 2014.6
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NANOPARTICLE CRYSTALLIZATION DNA-bonded 'atoms' Reviewed International journal
Shogo Hamada, Shawn J. Tan, Dan Luo
NATURE MATERIALS 13 ( 2 ) 121 - 122 2014.2
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Quantitative analysis of molecular-level DNA crystal growth on a 2D surface Reviewed International journal
Junwye Lee, Shogo Hamada, Si Un Hwang, Rashid Amin, Junyoung Son, Sreekantha Reddy Dugasani, Satoshi Murata, Sung Ha Park
SCIENTIFIC REPORTS 3 2115 - 2115 2013.7
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Point-of-care nucleic acid detection using nanotechnology Reviewed International journal
Mark R. Hartman, Roanna C. H. Ruiz, Shogo Hamada, Chuanying Xu, Kenneth G. Yancey, Yan Yu, Wei Han, Dan Luo
NANOSCALE 5 ( 21 ) 10141 - 10154 2013
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Cervantes Keitel, Hamada Shogo, Nomura Shin-ichiro, Murata Satoshi
Seibutsu Butsuri 53 ( 1 ) S211 2013
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3P124 Design and construction of a DNA microcapsule toward lightresponsive molecular robots(05A. Nucleic acid: Structure & Property,Poster)
Tsuganezawa Yuichi, Morita Masamune, Hamada Shogo, Nomura Shin-ichiro M., Fujimoto Kenzo, Murata Satoshi, Takinoue Masahiro
Seibutsu Butsuri 53 ( 1 ) S232 2013
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Size-Controllable DNA Rings with Copper-Ion Modification Reviewed International journal
Junwye Lee, Shogo Hamada, Rashid Amin, Sunho Kim, Atul Kulkarni, Taesung Kim, Yonghan Roh, Satoshi Murata, Sung Ha Park
SMALL 8 ( 3 ) 374 - 377 2012.2
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3PT112 Adsorption of DNA ring onto Liposome(The 50th Annual Meeting of the Biophysical Society of Japan)
Kumagai Yumiko, Hamada Shogo, Nomura Shin-ichiro, Murata Satoshi
Seibutsu Butsuri 52 S159 2012
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3PT113 Substrate-Assisted Self-Assembly of DNA Nanostructure on lipid bilayer(The 50th Annual Meeting of the Biophysical Society of Japan)
Kudo Shogo, Hamada Shogo, Nomura Shin-ichiro, Murata Satoshi
Seibutsu Butsuri 52 S159 2012
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3PT109 Model for self-assembly of flexible DNA motifs using stacking interactions(The 50th Annual Meeting of the Biophysical Society of Japan)
Cervantes-Salguero Keitel, Hamada Shogo, Murata Satoshi
Seibutsu Butsuri 52 S159 2012
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Theoretical model of substrate-assisted self-assembly of DNA nanostructures Reviewed
Shogo Hamada, Satoshi Murata
RSC ADVANCES 2 ( 19 ) 7406 - 7412 2012
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1PT227 Prototype molecular robots working on cellular membrane(The 50th Annual Meeting of the Biophysical Society of Japan)
Sato Yusuke, Fujiwara Kei, Hamada Shogo, Murata Satoshi, Nomura Sin-ichiro
Seibutsu Butsuri 52 S107 2012
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A Crystal Growth Approach for DNA Nano-Structure Formation Reviewed
Hitoshi Miura, Yuya Ueno, Shogo Hamada, Satoshi Murata, Katsuo Tsukamoto
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 67 C537 - C537 2011
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Algorithmic Self-assembly of Single-duplex DNA Nanostructures Reviewed
Shogo Hamada, Satoshi Murata
INTERNATIONAL JOURNAL OF UNCONVENTIONAL COMPUTING 7 ( 1-2 ) 25 - 37 2011
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Construction of a genetic AND gate under a new standard for assembly of genetic parts Reviewed International journal
Shotaro Ayukawa, Akio Kobayashi, Yusaku Nakashima, Hidemasa Takagi, Shogo Hamada, Masahiko Uchiyama, Katsuyuki Yugi, Satoshi Murata, Yasubumi Sakakibara, Masami Hagiya, Masayuki Yamamura, Daisuke Kiga
BMC GENOMICS 11 S16 2010.12
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DNA Tiles Reviewed
Murata, S, Hamada, S
Journal of the Robotics Society of Japan 28 ( 10 ) 1158 - 1161 2010
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Extending the Geometrical Design of DNA Nanostructures Reviewed
Shogo Hamada, Satoshi Murata
NATURAL COMPUTING 2 157 - 164 2010
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Substrate-Assisted Assembly of Interconnected Single-Duplex DNA Nanostructures Reviewed International journal
Shogo Hamada, Satoshi Murata
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 48 ( 37 ) 6820 - 6823 2009
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SYANAC: SYnthetic biological Automaton for Noughts and Crosses Reviewed
S. Ayukawa, A. Kobayashi, Y. Nakashima, H. Takagi, S. Hamada, M. Uchiyama, K. Yugi, S. Murata, Y. Sakakibara, M. Hagiya, M. Yamamura, D. Kiga
IET Synthetic Biology 1 ( 1-2 ) 64 - 67 2007
Books
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分子ロボティクス概論 : 分子のデザインでシステムをつくる
分子ロボティクス研究会, 村田, 智（ Role： Contributor）
CBI学会 2019 （ ISBN:9784990907648 ）
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現代化学 2016年8月号「さまざまなDNAナノ構造」
（ Role： Contributor）
東京化学同人 2016.8
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DNA分子デザインのすべて : BIOMOD虎の巻
分子ロボティクス研究会（ Role： Contributor）
情報計算化学生物学会 2016 （ ISBN:9784990907679 ）
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Opinions and Outlooks on Morphological Computation
（ Role： Contributor）
2014
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DNAナノエンジニアリング
近代科学社 2011 （ ISBN:9784764904026 ）
MISC
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Molecular Robotics (web article)
Shogo Hamada
Springer (Robotics and Automation Campaign) https://www.springer.com/gp/campaign/robotics-automation/shogo-hamada 2021.10
Presentations
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Development of Functional DNA Nanofibers towards Cell Culture Applications
Mihane KAWADA, Katsunori AIZAWA, Kureha SUZUKI, Hiromi NAKATA, Ryusei MATSUMOTO, Kazumasa OHTAKE, Taku MATSUSHITA, Seiichi ISHIDA, Daisuke KIGA, Tomoaki MATSUURA, Akihiko KONAGAYA, Shin-ichiro M. NOMURA, Shogo HAMADA
CBI Annual Meeting 2025 2025.10
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CBI研究機構 生体分子デザイン研究所のご紹介
浜田 省吾
CBI学会2025年大会 CBI研究機構シンポジウム2025 2025.10
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基礎と応用の両輪で進む： スライム型分子ロボットを例として Invited
浜田 省吾
第8回分子ロボティクス年次大会 2025.3
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Development and Applications of Functional DNA Hydrogels Invited
Shogo Hamada
12th Singapore International Chemistry Conference 2024.12
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Mesoscale DNA-based Machines Powered by Artificial Metabolism Invited
Shogo Hamada
The 59th Annual Meeting of the Biophysical Society of Japan 2021.11
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Development of slime-like, DNA-based machines powered by artificial metabolism Invited
Shogo Hamada
Cell Synth14.0 meeting 2021.11
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Towards "life-like"molecular robotics Invited
Shogo Hamada
ACSE Research Seminar 2021.11
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DNAハイドロゲルとその応用：分子ロボットから診断，機能性材料へ Invited
浜田 省吾
第３回 エルゴチオネイン・セレノネイン研究会 2022.12
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「スライム型分子ロボット」 プロトタイプから材料・診断応用へ Invited
浜田 省吾
第7回分子ロボット倫理研究会医療系研究開発WG 2022.11
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ここまできた！分子ロボット - 最新応用事例のご紹介 Invited
浜田 省吾
分子ロボットと循環農工業：持続可能な未来を目指して（CBI学会市民講座） 2022.10
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DNAゲル分子ロボットの今と循環共生圏農工業への貢献可能性 Invited
浜田 省吾
循環共生圏研究推進体オンラインワークショップ 2022.7
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スライム型分子ロボットとその医療応用への展望 Invited
浜田省吾
CBI学会2024年大会: 分子ロボット倫理シンポジウム「分子ロボット創薬への期待と現実とのギャップの解消に向けて」 2024.10
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Development and applications of slime-type molecular robots with artificial metabolism Invited
Shogo Hamada
Synthetic Biology based on Informatics and Experimental approaches 2024.9
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生体模倣システム創製へ向けた分子ロボティクスの応用 Invited
浜田省吾
QST生体模倣システム創製研究アライアンス会議勉強会 2024.3
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代謝するDNAハイドロゲルによるインテリジェント人工細胞外マトリックスの開発 Invited
浜田省吾
新化学技術推進協会 第12回研究奨励賞受賞講演 2023.8
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Extending the geometrical design of DNA nanostructures
Fourth International Workshop on Natural Computing (IWNC09). 2009.9
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Macroscale DNA Structures toward Molecular Robotics. Invited
The 3rd Molecular Robotics Workshop 2014.3
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Substrate-Assisted Self-Assembly of DNA Nanostructures. Invited
1st DNA Nanotechnology Forum. 2012.12
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A Preliminary Study on Colloidal Crystallization of DNA Motifs. Invited
9th Annual Conference Foundations of Nanoscience (FNANO12). 2012.4
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Theoretical Model of Substrate-Assisted Self-Assembly of DNA Motif.
17th International Conference on DNA Computing and Molecular Programming. 2011.9
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Dawn of “life-like” molecular robotics Invited
Springer Nature Applied Sciences Webinar 2021.5
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Dynamic DNA-based machines powered by artificial metabolism. Invited
International Conference on Manipulation, Automation and Robotics at Small Scales. 2019.7
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Creating a self-regeneratable material by DNA.
5th Nano Today Conference. 2017.12
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DNA Hydrogel: towards realization of “slime-like” molecular robots. Invited
Tokyo Tech Symposium "Towards the Next Stages of Robotics". 2015.1
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「生きたロボット」の創りかた？！〜分子ロボティクスへの誘い〜 Invited
浜田省吾
東京科学大学 工大祭 公開講義 2024.11
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Quasi-Phototaxis in Slime-Type Molecular Robots
Shogo Hamada
International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS) 2025.7
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DNAは未来の材料？！医療応用から分子ロボットまで，生体分子デザインが切り開く未来 Invited
浜田省吾
国際科学技術財団 2025.8
Industrial property rights
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機能性構造体およびその製造方法
佐藤佑介, 富永大智, 浜田省吾
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核酸構造体及びその核酸構造体を用いた核酸構造物
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SYSTEM AND METHODS FOR GENERATING DYNAMIC MATERIALS HAVING ARTIFICIAL METABOLISM
Works
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Polybrick (Mutations / Créations, Centre Pompidou, Paris, France)
Jenny Sabin, Dan Luo, Shogo Hamada
2017.3 - 2017.6
Research Projects
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Development of Smart Pesticides Using Aerial Molecular Robots
2025.4 - 2026.3
Heisei Memorial Research Grant Program
Authorship：Principal investigator
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Synthesis of hybrid multicomponent materials using DNA microgel platform
Grant number：24H01122 2024.4 - 2026.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A)
Authorship：Principal investigator
Grant amount：\9620000 （ Direct Cost: \7400000 、 Indirect Cost：\2220000 ）
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Exploration of Programmable Materials Engineering through the Development of Hybrid DNA Fibers
Grant number：JPMJPR23Q7 2023.10 - 2027.3
Japan Science and Technology Agency JST PRESTO
Shogo Hamada
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DNAと微小管による動的ネットワーク材料システムの構築
2023.7
双葉電子記念財団 自然科学研究助成
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代謝するDNAハイドロゲルによるインテリジェント人工細胞外マトリックスの開発
2023.7
新化学技術推進協会 第12回新化学技術研究奨励賞
Authorship：Principal investigator
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Development of evolvable hybrid material discovery system
Grant number：22H05396 2022.6 - 2024.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A) Grant-in-Aid for Transformative Research Areas (A)
Authorship：Principal investigator
Grant amount：\9880000 （ Direct Cost: \7600000 、 Indirect Cost：\2280000 ）
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Development of Reactive Molecular Robotics Powered by Artificial Metabolism
Grant number：22K12239 2022.4 - 2027.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Grant amount：\3900000 （ Direct Cost: \3000000 、 Indirect Cost：\900000 ）
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DNA オリガミと人工代謝系の融合によるマルチプレックス核酸検出機構の開発
2022.4 - 2023.3
理化学研究所・東北大学 理研-東北大科学技術ハブ共同研究プログラム
Authorship：Principal investigator
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核酸検出装置の開発
2021.11
株式会社ダッシュマテリアルズ 共同研究・寄付金
Authorship：Principal investigator
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Construction of Minimal Artificial Brain by Molecular Device Integration and its Social Innovation
Grant number：20H05969 2020.11 - 2025.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A)
Authorship：Coinvestigator(s)
Grant amount：\168350000 （ Direct Cost: \129500000 、 Indirect Cost：\38850000 ）
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Motion generation based on cooperation of structured gel and chemical reaction field
Grant number：24104005 2012.6 - 2017.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area) Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Hagiya Masami, KAWAMATA Ibuki, HAMADA Shogo
Grant amount：\303810000 （ Direct Cost: \233700000 、 Indirect Cost：\70110000 ）
In the study of slime type robot, we aimed "expansion of scale" of molecular robot. Specifically, using a polymer gel as a reaction field, a heterogeneous reaction space of order of millimeter is generated, and various molecular devices are operated on it. This concept ultimately aims at realization of macroscopic functions such as taxis. The results obtained in the project include a method of controlling reaction/diffusion behavior of molecular devices based on quantitative measurement in a gel, development of various new gel actuators, a method of controlling sol-gel phase transition, and a theoretical framework called “gel automaton” for programming the discrete reaction fields defined on the cell space of the gel.
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Design and Fabrication of Dynamic DNA Nanostructures for MolecularRobotics
Grant number：23800006 2011 - 2012
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up Grant-in-Aid for Research Activity Start-up
HAMADA Shogo
Grant amount：\3250000 （ Direct Cost: \2500000 、 Indirect Cost：\750000 ）
Several types of flexible DNA nanostructures were designed and fabricated. The structures were designed to be compatible with state transition using strand displacement techniques. DNA nanostructures that represents the ideal formation of each state were observed, in order to evaluate the effectiveness of this design methodology.
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Development of molecular robotics based on DNA nanoengineering
Grant number：22220001 2010.4 - 2015.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S) Grant-in-Aid for Scientific Research (S)
MURATA Satoshi, KUZUYA Akinori, TAKINOUE Masahiro, SEKIYAMA Kosuke, NOMURA Shin-ichiro, FUJIMOTO Kenzo, TAKEUCHI Shyoji, KOBAYASHI Satoshi, KAWAMATA Ibuki, MORITA Masamune, HAMADA Shogo
Grant amount：\214110000 （ Direct Cost: \164700000 、 Indirect Cost：\49410000 ）
In this research project, aiming at developing fundamental techniques to construct molecular robots composed of molecular devices rigorously designed from scratch, which are able to adapt to various environmental changes. The developed technologies based on DNA nano-engineering include
(1) Techniques to fabricate compartments which compose the body of molecular robot containing molecular devices, (2) Techniques to realize interface, which realizes molecular communication across the compartment, (3) Techniques to control the molecular computation in molecular robots and intra-and inter-molecular robot communication, (4) Techniques to design cooperative behaviors of swarm of multiple molecular robots. -
新規核酸基本構造単位を用いたナノ構造体作製及びそのデバイス応用
Grant number：09J08655 2009 - 2010
日本学術振興会 科学研究費助成事業 特別研究員奨励費 特別研究員奨励費
浜田 省吾
Grant amount：\2100000 （ Direct Cost: \2100000 ）
昨年度(T-motifを利用した大規模構造作製技術の考案,複数種類の構造作製,アルゴリズミック・セルフアセンブリへの拡張)に引き続き,本年度はT-motifを利用した複合ナノデバイス作製のための技術を開発した.具体的には,「基板上成長法」により大規模成長するT-motifアレイとDNAオリガミと呼ばれるアドレッシング可能な100nm四方程度の構造を組み合わせた,大規模ナノ構造の作製をおこなった.これにより,将来的には,複数の機能性粒子が必要な小規模な反応系についてはDNAオリガミ上で,一方で大規模な反応系についてはT-motif上でおこなうことができる.本技術は,それぞれを組み合わせた複合的なデバイスを作製するための基礎となる.
また,これと並行して,基板上成長の自己集合と吸着を説明する理論の構築,およびこの理論を利用した例として,T-motif構造の構造形成に関する速度論シミュレーションをおこなった,理論は三段階からなる.第一段階は「自己集合」と「吸着」の現象に関し,前者はDNAのハイブリダイゼーションについてNearest-Neighbor法を用いることで,後者は基板-DNA間の相互作用についてDLVO理論を用いることで,それぞれの自由エネルギー変化を算出した.第二段階として,算出した自由エネルギー変化を熱力学平衡の式に導入し,それぞれの状態間の関係を明らかにした.第三段階として,第二段階で求めた平衡式から準静的状態における速度式を導出し,状態間の速度を算出した.これにより,それぞれの状態における時間的発展を任意の基板,イオン濃度や温度などで表現することができる.ここではその具体例としてリング構造の基板上成長シミュレーションを行ない,実験結果との定性的な一致をみたことで,理論の妥当性を確認した.この理論とシミュレーションは,今後さまざまな条件での基板上成長法の設計に重要な知見を与えるものである.
Teaching Experience
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Non-linear Dynamical Systems
2025 Institution：Institute of Science Tokyo
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Control Systems
2024 Institution：Institute of Science Tokyo
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Design Theory in Biological Systems
2024 Institution：Institute of Science Tokyo
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Fundamentals of System Science
2024 Institution：Institute of Science Tokyo
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Foundation of Molecular Robotics
2021.4 - 2023 Institution：Tohoku University
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Individual Study in Biological and Environmental Engineering (BEE 4970)
2019 - 2020 Institution：Cornell University
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Biorobotics (BEE 4570)
2018.1 - 2020.12 Institution：Cornell University
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Experiments for Mechanics and Aerodynamics I
2012 - 2013 Institution：Tohoku University
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Experiments for Mechanics and Aerodynamics II
2011 - 2013 Institution：Tohoku University
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An Introduction to Molecular Engineering
2011 - 2012 Institution：Tohoku University
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Introduction to Molecular Robotics
2011 Institution：Tohoku University