Updated on 2025/02/28

写真a

 
KAJIKAWA MASAKI
 
Organization
School of Life Science and Technology Lecturer
Title
Lecturer
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Degree

  • Doctor of Science ( Tokyo Institute of Technology )

Research Interests

  • 分子生物学

  • Molecular Biology

Research Areas

  • Life Science / Genetics

Education

  • Tokyo Institute of Technology   Graduate School, Division of Life Science and Engineering

    - 2003

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  • 東京工業大学大学院   生命理工学研究科   バイオサイエンス専攻

    - 2003

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    Country: Japan

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  • Tokyo Institute of Technology   School of Bioscience and Biotechnology

    - 1998

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    Country: Japan

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Research History

  • -:Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Research associate

    2003

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  • -:東京工業大学 大学院生命理工学研究科 助手

    2003

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MISC

  • LINEs mobilize SINEs in the eel through a shared 3 ' sequence

    M Kajikawa, N Okada

    CELL   111 ( 3 )   433 - 444   2002.11

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    Language:English   Publisher:CELL PRESS  

    We characterized members of the LINE (UnaL2) and SINE (UnaSINE1) families from the eel genome and found that these LINE/SINE partners share similar 3' tails. A retrotransposition assay in HeLa cells demonstrated that the 3' conserved tail of UnaL2 is necessary for its retrotransposition. This 3' tail is recognized in trans by the UnaL2 reverse transcriptase at a surprisingly high rate, and that of UnaSINE1 can also be recognized, thus providing experimental evidence that a SINE can be mobilized by the retrotransposition machinery of a partner LINE. We also demonstrated that short repeats at the 3' end of UnaL2 are required for retrotransposition suggesting that UnaL2 retrotransposes in a manner reminiscent of the reverse transcriptase activity of telomerases.

    DOI: 10.1016/S0092-8674(02)01041-3

    Web of Science

    PubMed

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  • LINEs mobilize SINEs in the eel through a shared 3’ sequence.

    Kajikawa, M. Okada, N

    Cell   111 ( 3 )   433 - 444   2002

  • Determination of the entire sequence of turtle CR1: the first open reading frame of the turtle CR1 element encodes a protein with a novel zinc finger motif.

    Kajikawa M. Ohshima, K. Okada, N

    Mol. Biol. Evol.   14   1206   1997

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  • Determination of the entire sequence of turtle CR1: the first open reading frame of the turtle CR1 element encodes a protein with a novel zinc finger motif.

    Kajikawa M. Ohshima, K. Okada, N

    Mol. Biol. Evol.   14   1206   1997

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Presentations

  • Novel sex pheromone desaturases in the genomes of corn borers generated through gene duplication and retroposon fusion.

    Proc Natl Acad Sci U S A.  2007 

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  • Novel retrotransposon analysis reveals multiple mobility pathways dictated by hosts.

    Genome Res.  2007 

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  • A new system for analyzing LINE retrotransposition in the chicken DT40 cell line widely used for reverse genetics.

    GENE,  2007 

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  • Functional splice sites in a zebrafish LINE and their influence on zebrafish gene expression.

    Gene.  2007 

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  • Novel sex pheromone desaturases in the genomes of corn borers generated through gene duplication and retroposon fusion.

    Proc Natl Acad Sci U S A.  2007 

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  • Novel retrotransposon analysis reveals multiple mobility pathways dictated by hosts.

    Genome Res.  2007 

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  • A new system for analyzing LINE retrotransposition in the chicken DT40 cell line widely used for reverse genetics.

    GENE,  2007 

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  • Functional splice sites in a zebrafish LINE and their influence on zebrafish gene expression.

    Gene.  2007 

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