Updated on 2026/04/12

写真a

 
HATA YUUKI
 
Organization
School of Materials and Chemical Technology Assistant Professor
Title
Assistant Professor
Contact information
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東京科学大学 芹澤・澤田研究室　　　Google Scholar　　　ResearchGate

多糖集合体による微生物制御に関する研究を行っています。

 

＜総説論文＞

  • 人工ナノセルロースについて：Y. Hata* and T. Serizawa*, Nanoarchitectonics of cello-oligosaccharides: A route toward artificial nanocelluloses. Adv. Colloid Interface Sci. 2025, 336, 103361.
  • Account：Y. Hata*, Self-assembly of low-molecular-weight cellulose into nanostructured macroscopic materials. Polym. J. 2026, 58, 31. (Front cover)

 

＜原著論文＞

  • ナノスパイク化ガーゼの作製と熱傷創からの細菌吸着除去：Y. Hata* et al., "Nanospiked cellulose gauze that attracts bacteria with biomolecules for reducing bacterial load in burn wounds". Nano Lett. 2025, 25, 1177.
  • ナノスパイク化ペーパーの作製と銀ナノ粒子合成：Y. Hata* et al., Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly. Carbohydr. Polym. 2023, 300, 120257.
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Degree

  • Doctor of Engineering ( 2019.3   Tokyo Institute of Technology )

Research Interests

  • Infection Control

  • Crystal

  • Self-Assembly

  • Polysaccharide

  • Cellulose

  • Microorganism Control

Research Areas

  • Nanotechnology/Materials / Nanomaterials

  • Nanotechnology/Materials / Polymer materials

  • Life Science / Hygiene and public health (laboratory)

  • Nanotechnology/Materials / Bio chemistry

Education

  • Tokyo Institute of Technology   School of Materials and Chemical Technology   Department of Chemical Science and Engineering

    2016.4 - 2019.3

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    Country： Japan

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  • Tokyo Institute of Technology   Graduate School of Science and Engineering   Department of Organic and Polymeric Materials

    2014.4 - 2016.3

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    Country： Japan

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  • Tokyo Institute of Technology   School of Engineering   Department of Polymer Chemistry

    2010.4 - 2014.3

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    Country： Japan

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Research History

  • Institute of Science Tokyo   School of Materials and Chemical Technology   Assistant Professor

    2024.10

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    Country：Japan

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  • National Defense Medical College   National Defense Medical College Research Institute

    2023.4

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    Country：Japan

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  • Tokyo Institute of Technology   School of Materials and Chemical Technology   Assistant Professor

    2023.4 - 2024.9

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    Country：Japan

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  • National College of Nursing, Japan

    2022.4

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    Country：Japan

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  • National Defense Medical College   Research Institute   Assistant Professor

    2020.8 - 2023.3

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    Country：Japan

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  • The University of Tokyo   The Graduate School of Engineering

    2020.4 - 2020.7

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    Country：Japan

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  • Tokyo Institute of Technology   School of Materials and Chemical Technology

    2019.4 - 2020.3

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    Country：Japan

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  • Tokyo Institute of Technology   School of Materials and Chemical Technology

    2018.4 - 2019.3

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    Country：Japan

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Professional Memberships

  • MRS-J

    2025.7

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  • Research Group on Biomedical Polymers, SPSJ

    2024.3

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  • National Defense Medical Society

    2021.5 - 2023.3

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  • The Society for Antibacterial and Antifungal Agents

    2021.4

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  • Japanese Society for Infection Prevention and Control

    2021.2 - 2023.4

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  • Forum on Biopolymers Science, SPSJ

    2018.4

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  • The Society of Polymer Science, Japan

    2015.1

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  • The Chemical Society of Japan

    2013.12

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Committee Memberships

  • The Society of Polymer Science, Japan, Tokyo Young Polymer Scientists   代表  

    2026.1 - 2026.12   

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    Committee type：Academic society

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  • Materials Research Society of Japan   Session Organizer  

    2025.4   

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    Committee type：Academic society

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  • The Society of Polymer Science, Japan, Tokyo Young Polymer Scientists   世話人  

    2020.5   

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    Committee type：Academic society

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Papers

  • Propargylated cello-oligosaccharide nanosheets: a water-dispersible, antibiofouling, and post-functionalizable solid support for immunoassays Reviewed International journal

    Kai Sugiura, Yuuki Hata, Koichiro Ishibashi, Toshiki Sawada, Hiroshi Tanaka, Go Watanabe, Takeshi Serizawa

    Journal of Materials Chemistry B   14 ( 2 )   528 - 538   2026.1

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Royal Society of Chemistry (RSC)  

    Propargylated cello-oligosaccharide nanosheets exhibited significant potential as a solid support for conjugation of oligo(ethylene glycol) (OEG) chains and enzyme-linked immunosorbent assay of anti-poly(ethylene glycol) (PEG) antibodies.

    DOI： 10.1039/d5tb01372k

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  • pH-Triggered Coassembly of Cello-oligosaccharides and Hyaluronic Acid into Hydrogels Reviewed International journal

    Takako Ida, Yuuki Hata, Thomas Sakata, Yuta Yamamoto, Takuya Katashima, Toshiki Sawada, Takeshi Serizawa

    ACS Applied Bio Materials   9 ( 1 )   423 - 432   2026.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

    DOI： 10.1021/acsabm.5c02001

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  • Self-assembly of low-molecular-weight cellulose into nanostructured macroscopic materials Invited Reviewed International journal

    Yuuki Hata

    Polymer Journal   58 ( 1 )   31 - 41   2026.1

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    Authorship：Lead author,　Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Nanocelluloses, which are prepared from natural cellulose sources in a top-down manner through physical and/or chemical treatments, are broadening the scope of applications of sustainable biopolymers. These naturally derived nanocelluloses exhibit one-dimensional nanomorphologies, such as nanofibers and nanorods, which originate from the intrinsic nanostructures formed by cellulose molecules in plants and other cellulose-producing organisms. Recent studies have developed artificial nanocelluloses that are constructed in vitro at the molecular level via the self-assembly of low-molecular-weight (LMW) cellulose. These artificial nanocelluloses feature unique nanostructures, including rectangular nanosheets, square nanosheets, distorted nanosheets, and helical nanorods. Nevertheless, most artificial nanocelluloses reported to date are particulates. We have developed two types of nanostructured macroscopic materials through the self-assembly of LMW cellulose: nanoribbon network hydrogels and nanospiked microfibrous materials. These novel nanostructured cellulose materials have shown great promise for distinctive applications of cellulose. This Focus Review summarizes our work along with related studies on nanostructured macroscopic materials constructed via the self-assembly of LMW cellulose.

    DOI： 10.1038/s41428-025-01101-0

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    Other Link： https://www.nature.com/articles/s41428-025-01101-0

  • Electrostatic control of protein adsorption onto negatively charged crystalline cello-oligosaccharide assemblies Reviewed International journal

    Kai Sugiura, Akari Matsunami, Yuuki Hata, Hiroshi Tanaka, Takeshi Serizawa

    Polymer Journal   2025.9

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1038/s41428-025-01104-x

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    Other Link： https://www.nature.com/articles/s41428-025-01104-x

  • Plant cell wall-inspired synthesis of biomolecular self-assembled stiff hydrogels Reviewed

    Yuta Sakurai, Yuuki Hata, Mahiro Tashiro, Riho Fujikura, Takuya Katashima, Hironori Marubayashi, Toshiki Sawada, Takeshi Serizawa

    Communications Materials   6 ( 1 )   150   2025.7

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1038/s43246-025-00874-4

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    Other Link： https://www.nature.com/articles/s43246-025-00874-4

  • Synthesis of Water-Soluble Cyano-Containing Polymeric Additives and Their Application to the Preparation of Ag+-Loaded Hydrogels Reviewed

    Xu Chen, Yuuki Hata, Hidetoshi Matsumoto, Takeshi Serizawa, Tsuyoshi Michinobu

    ACS Applied Polymer Materials   7 ( 12 )   8245 - 8253   2025.6

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acsapm.5c01383

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  • Nanoarchitectonics of cello-oligosaccharides: A route toward artificial nanocelluloses Invited Reviewed

    Yuuki Hata, Takeshi Serizawa

    Advances in Colloid and Interface Science   336   103361 - 103361   2025.2

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.cis.2024.103361

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  • Nanospiked Cellulose Gauze That Attracts Bacteria with Biomolecules for Reducing Bacterial Load in Burn Wounds Reviewed International journal

    Yuuki Hata, Hiromi Miyazaki, Sayaka Okamoto, Takeshi Serizawa, Shingo Nakamura

    Nano Letters   25 ( 3 )   1177 - 1184   2025.1

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acs.nanolett.4c05773

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  • Modulating neutralization-induced self-assembly of cello-oligosaccharides by organic solvents and temperature for preparing gels with improved mechanical properties Reviewed

    Mahiro Tashiro, Yuuki Hata, Toshiki Sawada, Hironori Marubayashi, Izuru Kawamura, Takeshi Serizawa

    Cellulose   31   9057 - 9073   2024.8

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s10570-024-06068-4

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    Other Link： https://link.springer.com/article/10.1007/s10570-024-06068-4/fulltext.html

  • Freeze-Dryable, StableFreeze-Dryable, Stable, and Click-Reactive Nanoparticles Composed of Cello-oligosaccharides for Biomolecular Sensing Reviewed

    Fumi Suehiro, Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    ACS Applied Bio Materials   7 ( 6 )   4007 - 4016   2024.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acsabm.4c00359

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  • Sequential Approach for Water Purification Using Seashell-Derived Calcium Oxide through Disinfection and Flocculation with Polyphosphate for Chemical Pollutant Removal Reviewed

    Yuuki Hata, Sumiyo Hiruma, Hiromi Miyazaki, Shingo Nakamura

    ACS Omega   9 ( 11 )   12635 - 12642   2024.3

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acsomega.3c07627

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  • Surface-mediated self-assembly of click-reactive cello-oligosaccharides for fabricating functional nonwoven fabrics Invited Reviewed

    Yudai Mizuuchi, Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Science and Technology of Advanced Materials   25 ( 1 )   2311052   2024.2

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Informa UK Limited  

    DOI： 10.1080/14686996.2024.2311052

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  • Interfacial jamming of surface-alkylated synthetic nanocelluloses for structuring liquids Reviewed

    Hirotaka Kamada, Yuuki Hata, Kai Sugiura, Toshiki Sawada, Takeshi Serizawa

    Carbohydrate Polymers   331   121896 - 121896   2024.2

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.carbpol.2024.121896

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  • Antibacterial Synthetic Nanocelluloses Synergizing with a Metal-Chelating Agent Reviewed

    Takeshi Serizawa, Saeko Yamaguchi, Kai Sugiura, Ramona Marten, Akihisa Yamamoto, Yuuki Hata, Toshiki Sawada, Hiroshi Tanaka, Motomu Tanaka

    ACS Applied Bio Materials   7 ( 1 )   246 - 255   2024.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

    DOI： 10.1021/acsabm.3c00846

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  • Distinguishing anti-PEG antibodies by specificity for the PEG terminus using nanoarchitectonics-based antibiofouling cello-oligosaccharide platforms Reviewed

    Kai Sugiura, Toshiki Sawada, Yuuki Hata, Hiroshi Tanaka, Takeshi Serizawa

    Journal of Materials Chemistry B   12 ( 3 )   650 - 657   2024.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Royal Society of Chemistry (RSC)  

    The conjugation of poly(ethylene glycol) (PEG) to therapeutic proteins or nanoparticles is a widely used pharmaceutical strategy to improve their therapeutic efficacy. However, conjugation can make PEG immunogenic and induce...

    DOI： 10.1039/d3tb01723k

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  • Nanospiked paper: Microfibrous cellulose materials nanostructured via partial hydrolysis and self-assembly Reviewed

    Yuuki Hata, Sumiyo Hiruma, Yuta Sakurai, Kai Sugiura, Hiromi Miyazaki, Takeshi Serizawa, Shingo Nakamura

    Carbohydrate Polymers   300   120257 - 120257   2023.1

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.carbpol.2022.120257

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  • Biofilm Degradation by Seashell-Derived Calcium Hydroxide and Hydrogen Peroxide Reviewed International journal

    Yuuki Hata, Yuta Bouda, Sumiyo Hiruma, Hiromi Miyazaki, Shingo Nakamura

    Nanomaterials   12 ( 20 )   3681 - 3681   2022.10

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Microbial cells and self-produced extracellular polymeric substances assembled to form biofilms that are difficult to remove from surfaces, causing problems in various fields. Seashell-derived calcium hydroxide, a sustainable inorganic material, has shown high bactericidal activity even for biofilms due to its alkalinity. However, its biofilm removal efficacy is relatively low. Herein, we report a biofilm degradation strategy that includes two environmentally friendly reagents: seashell-derived calcium hydroxide and hydrogen peroxide. A biofilm model of Escherichia coli was prepared in vitro, treated with calcium hydroxide–hydrogen peroxide solutions, and semi-quantified by the crystal violet stain method. The treatment significantly improved biofilm removal efficacy compared with treatments by calcium hydroxide alone and hydrogen peroxide alone. The mechanism was elucidated from calcium hydroxide–hydrogen peroxide solutions, which suggested that perhydroxyl anion and hydroxyl radical generated from hydrogen peroxide, as well as the alkalinity of calcium hydroxide, enhanced biofilm degradation. This study showed that concurrent use of other reagents, such as hydrogen peroxide, is a promising strategy for improving the biofilm degradation activity of seashell-derived calcium hydroxide and will contribute to developing efficient biofilm removal methods.

    DOI： 10.3390/nano12203681

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  • Recent Progress on Heparin–Protamine Particles for Biomedical Application Reviewed International journal

    Yuuki Hata, Hiromi Miyazaki, Masayuki Ishihara, Shingo Nakamura

    Polymers   14 ( 5 )   932 - 932   2022.2

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Biomolecules are attractive building blocks with self-assembly ability, structural diversity, and excellent functionality for creating artificial materials. Heparin and protamine, a clinically relevant pair of biomolecules used in cardiac and vascular surgery, have been shown to coassemble into particulate polyelectrolyte complexes in vitro. The resulting heparin–protamine particles exhibit adhesive properties that enable advantageous interactions with proteins, cells, and various other substances and have been employed as functional materials for biomedical applications. In this review article, we summarize recent progress in research on the use of heparin–protamine particles as drug carriers, cell adhesives, and cell labels. Studies have demonstrated that heparin–protamine particles are potentially versatile in biomedical fields from drug delivery and regenerative medicine to plastic surgery.

    DOI： 10.3390/polym14050932

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  • Effectivity of Scallop Shell-Derived Calcium Oxide Water in Comparison with Hypochlorous Acid and Ethanol as General-Purpose Disinfectants for Environmental Surfaces Reviewed

    Masayuki ISHIHARA, Sumiyo HIRUMA, Yuuki HATA, Shingo NAKAMURA, Atsuhiro KANAYAMA, Koki KAKU

    Japanese Journal of Infection Prevention and Control   36 ( 6 )   292 - 298   2021.11

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

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  • Recent Progress in the Development of Disinfectants from Scallop Shell-Derived Calcium Oxide for Clinical and Daily Use Reviewed

    Yuuki Hata, Masayuki Ishihara, Sumiyo Hiruma, Tomohiro Takayama, Shingo Nakamura, Naoko Ando

    Biocontrol Science   26 ( 3 )   129 - 135   2021.9

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：The Society for Antibacterial and Antifungal Agents, Japan  

    The current pandemic of novel coronavirus disease (COVID-19) has highlighted the importance of disinfectants. As a raw material for next-generation disinfectants, scallop shell-derived calcium oxide (CaO) has been revealed to exhibit significant virucidal and microbicidal activities and is compatible with living tissues and the environment. This minireview summarizes recent progress in the development of disinfectants from scallop shell-CaO, focusing especially on studies of clinical and daily use applications. We describe the preparation, basic characteristics, and virucidal and microbicidal activities of scallop shell-CaO disinfectants. Furthermore, their applications in the disinfection of contaminated masks and the treatment of infected wounds are briefly introduced.

    DOI： 10.4265/bio.26.129

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  • Robust Gels Composed of Self-Assembled Cello-oligosaccharide Networks Reviewed

    Yuuki Hata, Takeshi Serizawa

    Bulletin of the Chemical Society of Japan   94 ( 9 )   2279 - 2289   2021.7

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：The Chemical Society of Japan  

    DOI： 10.1246/bcsj.20210234

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  • Self-assembly of cellulose for creating green materials with tailor-made nanostructures Reviewed

    Yuuki Hata, Takeshi Serizawa

    Journal of Materials Chemistry B   9 ( 19 )   3944 - 3966   2021.4

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Royal Society of Chemistry (RSC)  

    <p>This review article summarizes recent research progress on the self-assembly of cellulose and the applications of assembled cellulose materials, especially for biomedical use.</p>

    DOI： 10.1039/d1tb00339a

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  • Efficacy of Bioshell Calcium Oxide Water as Disinfectants to Enable Face Mask Reuse Reviewed

    Sumiyo Hiruma, Yuuki Hata, Masayuki Ishihara, Tomohiro Takayama, Shingo Nakamura, Naoko Ando, Koichi Fukuda, Yoko Sato, Kaoru Murakami, Hidetaka Yokoe

    Biocontrol Science   26 ( 1 )   27 - 35   2021.3

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：The Society for Antibacterial and Antifungal Agents, Japan  

    Bioshell calcium oxide (BiSCaO) is derived from scallop shells and after heat treatment exhibits broad microbicidal activity. BiSCaO Water is a disinfectant prepared by collecting the aqueous layer after adding BiSCaO powder to water, is colorless and transparent, and has a pH of 12.8. We compared the utility of commercially available BiSCaO Water, ethanol, sodium hypochlorite, hypochlorous acid and hydrogen peroxide solutions as sterilization agents to enable the reuse of surgical and N95 face masks. The microbicidal efficacy of each disinfectant was evaluated using pieces of surgical and N95 face masks contaminated with normal bacterial flora. The results suggest that BiSCaO Water has excellent disinfection activity toward contaminated polypropylene masks and has minimal adverse effect on the structure of non-woven masks.

    DOI： 10.4265/bio.26.27

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  • Molecular crystallization directed by polymer size and overlap under dilute and crowded macromolecular conditions Reviewed

    Yuuki Hata, Xiang Li, Ung-il Chung, Takamasa Sakai

    Polymer Journal   53 ( 5 )   633 - 642   2021.2

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1038/s41428-021-00461-7

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    Other Link： http://www.nature.com/articles/s41428-021-00461-7

  • Structured liquids with interfacial robust assemblies of a nonionic crystalline surfactant Reviewed

    Yuuki Hata, Shohei Yoneda, Shoki Tanaka, Toshiki Sawada, Takeshi Serizawa

    Journal of Colloid and Interface Science   590   487 - 494   2021.1

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.jcis.2021.01.064

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  • Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes Reviewed

    Masayuki Ishihara, Yuuki Hata, Sumiyo Hiruma, Tomohiro Takayama, Shingo Nakamura, Yoko Sato, Naoko Ando, Koichi Fukuda, Kaoru Murakami, Hidetaka Yokoe

    Molecules   25 ( 19 )   4502 - 4502   2020.10

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the living body, given the strong alkalinity. This study aimed to investigate the safety of BiSCaO Water for use as an antiseptic/disinfectant despite concerns regarding its high alkalinity. The change over time in pH of BiSCaO Water was measured during air contact (stirring BiSCaO Water in ambient air). When sprayed on metal, plastic, wood piece, paper, and skin surfaces, the pH of BiSCaO Water decreased rapidly, providing a white powder coating upon drying. Scanning electron microscopy images, energy dispersive X-ray elemental mapping, and X-ray diffractograms showed that the dried powder residues of BiSCaO Water were composed primarily of calcium carbonate. These results suggested that BiSCaO Water is a potent reagent that may overcome the obstacles of being strongly alkaline, making this material appropriate for use in disinfection against pathogenic microbes.

    DOI： 10.3390/molecules25194502

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  • pH‐Triggered Self‐Assembly of Cellulose Oligomers with Gelatin into a Double‐Network Hydrogel Reviewed

    Yuuki Hata, Tomoya Kojima, Tohru Maeda, Toshiki Sawada, Takeshi Serizawa

    Macromolecular Bioscience   20 ( 9 )   2070020   2020.7

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1002/mabi.202000187

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  • Confined Reduced Graphene Oxides as a Platform for DNA Sensing in Solutions Crowded with Biomolecules Reviewed

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    ACS Applied Bio Materials   3 ( 5 )   3210 - 3216   2020.5

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

    DOI： 10.1021/acsabm.0c00206

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  • Assembly of Reduced Graphene Oxides into a Three-Dimensional Porous Structure via Confinement within Robust Cellulose Oligomer Networks Reviewed

    Yuuki Hata, Yoshitaka Saito, Toshiki Sawada, Hidetoshi Matsumoto, Takeshi Serizawa

    RSC Advances   9 ( 66 )   38848 - 38854   2019.11

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1039/C9RA08318A

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  • Biocatalytic Oligomerization-Induced Self-Assembly of Crystalline Cellulose Oligomers into Nanoribbon Networks Assisted by Organic Solvents Reviewed

    Yuuki Hata, Yuka Fukaya, Toshiki Sawada, Masahito Nishiura, Takeshi Serizawa

    Beilstein Journal of Nanotechnology   10   1778 - 1788   2019.8

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Beilstein Institut  

    DOI： 10.3762/bjnano.10.173

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  • Temperature-Directed Assembly of Crystalline Cellulose Oligomers into Kinetically Trapped Structures during Biocatalytic Synthesis Reviewed

    Yuuki Hata, Toshiki Sawada, Hironori Marubayashi, Shuichi Nojima, Takeshi Serizawa

    Langmuir   35 ( 21 )   7026 - 7034   2019.5

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acs.langmuir.9b00850

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  • Macromolecular Crowding for Materials-Directed Controlled Self-Assembly Reviewed

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Journal of Materials Chemistry B   6 ( 40 )   6344 - 6359   2018.9

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    <p>This review summarizes recent progress in research on macromolecular crowding for controlled self-assembly in the field of bio-related materials chemistry.</p>

    DOI： 10.1039/c8tb02201a

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  • Supramolecular Metal–Phenolic Gels for the Crystallization of Active Pharmaceutical Ingredients Reviewed

    Md. Arifur Rahim#, Yuuki Hata#, Mattias Björnmalm, Yi Ju, Frank Caruso

    Small   14 ( 26 )   1801202 - 1801202   2018.5

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1002/smll.201801202

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  • Enzyme-Catalyzed Bottom-Up Synthesis of Mechanically and Physicochemically Stable Cellulose Hydrogels for Spatial Immobilization of Functional Colloidal Particles Reviewed

    Yuuki Hata, Toshiki Sawada, Takamasa Sakai, Takeshi Serizawa

    Biomacromolecules   19 ( 4 )   1269 - 1275   2018.3

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acs.biomac.8b00092

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  • Effect of Solution Viscosity on the Production of Nanoribbon Network Hydrogels Composed of Enzymatically Synthesized Cellulose Oligomers under Macromolecular Crowding Conditions Reviewed

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Polymer Journal   49 ( 7 )   575 - 581   2017.4

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/pj.2017.22

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  • Enzymatic Synthesis of Cellulose Oligomer Hydrogels Composed of Crystalline Nanoribbon Networks under Macromolecular Crowding Conditions Reviewed

    Yuuki Hata, Tomoya Kojima, Taro Koizumi, Hiromichi Okura, Takamasa Sakai, Toshiki Sawada, Takeshi Serizawa

    ACS Macro Letters   6 ( 2 )   165 - 170   2017.2

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/acsmacrolett.6b00848

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Books

  • 界面制御による革新的生体適合性材料開発

    高井 まどか, 四方 志, 金 鋼, 松林 伸幸, 小林 慎吾, 田中 賢, 原田 慈久, 松村 和明, 遊佐 真一, 松川 祐子, 鈴木 一正, 大槻 主税, 菊池 明彦, 小松 周平, 冨田 峻介, 菅井 祥加, 白石 貢一, 菅谷 博之, 中田 克, 馬場 剛史, 藤田 雅規, 上野 良之, 森田 成昭, 小林 元康, 菱田 真史, 内橋 貴之, 宮田 一輝, 坂井 詠子, 佐藤 主税, 髙橋 泰伽, 岡村 陽介, 根本 知己, 秦 裕樹, 芹澤 武, 山本 玲子, 橋本 朋子, 薮塚 武史, 上田 恭介, 成島 尚之, 長瀬 健一, 村上 義彦, 鳥海 拓都, 森本 展行, 大谷 亨, 松崎 典弥, 鈴木 美加, 中村 奈緒子, 木村 剛, 林 智広, 辻 爽太郎, 星野 友, 村上 大樹, 松垣 あいら, 中野 貴由, 三浦 大和, 河﨑 陸, 宮田 隆志, 藤澤 七海, 荏原 充宏, 西口 昭広, 安江 華, 田口 哲志, 山本 雅哉, 宇都 甲一郎, 川田 楠旺, 中西 淳, 三浦 佳子, 長尾 匡憲, 仲本 正彦, 大矢根 綾子, 中村 真紀, 宮治 裕史, 山根 史帆里, 京本 政之, 茂呂 徹, 石原 一彦, 河村 暁文, 能﨑 優太, 金野 智浩, 山本 翔太, 合田 達郎, 堀井 辰衛, 藤枝 俊宣, 鳴瀧 彩絵, 黄 依璇（ Role： Contributor第9節 合成ナノセルロースの生体適合性とバイオ関連機能の評価）

    株式会社エヌ・ティー・エス  2025.12  （ ISBN:9784860437824 ）

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  • Constructing Functional Surfaces and Interfaces Using Low-Molecular-Weight Cellulose Invited

    Yuuki Hata, Takeshi Serizawa

    Journal of The Surface Finishing Society of Japan   76 ( 5 )   215 - 221   2025.5

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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  • セロオリゴ糖集合体のボトムアップ構築 Invited

    芹澤 武, 秦 裕樹

    高分子   73 ( 11 )   567 - 570   2024.11

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

    DOI： 10.1295/kobunshi.73.11_567

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  • リン酸基を利用したオリゴ糖自動合成 〜糖鎖合成におけるバイオインスパイアード戦略 Invited

    秦 裕樹

    化学   79 ( 8 )   63 - 64   2024.8

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

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  • Functionalization of cellulose materials via self-assembly of cello-oligosaccharides Invited

    Yuuki Hata, Takeshi Serizawa

    Glycoforum   26 ( 5 )   A20   2023.10

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

    DOI： 10.32285/glycoforum.26A20J

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  • 抗ウイルス性機能材料を開発するための金属類の利用 Invited

    中村 伸吾, 秦 裕樹, 宮﨑 裕美

    CBRNE SECURITY   5   37 - 41   2022.4

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (other)  

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  • Novel and simple methods for generating genetically modified mice using genome editing techniques

    Shingo Nakamura, Yuuki Hata

    Journal of the National Defense Medical College   46 ( 4 )   147 - 154   2021.12

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

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  • ホタテ貝殻焼成酸化カルシウムの殺菌・消毒剤としての有用性と安全性

    Journal of Antibacterial and Antifungal Agents   49 ( 8 )   405 - 411   2021.8

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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  • Nanocellulose Invited

    The Japanese Journal of Artificial Organs   48 ( 3 )   182 - 185   2019.12

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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  • Nanocelluloses: Their Properties and Applications toward Biomaterials Invited

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Journal of Japanese Society for Biomaterials   37 ( 1 )   24 - 29   2019.1

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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  • Nanostructural Control of Crystalline Cellulose Oligomers through Polymerization-Induced Self-Assembly under Macromolecular Crowding Conditions Invited

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Accounts of Materials & Surface Research   3 ( 1 )   1 - 7   2018.1

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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Presentations

  • 多糖を素材としたナノ構造化材料の構築と微⽣物制御への応⽤ Invited

    秦 裕樹

    第9回科学⼤応⽤化学系次世代を担う若⼿シンポジウム  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Venue：東京   Country：Japan  

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  • Nanostructuring Surfaces of Microfibrous Medical Materials via Self-Assembly of Cello-oligosaccharides for Microorganism Control Invited

    Yuuki Hata

    The 35th Annual Meeting of MRS-J  2025.11 

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    Event date： 2025.11

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Country：Japan  

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  • ナノ構造化材料のボトムアップ構築と微生物制御 Invited

    秦 裕樹

    関東高分子若手研究会 2025サマーキャンプ  2025.7 

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    Event date： 2025.7

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Venue：東京   Country：Japan  

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  • セロオリゴ糖を分子素材としたナノ構造化材料の構築とバイオ機能 Invited

    秦 裕樹

    24-1エコマテリアル研究会  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Venue：東京   Country：Japan  

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  • ナノ構造化表面のボトムアップ構築と微生物制御 Invited

    秦 裕樹

    第74回医用高分子研究会  2024.3 

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    Event date： 2024.3

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Venue：東京   Country：Japan  

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  • Construction of functional nanostructured materials via molecular self-assembly of cellulose Invited

    Yuuki Hata

    71st SPSJ Annual Meeting  2022.5 

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    Event date： 2022.5

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Country：Japan  

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  • Confinement of reduced graphene oxides within cellulose oligomer networks for constructing functional materials Invited

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    OKINAWA COLLOIDS 2019  2019.11 

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    Language：English   Presentation type：Oral presentation (invited, special)  

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  • Confinement of graphene oxides within cellulose oligomer gels for constructing functional materials Invited

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    The 10th Integrated Molecular / Materials Science & Engineering  2019.7 

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    Language：English   Presentation type：Oral presentation (invited, special)  

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  • セロオリゴ糖集合体に結合するペプチドの探索とその特性評価

    田代 真優, 澤田 敏樹, 秦 裕樹, 芹澤 武

    日本化学会第106春季年会  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：千葉   Country：Japan  

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  • アルキル基をもつ低分子量セルロースの界面集合化による堅牢な膜の形成

    鎌田 洋貴, 秦 裕樹, 杉浦 開, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会学生発表会・交流会2026  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • シート状セロオリゴ糖ナノ結晶からなる高熱伝導性フィルムの構築

    丸山 寛斗, 秦 裕樹, 原 光生, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会学生発表会・交流会2026  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • ヘキシル化セロオリゴ糖の分子配列制御：オリゴ糖鎖長の効果

    ほき本 亮介, 秦 裕樹, 芹澤 武

    関東高分子若手研究会学生発表会・交流会2026  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • プロテアーゼ応答型セロオリゴ糖微粒子の合成ならびに抗菌ペプチドの担持と放出

    坂田 トマ 健, 秦 裕樹, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会学生発表会・交流会2026  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • セロオリゴ糖集合体に結合するペプチドの探索とその結合特性評価

    田代 真優, 澤田 敏樹, 秦 裕樹, 芹澤 武

    関東高分子若手研究会学生発表会・交流会2026  2026.3 

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    Event date： 2026.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • Robust film formation via interfacial jamming of surface-alkylated synthetic nanocelluloses International conference

    Hirotaka Kamada, Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    The International Chemical Congress of Pacific Basin Societies 2025  2025.12 

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    Event date： 2025.12

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Honolulu   Country：United States  

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  • セロオリゴ糖による窒化ホウ素ナノチューブの水中分散

    柳 垂旻, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第35回日本MRS年次大会  2025.11 

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    Event date： 2025.11

    Language：Japanese   Presentation type：Poster presentation  

    Venue：福岡   Country：Japan  

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  • 動物細胞表面におけるセロオリゴ糖ナノシートの集積

    山本 和加子, 秦 裕樹, 芹澤 武

    第35回日本MRS年次大会  2025.11 

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    Event date： 2025.11

    Language：Japanese   Presentation type：Poster presentation  

    Venue：福岡   Country：Japan  

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  • ヘキシル化セロオリゴ糖からなるセルラーゼ応答型薬物キャリアの構築と特性解析

    Lee Jun Seok, 秦 裕樹, 芹澤 武

    第15回CSJ化学フェスタ2025  2025.10 

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    Event date： 2025.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 凍結融解を利⽤したセルロースナノファイバーの化学架橋によるゲル形成

    大場 将生, 秦 裕樹, 芹澤 武

    第15回CSJ化学フェスタ2025  2025.10 

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    Event date： 2025.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 両親媒性トリブロック高分子とセロオリゴ糖の共集合化によるゲル形成と特性評価

    久澤 果恋, 秦 裕樹, 芹澤 武

    第15回CSJ化学フェスタ2025  2025.10 

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    Event date： 2025.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • セロオリゴ糖を用いた窒化ホウ素ナノチューブの水中分散

    柳 垂旻, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第76回コロイドおよび界面化学討論会  2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：千葉   Country：Japan  

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  • 末端ヘキシル化セロオリゴ糖の分子配列制御：集合化温度とオリゴ糖鎖長の効果

    ホキ本 亮介, 秦 裕樹, 芹澤 武

    第74回高分子討論会  2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪   Country：Japan  

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  • Nanostructuring of microfibrous medical materials via self-assembly of cello-oligosaccharides for microorganism control

    2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • ナノフィラー含有ハイドロゲルの調製と細菌付着特性の解析

    熊田 真之, 秦 裕樹, 芹澤 武

    第74回高分子討論会  2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪   Country：Japan  

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  • プロテアーゼ応答型セロオリゴ糖微粒子の合成と抗菌ペプチドの担持

    坂田 トマ 健, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第74回高分子討論会  2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪   Country：Japan  

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  • セロオリゴ糖ナノシートを固相担体として用いる抗PEG抗体アッセイ

    杉浦 開, 秦 裕樹, 石橋 広一朗, 白石 貢一, 澤田 敏樹, 田中 浩士, 渡辺 豪, 芹澤 武

    第74回高分子討論会  2025.9 

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    Event date： 2025.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪   Country：Japan  

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  • プロパルギル化セロオリゴ糖ナノシートを固相担体として用いる抗PEG抗体アッセイ

    杉浦 開, 秦 裕樹, 石橋 広一朗, 澤田 敏樹, 田中 浩士, 渡辺 豪, 芹澤 武

    第35回バイオ・高分子シンポジウム  2025.7 

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    Event date： 2025.7 - 2025.8

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • ヘキシル化セロオリゴ糖からなるセルラーゼ応答型薬物キャリアの構築および特性解析

    Lee Jun Seok, 秦 裕樹, 芹澤 武

    第54回医用高分子シンポジウム  2025.7 

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    Event date： 2025.7

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • Nanospiked Cellulose Gauze Attracting Bacteria in Aqueous Protein Solutions for Reducing Bacterial Load in Burn Wounds International conference

    Yuuki Hata, Hiromi Miyazaki, Sayaka Okamoto, Shingo Nakamura, Takeshi Serizawa

    The 19th Pacific Polymer Conference  2025.7 

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    Event date： 2025.7

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Fukuoka   Country：Japan  

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  • Assays of Anti-PEG Antibodies Using Designable Cello-oligosaccharide Assemblies International conference

    Kai Sugiura, Yuuki Hata, Koichiro Ishibashi, Toshiki Sawada, Hiroshi Tanaka, Go Watanabe, Takeshi Serizawa

    The 19th Pacific Polymer Conference  2025.7 

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    Event date： 2025.7

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Fukuoka   Country：Japan  

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  • Top-down preparation of cello-oligosaccharides by phosphoric acid-catalyzed hydrolysis of cellulose and their self-assembly

    Yuuki HATA, Kosuke YOKOTA, Takeshi SERIZAWA

    74th SPSJ Annual Meeting  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • ナノロッド含有ハイドロゲルの調製と細菌付着特性の解析

    熊田 真之, 秦 裕樹, 芹澤 武

    第74回高分子学会年次大会  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Poster presentation  

    Venue：オンライン   Country：Japan  

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  • アルカリ条件下でのセロオリゴ糖の自己集合化による透明性の高いゲルの形成

    田代 真優, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第74回高分子学会年次大会  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Poster presentation  

    Venue：オンライン   Country：Japan  

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  • 表面アルキル化合成ナノセルロースの界面集合化に基づく堅牢膜の形成

    鎌田 洋貴, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第74回高分子学会年次大会  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

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  • ナノシート状セロオリゴ糖結晶からなる高熱伝導性フィルムの調製

    丸山 寛斗, 秦 裕樹, 原 光生, 澤田 敏樹, 芹澤 武

    第74回高分子学会年次大会  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

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  • ヘキシル化セロオリゴ糖の酵素合成温度による集合化制御

    ホキ本 亮介, 秦 裕樹, 芹澤 武

    第74回高分子学会年次大会  2025.5 

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    Event date： 2025.5

    Language：Japanese   Presentation type：Poster presentation  

    Venue：オンライン   Country：Japan  

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  • Anti-PEG Antibody Assays Using Designable Cello-oligosaccharide Assemblies as Solid-Phase Platforms

    Kai Sugiura, Koichiro Ishibashi, Yuuki Hata, Toshiki Sawada, Go Watanabe, Hiroshi Tanaka, Takeshi Serizawa

    2025.3 

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    Event date： 2025.3

    Language：English   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • ナノシート状セロオリゴ糖結晶からなる高熱伝導性フィルムの構築

    丸山 寛斗, 秦 裕樹, 原 光生, 澤田 敏樹, 芹澤 武

    日本化学会第105春季年会  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪   Country：Japan  

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  • ナノフィラー含有ハイドロゲルの調製と細菌付着特性の評価

    熊田 真之, 秦 裕樹, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2025  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 末端ヘキシル化セロオリゴ糖の集合構造制御：集合化温度と重合度の影響

    ホキ本 亮介, 秦 裕樹, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2025  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 設計可能なセロオリゴ糖集合体を固相担体として用いる抗PEG抗体アッセイ

    杉浦 開, 秦 裕樹, 石橋 広一朗, 澤田 敏樹, 田中 浩士, 渡辺 豪, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2025  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • セロオリゴ糖のアルカリ条件下での自己集合化による透明性の高いゲルの形成

    田代 真優, 秦 裕樹, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2025  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • ナノシート状セロオリゴ糖集合体からなる高熱伝導性フィルムの調製

    丸山 寛斗, 秦 裕樹, 原 光生, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2025  2025.3 

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 表面カルボキシル化セルロースオリゴマー集合体のタンパク質吸着特性

    松波 明里, 秦 裕樹, 芹澤 武

    第34回日本MRS年次大会  2024.12 

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    Event date： 2024.12

    Language：Japanese   Presentation type：Poster presentation  

    Venue：神奈川   Country：Japan  

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  • Construction of Plant–Animal Extracellular Matrix Chimera via Coassembly of Cello-oligosaccharides and Water-Soluble Polysaccharides International conference

    Takako Ida, Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    14th International Gel Symposium  2024.11 

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    Event date： 2024.11

    Language：English   Presentation type：Poster presentation  

    Venue：Okinawa   Country：Japan  

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  • Construction of Cellulose-Based Hybrid Polysaccharide Hydrogel Inspired by the Network Structure of Plant Cell Wall International conference

    Yuta Sakurai, Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    14th International Gel Symposium  2024.11 

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    Event date： 2024.11

    Language：English   Presentation type：Poster presentation  

    Venue：Okinawa   Country：Japan  

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  • ナノシート状セルロースオリゴマー集合体からなる高熱伝導性フィルムの構築

    丸山 寛斗, 秦 裕樹, 澤田 敏樹, 原 光生, 芹澤 武

    第14回 CSJ化学フェスタ2024  2024.10 

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    Event date： 2024.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • Fabrication of nanostructured materials via self-assembly of terminal functionalized cello-oligosaccharides for infection control

    Yuuki HATA, Sayaka OKAMOTO, LEE Jun Seok, Yudai MIZUUCHI, Takeshi SERIZAWA

    73rd Symposium on Macromolecules  2024.9 

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    Event date： 2024.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • セロオリゴ糖の自己集合化によるゲル形成と力学物性の向上

    田代 真優, 秦 裕樹, 澤田 敏樹, 丸林 弘典, 川村 出, 芹澤 武

    第73回高分子討論会  2024.9 

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    Event date： 2024.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：新潟   Country：Japan  

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  • 植物細胞壁の生合成に着想を得た酵素触媒重合による堅牢なセルロース-多糖ネットワーク構造の構築

    桜井 勇太, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第73回高分子討論会  2024.9 

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    Event date： 2024.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：新潟   Country：Japan  

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  • ナノシート状セロオリゴ糖集合体を用いる結合特異性の異なる抗PEG抗体の検出

    杉浦 開, 石橋 広一朗, 秦 裕樹, 澤田 敏樹, 渡辺 豪, 田中 浩士, 芹澤 武

    第75回コロイドおよび界面化学討論会  2024.9 

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    Event date： 2024.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：宮城   Country：Japan  

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  • セロオリゴ糖集合体を固相担体とした抗PEG抗体アッセイ

    杉浦 開, 秦 裕樹, 澤田 敏樹, 田中 浩士, 芹澤 武

    第34回バイオ・高分子シンポジウム  2024.8 

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    Event date： 2024.8

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • 表面アルキル化合成ナノセルロースの界面ジャミングと液体形状の捕捉

    鎌田 洋貴, 秦 裕樹, 杉浦 開, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会 2024 サマーキャンプ  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Poster presentation  

    Venue：山梨   Country：Japan  

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  • アルキル化セロオリゴ糖集合体の構築と微生物制御への応用

    秦 裕樹, 岡本 紗椰香, Lee Jun Seok, 芹澤 武

    第53回医用高分子シンポジウム  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • ヘキシル化セロオリゴ糖からなるセルラーゼ応答型薬物キャリアの構築と特性評価

    Lee Jun Seok, 秦 裕樹, 芹澤 武

    第53回医用高分子シンポジウム  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • Surface modification of cellulosic fibrous materials via self-assembly of cello-oligosaccharides for microorganism control

    Yuuki Hata, Yudai Mizuuchi, Sayaka Okamoto, Hiromi Miyazaki, Shingo Nakamura, Toshiki Sawada, Takeshi Serizawa

    73rd SPSJ Annual Meeting  2024.6 

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    Event date： 2024.6

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • Surface modification of cellulose fibers via self-assembly of alkylated cellulose oligomers and bacterial adhesion properties

    Sayaka Okamoto, Yuuki Hata, Takeshi Serizawa

    73rd SPSJ Annual Meeting  2024.6 

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    Event date： 2024.6

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • Analysis of cello-oligosaccharide production via phosphoric acid-catalyzed hydrolysis of cellulose

    Kosuke Yokota, Yuuki Hata, Takeshi Serizawa

    73rd SPSJ Annual Meeting  2024.6 

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    Event date： 2024.6

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

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  • アルキル化セロオリゴ糖集合体による疎水性薬物の担持と放出

    Lee Jun Seok, 秦 裕樹, 芹澤 武

    第73回高分子学会年次大会  2024.6 

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    Language：Japanese   Presentation type：Poster presentation  

    Venue：宮城   Country：Japan  

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  • 分子設計可能なセロオリゴ糖集合体による抗PEG抗体の識別

    杉浦 開, 秦 裕樹, 澤田 敏樹, 田中 浩士, 芹澤 武

    第73回高分子学会年次大会  2024.6 

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    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：宮城   Country：Japan  

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  • セルロースオリゴマーと水溶性多糖の共集合化による植物–動物キメラ型細胞外マトリックス様構造体の形成

    井田 貴子, 秦 裕樹, 澤田 敏樹, 芹澤 武

    日本化学会第104春季年会  2024.3 

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    Event date： 2024.3

    Language：Japanese  

    Venue：千葉   Country：Japan  

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  • ナノシート状セルロース集合体からなる高熱伝導性フィルムの構築

    丸山 寛斗, 秦 裕樹, 澤田 敏樹, 原 光生, 芹澤 武

    日本化学会第104春季年会  2024.3 

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    Event date： 2024.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：千葉   Country：Japan  

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  • セロオリゴ糖の中和誘起自己集合化の変調とゲル力学物性の向上

    田代 真優, 秦 裕樹, 澤田 敏樹, 川村 出, 芹澤 武

    日本化学会第104春季年会  2024.3 

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    Event date： 2024.3

    Language：Japanese  

    Venue：千葉   Country：Japan  

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  • 表面アルキル化合成ナノセルロースの界面集合に基づく液体形状の捕捉

    鎌田 洋貴, 秦 裕樹, 澤田 敏樹, 芹澤 武

    関東高分子若手研究会 学生発表会・交流会2024  2024.3 

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    Event date： 2024.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • セロオリゴ糖の自己集合化によるナノスパイク表面の構築と細菌付着挙動

    岡本 紗椰香, 秦 裕樹, 宮﨑 裕美, 中村 伸吾, 芹澤 武

    GlycoTOKYO2023  2023.12 

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    Event date： 2023.12

    Language：Japanese   Presentation type：Poster presentation  

    Venue：神奈川   Country：Japan  

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  • セルロースオリゴマーの中和誘起自己集合化を利用した機能性不織布の簡易構築

    水内 裕大, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第13回CSJ化学フェスタ2023  2023.10 

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    Event date： 2023.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • セルロースオリゴマー集合体へのリガンド導入とそれを利用した抗体検出

    末廣 芙弥, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第13回CSJ化学フェスタ2023  2023.10 

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    Event date： 2023.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • 自己集合化により形成するセルロースオリゴマーゲルの集合構造ならびに力学物性の制御

    田代 真優, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第13回CSJ化学フェスタ2023  2023.10 

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    Event date： 2023.10

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京   Country：Japan  

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  • Fabrication of cellulose gauze with nanospiked surfaces that adsorb bacteria

    Yuuki HATA, Hiromi MIYAZAKI, Shingo NAKAMURA, Takeshi SERIZAWA

    72nd Symposium on Macromolecules  2023.9 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • ナノシート状セルロース集合体からなるフィルムの構築と熱伝導性評価

    丸山 寛斗, 秦 裕樹, 澤田 敏樹, 原 光生, 芹澤 武

    第72回高分子討論会  2023.9 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：香川   Country：Japan  

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  • 植物細胞壁に着想を得たセルロースオリゴマー-多糖ネットワーク構造の構築

    桜井 勇太, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第72回高分子討論会  2023.9 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：香川   Country：Japan  

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  • セルロースオリゴマーと水溶性多糖の共集合化による植物–動物キメラ型細胞外マトリックス様構造体の構築

    井田 貴子, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第72回高分子討論会  2023.9 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：香川   Country：Japan  

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  • アルキル基を表面にもつシート状合成ナノセルロースの界面集合

    鎌田 洋貴, 秦 裕樹, 澤田 敏樹, 芹澤 武

    第74回コロイドおよび界面化学討論会  2023.9 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：長野   Country：Japan  

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  • セロオリゴ糖の自己集合化によるナノスパイク表面の構築と細菌付着特性

    秦 裕樹, 宮﨑 裕美, 中村 伸吾, 芹澤 武

    第33回バイオ・高分子シンポジウム  2023.7 

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    Event date： 2023.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • Fabrication and biomedical application of cellulose materials composed of microfibers with nanospike-structured surfaces

    Yuuki Hata, Hiromi Miyazaki, Takeshi Serizawa, Shingo Nakamura

    72nd SPSJ Annual Meeting  2023.5 

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    Event date： 2023.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • Research on nanostructure modification for developing biomass-derived antibacterial materials

    Yuuki Hata

    DSEI Japan  2023.3 

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    Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

    Country：Japan  

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  • Nanospike structure formation on microfiber surfaces of cellulose materials

    Yuuki Hata, Sumiyo Hiruma, Hiromi Miyazaki, Shingo Nakamura

    71st Symposium on Macromolecules  2022.9 

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    Event date： 2022.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • セルロースの加水分解と自己組織化による紙繊維表面でのナノスパイク構造形成

    秦 裕樹, 比留間 寿美代, 宮﨑 裕美, 中村 伸吾

    第32回バイオ・高分子シンポジウム  2022.7 

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    Event date： 2022.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

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  • Nanostructure Formation on Fiber Surfaces of Filter Paper via Hydrolysis and Self-Assembly of Cellulose

    Yuuki Hata, Sumiyo Hiruma, Hiromi Miyazaki, Shingo Nakamura

    The 102nd CSJ Annual Meeting  2022.3 

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    Event date： 2022.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • 貝殻由来酸化カルシウム水溶液によるマスクの除菌と再利用可能性

    秦 裕樹, 石原 雅之, 福田 孝一, 高山 智宏, 比留間 寿美代, 安藤 尚子, 村上 馨, 横江 秀隆, 中村 伸吾

    日本防菌防黴学会 第48回年次大会  2021.9 

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    Event date： 2021.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：オンライン   Country：Japan  

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  • Self-assembly of crystalline molecules directed by excluded volume and overlap of polymers

    Yuuki Hata, Xiang Li, Ung-il Chung, Shingo Nakamura, Takamasa Sakai

    70th Symposium on Macromolecules  2021.9 

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    Event date： 2021.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • 希薄およびクラウディング状態の高分子の排除体積と重なり合いによる分子結晶化の誘導

    秦 裕樹, Xiang Li, 鄭 雄一, 中村 伸吾, 酒井 崇匡

    第31回バイオ・高分子シンポジウム  2021.6 

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    Event date： 2021.6

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

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  • ⁃ Effect of excluded volume and overlap of polymers under dilute and crowding conditions on molecular crystallization

    2021.5 

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    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • Effect of excluded volume and overlap of dissolved polymers under dilute and crowding conditions on molecular crystallization

    Yuuki Hata, Xiang Li, Ung-il Chung, Takamasa Sakai

    The 101st CSJ Annual Meeting  2021.3 

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    Event date： 2021.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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  • One-step Preparation of Cellulose Hydrogels via Enzymatic Reactions in Molecularly Crowded Environments

    2016.5 

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  • Confinement of nanocarbons within robust networks composed of crystalline cellulose oligomers for applications

    2020.3 

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  • セルロースオリゴマーゲル中でのナノ材料の拘束とそれに基づく機能性材料の創製

    秦裕樹, 澤田敏樹, 芹澤武

    第29回バイオ・高分子シンポジウム  2019.7 

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  • Formation and applications of hybrid gels composed of reduced graphene oxides and cellulose oligomers via oligomerization-induced self-assembly

    2019.9 

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  • One-step Enzymatic Synthesis and Characterization of Cellulose-based Composite Hydrogels

    2015.5 

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  • 重症熱傷における易感染対策としてのミトコンドリア動態と品質管理機構の制御

    宮﨑 裕美, 木下 学, 秦 裕樹, 齋藤 大蔵, 中村 伸吾

    日本外科代謝栄養学会第59回学術集会  2022.7 

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    Venue：茨城   Country：Japan  

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  • セルロースナノ結晶存在下で酵素合成したセルロースハイドロゲルの特性評価

    秦 裕樹, 澤田敏樹, 芹澤 武

    第25回バイオ・高分子シンポジウム  2015.7 

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  • ファージディスプレイ法により獲得したナフタレン結合性ペプチドの機能評価

    秦 裕樹, 澤田敏樹, 芹澤 武

    第65回コロイド界面討論会  2014.9 

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  • Characterization of Sponge-like Cellulose Prepared by Enzymatic Synthesis in the Presence of Cellulose Nanocrystals

    2015.3 

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  • 縮合触媒としてのセルロースナノ結晶

    秦 裕樹, 澤田敏樹, 芹澤 武

    日本化学会第94春季年会  2014.3 

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  • ファージディスプレイ法によるナフタレン結合性ペプチドの同定と特性評価

    秦 裕樹, 澤田敏樹, 芹澤 武

    第46回若手ペプチド夏の勉強会  2014.8 

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  • Construction of functional materials through confinement of graphene oxides within cellulose oligomer gels

    2019.3 

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  • Control of self-assembly of cellulose oligomers by macromolecular crowding for the formation of nanoribbon gels

    2019.5 

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  • "Self-assembly of crystalline cellulose oligomers into hydrogels for spatial immobilization of colloidal particles "

    2018.3 

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  • Self-assembly of crystalline cellulose oligomers into hydrogels for spatial immobilization of functional colloidal particles

    2018.5 

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  • Enzymatic synthesis and functions of cellulose hydrogels composed of crystalline nanoribbon networks

    2017.5 

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  • セルロース系複合ハイドロゲルの創製：酵素触媒重合と分子クラウディングの接点

    秦裕樹, 澤田敏樹, 酒井崇匡, 芹澤武

    第27回バイオ・高分子シンポジウム  2017.7 

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  • Three-dimensional structuring of nanomaterials in crystalline cellulose oligomer gels and functional evaluation

    2018.11 

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  • 高分子クラウディングによるセルロースオリゴマーの自己集合化制御と機能性材料への展開

    秦裕樹

    関東高分子若手研究会2018年度 学生発表会・交流会  2019.3 

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    Language：Japanese   Presentation type：Oral presentation (general)  

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  • 結晶性セルロースオリゴマーからなる自己組織化ハイドロゲル中へのナノ材料の空間固定

    秦裕樹, 澤田敏樹, 酒井崇匡, 芹澤武

    第28回バイオ・高分子シンポジウム  2018.7 

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  • Three-dimensional structuring of nanomaterials in cellulose oligomer gels and functional evaluation

    2018.9 

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  • セルロースの酵素合成系を利用したダブルネットワークハイドロゲルの調製と特性評価

    小島知也, 秦 裕樹, 澤田敏樹, 芹澤 武

    日本化学会第97春季年会  2017.3 

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  • Enzymatic Synthesis and Characterization of All-Cellulose Nanocomposite Hydrogels

    Yuuki Hata, Toshiki Sawada, Takamasa Sakai, Takeshi Serizawa

    The 9th Integrated Molecular / Materials Science & Engineering  2016.10 

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    Language：English   Presentation type：Oral presentation (general)  

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  • Enzymatic Synthesis and Characterization of Cellulosic Hydrogels with Crystalline Nanoribbon Networks

    Yuuki Hata, Toshiki Sawada, Takamasa Sakai, Takeshi Serizawa

    The 11th SPSJ International Polymer Conference  2016.12 

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  • Enzymatic Synthesis and Characterization of All-Cellulose Composite Hydrogels

    2015.12 

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  • Enzymatic Synthesis and Characterization of Cellulose-based Composite Hydrogels

    Yuuki Hata, Toshiki Sawada, Takeshi Serizawa

    Pacifichem2015  2015.12 

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  • セルロースからなるハイドロゲルの酵素合成と特性評価

    秦 裕樹, 澤田敏樹, 酒井崇匡, 芹澤 武

    第5回CSJ化学フェスタ  2015.10 

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  • 酵素合成されたセルロースナノリボンからなるハイドロゲルの特性と機能

    秦 裕樹, 澤田敏樹, 酒井崇匡, 芹澤 武

    第45回医用高分子シンポジウム  2016.7 

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  • Enzymatic Synthesis and Characterization of Cellulose-based Nanocomposite Hydrogels

    2016.9 

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  • 分子クラウディング環境下で酵素合成したセルロースナノリボンからなるハイドロゲル

    秦 裕樹

    関東高分子若手研究会2015年度論文発表会  2016.3 

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Industrial property rights

  • セルロース三次元構造体及びその製造方法

    芹澤 武, 澤田 敏樹, 大倉 裕道, 秦 裕樹, 小泉 太郎, 三橋 秀一, 西澤 剛

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    Application no：特願2017-503744  Date applied：2016.3

    Announcement no：特開WO2016-140369  Date announced：2018.1

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Awards

  • 研究奨励賞（助教対象）

    2025.9   東京科学大学 物質理工学院  

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  • 研究奨励賞（助教対象）

    2024.9   School of Materials and Chemical Technology, Tokyo Institute of Technology  

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  • 高分子研究奨励賞

    2024.5   The Society of Polymer Science, Japan   Bottom-Up Construction of Nanostructured Cellulose for Developing Functional Materials

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    Award type：International academic award (Japan or overseas) 

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  • 研究奨励賞（助教対象）

    2023.9   School of Materials and Chemical Technology, Tokyo Institute of Technology  

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  • 令和元年度手島精一記念研究賞 博士論文賞

    2020.2   東京工業大学  

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  • 第29回バイオ・高分子シンポジウム 若手研究者奨励講演賞

    2019.7   バイオ・高分子研究会  

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  • 2018年度学生発表会・交流会 優秀口頭発表賞（博士）

    2019.3   関東高分子若手研究会  

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  • 第28回バイオ・高分子シンポジウム 学生優秀ポスター賞

    2018.7   バイオ・高分子研究会  

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  • 日本化学会第98春季年会 学生講演賞

    2018.3   日本化学会  

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  • 第45回医用高分子シンポジウム 優秀賞

    2016.7   医用高分子研究会  

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  • 2015年度論文発表会 優秀口頭発表賞（修士）

    2016.3   関東高分子若手研究会  

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  • 第25回日本MRS年次大会 奨励賞

    2015.12   日本MRS  

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  • 第64回高分子学会年次大会 優秀ポスター賞

    2015.5   高分子学会  

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Research Projects

  • Controlled Degradation of Cellulose to Produce Low-Molecular-Weight Cellulose for Artificial Nanocellulose Construction

    Grant number：26K08454  2026.4 - 2029.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Yuuki HATA

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    Authorship：Principal investigator  Grant type：Competitive

    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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  • 水浄化のための機能化人工ナノセルロース材料の創製

    2026.1 - 2027.12

    Toshiaki Ogasawara Memorial Foundation  Science and Technology Grants  General Research Grant

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    Authorship：Principal investigator  Grant type：Competitive

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  • Creation of nanospiked polymer materials for infection control

    Grant number：JPJ004596  2025.9 - 2028.3

    Acquisition, Technology & Logistics Agency  Innovative Science and Technology Initiative for Security  Type D

    Yuuki Hata, Takeshi Serizawa

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    Authorship：Principal investigator  Grant type：Competitive

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  • 結晶性セロオリゴ糖繊維によるカーボンナノチューブの拘束と光学特性

    2024.9 - 2025.3

    Tokyo Institute of Technology  Organization for Fundamental Research  A Grant-in-Aid for Challenging Research

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    Authorship：Principal investigator 

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  • カチオン性物質によるアルカリ系消毒剤の殺菌活性・毒性の制御

    2024.9 - 2025.3

    Tokyo Institute of Technology  Organization for Fundamental Research  A Grant-in-Aid for Challenging Research

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    Authorship：Principal investigator 

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  • Development of marine-degradable polymers independent of microorganisms and their application to material-recyclable cellulose nanofiber composites

    Grant number：JPMEERF20241RA1  2024.4 - 2027.3

    Environmental Restoration and Conservation Agency 

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    Authorship：Coinvestigator(s) 

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  • 糖鎖間相互作用に基づく多糖系複合ゲルの自在構築と機能開拓

    Grant number：24K01548  2024.4 - 2027.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant in Aid for Scientific Research (B)

    Takeshi Serizawa, Yuuki Hata

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    Authorship：Coinvestigator(s) 

    Grant amount：\18590000 （ Direct Cost: \14300000 、 Indirect Cost：\4290000 ）

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  • Creation of Nanostructured Medical Materials for Controlling Bacteria

    Grant number：24K17732  2024.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

    Yuuki HATA

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    Authorship：Principal investigator  Grant type：Competitive

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  • Evaluation of toxicity of alkaline disinfectants by skin-on-a-chip

    2023.8 - 2024.3

    Tokyo Institute of Technology  Tokyo Tech-TMDU Matching Fund 

    Yuuki Hata, Hirokazu Kaji, Takeshi Serizawa, Yuji Nashimoto, Takeshi Hori

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  • 対感染症個人防護具のための自己殺菌・ウイルス不活化複合材料の開発研究

    2022.6 - 2023.3

    National Defense Medical College 

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    Authorship：Principal investigator 

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  • 紙のテーラーメイドなナノ構造化と材料機能化

    2022.3 - 2024.2

    公益財団法人 松籟科学技術振興財団  研究助成事業  研究助成

    秦 裕樹

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    Authorship：Principal investigator 

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  • Bottom-Up Nanostructuring of Cellulose for Creating Functional Biomedical Materials

    Grant number：21K14688  2021.4 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

    Yuuki Hata

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    Authorship：Principal investigator 

    Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）

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  • Construction of Functional Nanostructured Materials Using a Designable Molecular Crowding System

    Grant number：20J01280  2020.4 - 2021.3

    Japan Society for the Promotion of Science  KAKENHI  Grant-in-Aid for JSPS Fellows

    Yuuki Hata

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    Authorship：Principal investigator 

    Grant amount：\4030000 （ Direct Cost: \3100000 、 Indirect Cost：\930000 ）

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  • セルロースのその場自己組織化を利用したナノコンポジット材料の創製

    Grant number：18J15025  2018.4 - 2020.3

    日本学術振興会  科学研究費助成事業 特別研究員奨励費  特別研究員奨励費

    秦 裕樹

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    Authorship：Principal investigator 

    Grant amount：\1900000 （ Direct Cost: \1900000 ）

    これまでに、ナノ材料のコロイド分散液中では酵素合成されたセルロースがその場でナノリボンネットワーク状の多孔体へと自己組織化することを利用して、セルロースナノ結晶（CNC）や酸化グラフェン（GO）といったナノ材料をその多孔体内部に分散固定できることを見出している。本年度は、GOを担持したナノリボン多孔体を機能性材料へと展開すること、ならびに分散固定に適用できるナノ材料種の多様化を目指した。
    まず、機能性材料への展開を検討した。GO担持ナノリボン多孔体をヨウ化水素により化学還元した結果、還元されたGOが緻密な多孔構造からなるゲルを形成した。これはGOが還元されて凝集性が高まっても分散固定により凝集抑制され、結果として沈殿せずに多孔構造形成したためと推察される。得られた還元型GOゲルは良好な電気伝導性を示し、さらに電気化学測定から、スーパーキャパシタの電極材料として機能することが明らかとなった。次いで、GO担持ナノリボン多孔体をバイオセンシングのためのプラットフォームとして応用した。すなわち、蛍光標識されたセンサーデオキシリボ核酸（DNA）が相補的なターゲットDNAと二重鎖形成するとナノリボン多孔体中のGO表面への吸着量が減少することを利用し、上清の蛍光測定によりセンシングを達成できた。重要なことに、GOが部分還元されている場合、その表面へのDNAの吸着が強いために、高濃度タンパク質夾雑下でも脱着することなくセンシングできることを見出した。
    次いで、分散固定できるナノ材料種の多様化を検討した。まず、従来のセルロース合成条件では、クレイ粒子やポリスチレン粒子が疎水性効果により凝集して沈殿し、分散固定できなかった。合成条件の系統的な探索の結果、合成温度を従来の60 ℃から30 ℃に低下させ、疎水性効果を低減させた場合、それら粒子もナノリボン多孔体中に分散固定できることを見出した。

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Other

  • Front Cover

    2026.1

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    Polymer Journal 2026, Volume 58, Issue 1.

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  • Front Cover

    2024.1

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    J. Mater. Chem. B 2024, 12, 543–543. https://doi.org/10.1039/D4TB90011A

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  • Front Cover

    2024.1

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    ACS Applied Bio Materials 2024, Volume 7, Issue 1.

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  • Editor’s Choice Article

    2022.2

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    Polymers 2022, Volume 14, Issue 5.

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  • Inside Cover

    2021.9

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    Bulletin of the Chemical Society of Japan 2021, Volume 94, Issue 9.

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  • Front Cover

    2021.5

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    J. Mater. Chem. B 2021, 9, 3937–3938. https://doi.org/10.1039/D1TB90078A

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  • Back Cover

    2020.9

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    Macromolecular Bioscience 2020, Volume 20, Issue 9, 2070020. https://doi.org/10.1002/mabi.202070020

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  • Supplementary Cover

    2020.5

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    ACS Applied Bio Materials 2020, Volume 3, Issue 5. https://pubs.acs.org/cms/10.1021/aabmcb.2020.3.issue-5/asset/aabmcb.2020.3.issue-5.xlargecover-3.jpg

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  • Supplementary Cover

    2019.5

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    Langmuir 2019, Volume 35, Issue 21. https://pubs.acs.org/cms/10.1021/langd5.2019.35.issue-21/asset/langd5.2019.35.issue-21.xlargecover-3.jpg

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  • Back Cover

    2018.10

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    J. Mater. Chem. B 2018, 6, 6491–6492. https://doi.org/10.1039/C8TB90149J

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  • ADVANCED SCIENCE NEWS "Gel-Mediated Crystallization of Active Pharmaceutical Ingredients"

    2018.7

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    https://www.advancedsciencenews.com/gel-mediated-crystallization-of-active-pharmaceutical-ingredients/

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  • Highlight Article

    2017.4

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    Polymer Journal 2017, Volume 49, Issue 7.

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Teaching Experience

  • Chemical Engineering and Industrial Chemistry Laboratory IV

    2024.10 Institution：Institute of Science Tokyo

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  • Polymer Chemistry Laboratory I & II

    2023.10 - 2024.3 Institution：Tokyo Institute of Technology

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  • Chemical Engineering and Industrial Chemistry Laboratory I

    2023.4 Institution：Tokyo Institute of Technology, Institute of Science Tokyo

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  • Chemical Engineering and Industrial Chemistry Laboratory III

    2023.4 - 2023.9 Institution：Tokyo Institute of Technology

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  • 科学技術と医療

    2022.12 Institution：国立看護大学校

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  • 化学

    2021.4 - 2023.3 Institution：防衛医科大学校

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  • 化学（実験）

    2021.4 - 2023.3 Institution：防衛医科大学校

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