Updated on 2025/10/16

写真a

 
MIYAZAKI MITSUHIKO
 
Organization
Institute of Integrated Research Laboratory for Chemistry and Life Science Visiting Associate Professor
Title
Visiting Associate Professor
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Degree

  • Doctor of Science ( Tohoku University )

Research Interests

  • molecular spectroscopy

  • cluster

  • quantum chemical calculation

Research Areas

  • Nanotechnology/Materials / Fundamental physical chemistry

Education

  • Tohoku University   Graduate School, Division of Natural Science   Department of Chemistry

    1999.4 - 2004.3

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    Country: Japan

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  • Tohoku University   Faculty of Science   Department of Chemistry

    1995.4 - 1999.3

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    Country: Japan

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Research History

  • Ochanomizu University   Associate Professor

    2019.10

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    Country:Japan

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  • Tokyo Institute of Technology   Institute of Innovative Research   Visiting Associate Professor

    2019.4 - 2019.9

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    Country:Japan

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  • Tokyo Institute of Technology   Assistant Professor

    2016.4 - 2019.3

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    Country:Japan

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  • Tokyo Institute of Technology   Chemical Resources Laboratory   Assistant Professor

    2007.4 - 2016.3

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  • Tokyo Institute of Technology   Integrated Research Institute, Solutions Research Organization   ソリューション研究員

    2005.11 - 2007.3

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  • Institute for Molecular Science   Department of Electronic Structure   IMS fellow

    2005.4 - 2005.10

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  • Kyoto University   Graduate school of science, Department of chemistry   21世紀COE博士研究員

    2004.4 - 2005.3

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Professional Memberships

Papers

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MISC

  • Advanced mid-infrared tunable laser and its application to novel spectraoscopy

    FUJII MASAAKI, MIYAZAKI MITSUHIKO, SAIKAWA JIRO, ISHIZUKI HIDEKI, TAIRA TAKUNORI

    電気学会光・量子デバイス研究会資料   OQD-11 ( 18-23 )   7-8 - 8   2011.3

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  • ZGP/PPLN/色素レーザーによる中赤外波長可変レーザーを用いた超音速分子線レーザー分光

    宮崎充彦, 斎川次郎, 石月秀貴, 平等拓範, 藤井正明

    Optics & Photonics Japan講演予稿集   2010   238-239   2010.11

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    Language:Japanese  

    J-GLOBAL

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  • Development of A High-Energy, Broadly Tunable and Narrow Band-Width Mid-Infrared Light Source and Its Application to Infrared-Ultraviolet Double Resonance Spectroscopy

    MIYAZAKI MITSUHIKO, SAIKAWA JIRO, FUJII MASAAKI, ISHIZUKI HIDEKI, TAIRA TAKUNORI

    レーザー研究   37 ( 4 )   296-303 - 303   2009.4

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    Language:Japanese   Publisher:一般社団法人 レーザー学会  

    We developed a high-energy, broadly tunable and narrow band-width mid-infrared light source with a

    DOI: 10.2184/lsj.37.296

    CiNii Books

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  • Development of a tunable mid-IR light source based on difference frequency generation in ZnGeP2 and its application to IR spectroscopy of jet-cooled species

    MIYAZAKI MITSUHIKO, SAIKAWA JIRO, FUJII MASAAKI, ISHIZUKI HIDEKI, TAIRA TAKUNORI

    日本化学会講演予稿集   89th ( 1 )   235   2009.3

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  • Real time observation of excited state hydrogen transfer reaction in phenol-(NH3)(n) (n=4, 5) clusters by ps time resolved infrared spectroscopy

    Miyazaki, Mitsuhiko, Ishiuchi, Shun-ichi, Sakai, Makoto, Fujii, Masaaki

    Abstracts of Papers of the American Chemical Society   238   2009

  • 光で繋ぐ理研の基礎科学 大口径PPMgLN素子とZnGeP2結晶を用いた広帯域波長可変・高分解能中赤外光源

    石月秀貴, 平等拓範, 齊川次郎, 宮崎充彦, 藤井正明

    エクストリームフォトニクスシンポジウム−光で繋ぐ理研の基礎科学 平成21年   121-122   2009

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    Language:Japanese  

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  • Narrow-bandwidth Mid-IR generation based on a large aperture periodically poled Mg-doped LiNbO(3) optical parametric pump system

    Saikawa, J., Miyazaki, M., Fujii, M., Ishizuki, H., Taira, T., IEEE

    2008 Conference on Lasers and Electro-Optics & Quantum Electronics and Laser Science Conference, Vols 1-9   2008

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Presentations

  • MATI-IR分光法によるResorcinol-Arn (n = 1, 2)クラスターにおけるAr原子移動反応の観測

    肥後 夢乃, 宮﨑 充彦

    日本化学会第104春季年会  2024.3  日本化学会

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    Event date: 2024.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:日本大学理学部船橋キャンパス  

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  • 4-Aminobenzonitrile+–Ar1クラスターカチオンに於けるAr原子π → H移動障壁の実験的決定

    湯汲 紫音, 宮﨑 充彦

    第17回分子科学討論会  2023.9  分子科学会

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪大学豊中キャンパス  

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  • ベンゼン水和クラスターの赤外分光法によるエネルギー選択的に加熱した氷の構造観測

    中島 梨々香, 宮﨑 充彦

    第17回分子科学討論会  2023.9  分子科学会

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    Event date: 2023.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪大学豊中キャンパス  

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  • Ionization induced hydration rearrangement in the 4-aminobenzonitrile–(H2O)2 cluster – An insight into the effect of solvent-solvent hydrogen bonding interactions – Invited International conference

    Mitsuhiko Miyazaki, Risako Matsuno

    8th Asian Spectroscopy Conference 2023  2023.9  The organizing committee of 8th Asian Spectroscopy Conference 2023

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    Event date: 2023.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Atema Kogen, Niigata, Japan   Country:Japan  

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  • Direct observation of hydration structure relaxation - Ionization induced reorientation around 4-aminobenzonitrile–water by picosecond time resolved IR spectroscopy - Invited International conference

    MIYAZAKI Mitsuhiko, NAKAMURA Takashi, WEILER Martin, FUJII Masaaki

    Gordon Research Conferences: Molecular and Ionic Clusters 2014  2014.4  Gordon Research Conferences

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    Language:English  

    Venue:Il Ciocco, Italy  

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  • Real time observation of photoionization induced isomerization dynamics of acetanilide-water cluster by ps time resolved infrared spectroscopy Invited International conference

    MIYAZAKI Mitsuhiko

    The 3rd symposium on gas phase reaction dynamics and laser spectroscopy  2011.8  Korean Chemical Society

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    Language:English  

    Venue:Daejeon, Korea  

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  • Real Time Dynamics of Ionization Induced Water Reorientation in Acetanilide–Water Cluster Invited International conference

    MIYAZAKI Mitsuhiko, TANABE Kohei, WEILER Martin, FUJII Masaaki

    The 15th Asian Chemical Congress  2013.8  Asian Chemical Society

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    Language:English  

    Venue:Singapole, Singapole  

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  • A novel pathway of excited state hydrogen transfer reaction in phenol-(NH3)n —A picosecond time resolved study Invited International conference

    MIYAZAKI Mitsuhiko

    New Horizons of Cluster Chemistry  2010.10  Kobe University

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    Venue:Kobe, Japan  

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  • Photoionization-induced water reorientation in the 5-hydroxyindole water cluster –A challenge to real-time observation of slow dynamics– Invited International conference

    MIYAZAKI Mitsuhiko

    The 20th East Asian Workshop on Chemical Dynamics  2016.6  National Sun Yat Sen University

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    Venue:Kaohsiung, Taiwan  

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  • ピコ秒時間分解分光による分子クラスターを用いた化学反応素過程への構造論的アプローチ Invited

    宮﨑 充彦

    第10回分子科学会  2016.9  分子科学会

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    Language:Japanese  

    Venue:神戸(日本)  

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  • Mechanism of the Ionization Induced Isomerization of Phenol–Ar Cluster Studied by Mass Analyzed Threshold Ionization Detected Infrared Spectroscopy International conference

    MIYAZAKI Mitsuhiko, MÜLLER-DETHLEFS Klaus, DOPFER Otto, FUJII Masaaki

    The 2015 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2015)  2015.12 

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    Language:English  

    Venue:Honolulu, USA  

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  • Real-time observation of photoionization-induced water migration in 5-hydroxyindole-water cluster International conference

    NAITO Ayumi, MIYAZAKI Mitsuhiko, IMAJO Takashi, SEKIYA Hiroshi, FUJII Masaaki

    The 2015 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2015)  2015.12 

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    Venue:Honolulu, USA  

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  • ナノ秒及びピコ秒時間分解赤外分光法による分子クラスター内反応の研究 Invited

    宮﨑 充彦

    平成26年度 日本分光学会年次講演会  2014.5  日本分光学会

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    Venue:和光市(日本)  

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  • Real-time observation of intramolecular charge transfer dynamics in the (p-cyanophenyl)pentamethyldisilane–water cluster by picosecond time resolved IR spectroscopy Invited International conference

    MIYAZAKI Mitsuhiko

    45th World Chemistry Congress (IUPAC 2015)  2015.8  IUPAC

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    Venue:Busan, Korea  

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  • Water migration dynamics in hydrated clusters -- Real-time observation by time-resolved IR spectrosocpy -- Invited International conference

    MIYAZAKI Mitsuhiko

    International Symposium on Molecular Science - Physical Chemistry / Theoretical Chemistry, Chemoinformatics, Computational Chemistry  2019.3  Chemical Society of Japan

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    Venue:Kobe, Japan  

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  • フェノール‐アンモニアクラスターの励起状態プロトン共役電子移動反応に関する理論的研究

    岩田 健一郎, 堤 拓朗, 和田 諒, 斉田 健一郎, 宮﨑 充彦, 武次 徹也

    分子科学会オンライン討論会  2020.9  分子科学会

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    Language:Japanese  

    Venue:オンライン  

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  • Real-time observation of charge transfer dynamics in a (p-cyanophenyl)pentamethyldisilane–water cluster by picosecond time-resolved IR spectroscopy International conference

    MIYAZAKI Mitsuhiko, MATSUYAMA Saori, ISHIKAWA Haruki, FUJII Masaaki

    XVIII Time Resolved Vibrational Spectroscopy 2017  2017.6 

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    Venue:Cambridge, UK  

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  • Real-time observation of slow water rearrangement dynamics in the 5-hydroxyindole-water cluster cation by time-resolved IR spectroscopy Invited International conference

    MIYAZAKI Mitsuhiko, NAITO Ayumi, IKEDA Takamasa, SEKIYA Hiroshi, KLYNE Johanna, DOPFER Otto, FUJII Masaaki

    Gordon Research Conferences: Molecular and Ionic Clusters 2018  2018.2  Gordon Research Conferences

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    Language:English  

    Venue:Il Ciocco, Italy  

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  • Real-time observation of twisted intramolecular charge transfer (TICT) and hydration dynamics in (p-cyanophenyl)pentamethyldisilane (CPDS)-water clusters by picosecond time-resolved IR spectroscopy International conference

    Mitsuhiko Miyazaki, Haruki Ishikawa, Masaaki Fujii

    The 2021 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2021)  2021.12 

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  • 光イオン化で誘起される4‐アミノベンゾニトリル‐水1:2クラスターの水分子マイグレーションの赤外分光による観測

    松野 里早子, 宮﨑 充彦

    第15回分子科学会討論会  2021.9  分子科学会

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  • On the fly MD法によるフェノール‐アンモニア系の励起状態反応ダイナミクス

    岩田 健一郎, 堤 拓朗, 斉田 健一郎, 宮﨑 充彦, 武次 徹也

    第15回分子科学会討論会  2021.9  分子科学会

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  • フェノール-アンモニアクラスターの励起状態プロトン共役電子移動ダイナミクスの解明

    岩田 健一郎, 堤 拓朗, 斉田 謙一郎, 宮崎 充彦, 武次 徹也

    第23回理論科学討論会  2021.5 

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Awards

  • research fellowship for experienced scientists

    2017.3   Alexander von Humboldt Foundation  

    Mitsuhiko Miyazaki

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  • Research fellowship for experienced scientists

    2017.3   Alexander von Humboldt Foundation   Intersolvent Interactions from Structure and Dynamics of Solvated Clusters

    MIYAZAKI Mitsuhiko

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  • 分子科学会 奨励賞

    2015.9   分子科学会   ナノ秒およびピコ秒時間分解赤外分光法による分子クラスター内化学反応の研究

    宮﨑 充彦

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    Country:Japan

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  • 分子科学会奨励賞

    2015.9   分子科学会   ナノ秒およびピコ秒時間分解赤外分光法による分子クラスター内化学反応の研究

    宮﨑 充彦

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  • 奨励賞

    2013.11   日本分光学会   ナノ秒及びピコ秒時間分解赤外分光法による分子クラスター内反応の研究

    宮﨑 充彦

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Research Projects

  • ナノ秒‐ピコ秒時間分解赤外分光の開発による溶媒再配向における溶媒間相互作用の解明 International coauthorship

    2024.4 - 2027.3

    独立行政法人日本学術振興会  科学研究費助成事業  基盤研究(C)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

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  • 赤外分光による芳香族二量体およびクラスターの電荷共鳴状態の研究 International coauthorship

    2023.4 - 2024.3

    独立行政法人日本学術振興会  二国間交流事業 オープンパートナーシップ共同研究  未設定

    松本 剛昭

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\2000000

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  • 冷却イオントラップ分光による天然変性タンパク質複合体へのボトムアップアプローチ

    Grant number:20K20446  2020.4 - 2023.3

    日本学術振興会  科学研究費助成事業  挑戦的研究(開拓)

    藤井 正明, 石内 俊一, 平田 圭祐, 宮崎 充彦

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    Grant amount:\26000000 ( Direct Cost: \20000000 、 Indirect Cost:\6000000 )

    1)YEMPS-ドーパおよびノルアドレナリン複合体のの冷却イオントラップ赤外分光
    天然変性タンパク質であるα-シヌクレインのドーパミン結合部位にはドーパミン誘導体であるドーパやノルアドレナリンも結合することが分かっている。そこで,YEMPS配列の部分ペプチドAc-YEMPS-NHMe(以降YEMPS)とプロトン付加ドーパおよびプロトン付加ノルアドレナリンの複合体をエレクトロスプレーで気相中に取り出し,冷却イオントラップ中の極低温下で赤外スペクトルを測定した。ドーパミン複合体の場合と同様に,プロトン化アミノ基がYEMPSと優先的に結合するのを阻害するために,18C6クラウンエーテルでプロトン化アミノ基を包接保護した。その結果,これら2つの複合体でも,YEMPSとカテコールOH基が結合した構造を形成させることができた。YEMPSの2 次構造を明らかにするために,ペプチド結合のC=O伸縮振動(amide-I)を測定したところ,1650 cm-1にバンドが観測され,α-ヘリックス構造が形成されていることが確認された。従って,ドーパミンと同様に,ドーパやノルアドレナリンも複合体形成によりYEMPSにヘリックス構造を誘起することが分かった。
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    2)異性体分離したスペクトル測定法の検討
    クラウンエーテルを付加した複合体ではUVスペクトルの測定が困難なため,UVスペクトルを用いた異性体分離ができない。そこで,IRスペクトルのみを用いて異性体分離したスペクトルを測定する方法であるIR-IR dip分光法を用いる必要があるが,これを実現するためには,1本目のIR照射と2本目のIR照射の間で質量分析する必要があり,現有装置では困難である。そのため,冷却イオントラップの後の線形飛行時間方質量分析器を2段の質量分析器に改造する必要があり,最適な方法をイオン軌道シミュレーションを用いて確立した。

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  • The role of intermolecular interaction in solvent reorientation dynamics ---A molecular scopic study utilizing time-resolved IR spectroscopy---

    Grant number:19K05368  2019.11 - 2023.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

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  • 時間・エネルギー極限分光の開発と溶媒再配向ダイナミクスへの分子論的アプローチ

    2018

    日本学術振興機構  若手研究(A)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \2500000 )

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  • 新奇高強度中赤外光源の開発とDNA塩基の脱励起メカニズム

    2017

    日本学術振興機構  挑戦的萌芽研究

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \410000 )

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  • 時間・エネルギー極限分光の開発と溶媒再配向ダイナミクスへの分子論的アプローチ

    2017

    日本学術振興会  若手研究(A)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \5600000 )

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  • 時間・エネルギー極限分光の開発と溶媒再配向ダイナミクスへの分子論的アプローチ

    2016

    日本学術振興機構  若手研究(A)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \6900000 )

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  • 新奇高強度中赤外光源の開発とDNA塩基の脱励起メカニズム

    2016

    日本学術振興機構  挑戦的萌芽研究

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \180000 )

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  • Understanding the electron-proton decoupling effect in the hydrogen/proton transfer reaction by electron-nucleus conjugated measurements

    Grant number:15H02157  2015.4 - 2019.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

    Fujii Masaaki

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    Grant amount:\44850000 ( Direct Cost: \34500000 、 Indirect Cost:\10350000 )

    In this project, a femtosecond time-resolved near infrared-ultraviolet spectroscopy on gas phase solvated clusters was developed, and this method was applied to the phenol-(ammonia)5 cluster to investigate the mechanism of the excited-state hydrogen transfer reaction.
    The reaction dynamics was composed of an electron transfer with ca. 350 fs and a proton transfer with ca. 20 ps. This result means that the electron and the proton transfer processes proceeds in totally different time-scales, i.e. there is decoupling between the electron and the proton though this reaction is a hydrogen transfer reaction.
    The decoupling mechanism stems from a strong coupling of the pi-sigma* state with a charge-separated state. Solvation strongly affects the stability of the charge separated state and also changes the degree of the decoupling.

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  • 新奇高強度中赤外光源の開発とDNA塩基の脱励起メカニズム

    2015

    日本学術振興機構  挑戦的萌芽研究

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \2410000 )

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  • Structural diversity and hydration dynamics of hydrogen bonding system studied by gas-phase spectroscopy

    Grant number:25104008  2013.6 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

    Fujii Masaaki

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    Grant amount:\89180000 ( Direct Cost: \68600000 、 Indirect Cost:\20580000 )

    Electrospray cryogenic ion trap spectrometer was developed, and applied to complexes of partial sequence of receptor proteins and several ligands to reveal their interactions at molecular level. In addition, hydration effects on their structures were clarified by using hydrated clusters in which number of water molecules and their orientation can be rigorously determined. Furthermore, Structures of alkali metal ion complexes of biomolecules were investigated by using isomer-selected infrared spectroscopy, and conformational specificity depending on the alkali metal ions was revealed. Through these results, we successfully demonstrated that precise spectroscopic studies on the interaction centers cut out from biomolecules, i.e., "bottom-up approach" is useful.

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  • Conformation-selective picosecond pump-probe time resolved spectroscopy of DNA bases and peptides in the gas phase

    2013

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \1200000 )

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  • 高強度中赤外光源を用いた励起状態プロトン移動反応機構の構造論的研究

    2013

    日本学術振興機構  基盤研究(C)(1)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \400000 )

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  • エネルギーおよび時間分解分光による気相生体関連分子の構造と励起状態ダイナミクス

    2011

    日本学術振興機構  二国間交流事業(韓国との共同研究)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \1196000 )

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  • 高強度中赤外光源を用いた励起状態プロトン移動反応機構の構造論的研究

    2011

    日本学術振興機構  基盤研究(C)(1)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \3600000 )

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  • エネルギーおよび時間分解分光による気相生体関連分子の構造と励起状態ダイナミクス

    2010

    日本学術振興機構  二国間交流事業(韓国との共同研究)

    宮﨑 充彦

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    Authorship:Principal investigator  Grant type:Competitive

    Direct Cost: \1200000 )

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  • Development of a high power mid infrared laser and study on the mechanism of excited state proton/hydrogen transfer reaction

    Grant number:21750013  2009 - 2010

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    MIYAZAKI Mitsuhiko

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    Grant amount:\4810000 ( Direct Cost: \3700000 、 Indirect Cost:\1110000 )

    I developed new tunable coherent infrared source in the mid-infrared (MIR) region that is applicable to supersonic jet infrared spectroscopies. The light source can provides continuous tunability covering 1000-2200cm^<-1> with the output of >0.5mJ/pulse and the energy resolution of <0.4cm^<-1>, which are necessary conditions to perform double resonance spectroscopies on supersonically cooled species.
    Applications of the MIR laser to the infrared spectroscopy of the skeletal vibrations of several reactive systems, such as phenol-ammonia clusters, methylsalicylate shed new insight into their proton transfer reaction mechanisms that have been inferred only from uninformative broad spectroscopic features.

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  • spectroscopic studies on structures and reactions of gas phase molecular clusters

    2004

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    Grant type:Competitive

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